2023
Combination HIV prevention during pregnancy and the post‐partum period in Malawi and Zambia: a mathematical modelling analysis
Powers K, Mutale W, Rosenberg N, Graybill L, Mollan K, Freeborn K, Saidi F, Maman S, Mulenga P, Jahn A, Nyirenda R, Stringer J, Vermund S, H. B. Combination HIV prevention during pregnancy and the post‐partum period in Malawi and Zambia: a mathematical modelling analysis. Journal Of The International AIDS Society 2023, 26: e26128. PMID: 37403422, PMCID: PMC10320044, DOI: 10.1002/jia2.26128.Peer-Reviewed Original ResearchConceptsFemale HIV transmissionMaternal HIV acquisitionMaternal HIV incidenceHIV prevention strategiesPost-partum periodAntiretroviral therapyHIV transmissionMale partnersHIV acquisitionHIV incidenceANC patientsPrevention strategiesCombination HIV prevention strategiesCombination HIV prevention interventionSuppressive antiretroviral therapyPre-exposure prophylaxisVertical HIV transmissionAntenatal care programsCombination HIV preventionHIV prevention interventionsANC initiationART initiationUnsuppressed HIVIncident infectionsUndiagnosed HIV
2022
Voluntary Medical Male Circumcision for HIV Prevention: a Global Overview
Zhang C, Vermund S. Voluntary Medical Male Circumcision for HIV Prevention: a Global Overview. Current HIV/AIDS Reports 2022, 19: 474-483. PMID: 36348186, DOI: 10.1007/s11904-022-00632-y.Peer-Reviewed Original ResearchConceptsVoluntary medical male circumcisionMedical male circumcisionHIV preventionMale circumcisionPrevention strategiesEvidence-based HIV prevention strategiesBehavioral prevention strategiesHigher sexual risk behaviorsHIV prevention strategiesSexual risk behaviorsPurpose of ReviewWithDecreased riskClinical trialsCircumcision coverageVMMC coverageProtective effectRecent FindingsThereHealth professionalsSystematic reviewIncidence areaRisk behaviorsSexual partnersHealth authoritiesHealth systemMale partners
2014
A-101 New Evidence that Circumcision Might Protect MSM from HIV
Vermund S, Qian H, Ruan Y, Shao Y, Liu Y, Milam D, Spiegel H, Li D, Yin L. A-101 New Evidence that Circumcision Might Protect MSM from HIV. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2014, 67: 37. DOI: 10.1097/01.qai.0000456053.93927.60.Peer-Reviewed Original ResearchInsertive anal sexAnal sexUncircumcised menCircumcision statusMale circumcisionMultivariate logistic regression analysisOdds of HIVUnknown HIV statusHIV prevention strategiesCross-sectional studyInsertive anal intercourseLogistic regression analysisAnal sex rolesAdjusted riskHIV clinicSyphilis infectionHIV statusClinical trialsCircumcision ratesGenital examinationAnal intercourseLower oddsGenital examHIVPrevention strategiesModeling the Impact on HIV Incidence of Combination Prevention Strategies among Men Who Have Sex with Men in Beijing, China
Lou J, Blevins M, Ruan Y, Vermund SH, Tang S, Webb GF, Shepherd BE, He X, Lu H, Shao Y, Qian HZ. Modeling the Impact on HIV Incidence of Combination Prevention Strategies among Men Who Have Sex with Men in Beijing, China. PLOS ONE 2014, 9: e90985. PMID: 24626165, PMCID: PMC3953201, DOI: 10.1371/journal.pone.0090985.Peer-Reviewed Original ResearchConceptsAntiretroviral therapyHIV epidemicCondom useHIV prevalenceART coverageCombination prevention strategiesHIV/AIDSHIV testingHIV incidenceCombination interventionsBeijing MSMPrevention strategiesPrevalence estimatesPrevalenceEpidemic expansionMenInterventionEpidemicIncidenceBasic reproduction numberPrevention scenariosCurrent coverageSexReproduction numberIntervention levels
2013
Translation of Biomedical Prevention Strategies for HIV
Vermund SH, Tique JA, Cassell HM, Pask ME, Ciampa PJ, Audet CM. Translation of Biomedical Prevention Strategies for HIV. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2013, 63: s12-s25. PMID: 23673881, PMCID: PMC3725750, DOI: 10.1097/qai.0b013e31829202a2.Peer-Reviewed Original ResearchConceptsPrevention of motherPrevention strategiesClean injection equipmentChild HIV transmissionBiomedical approachBiomedical prevention strategiesRisk of acquisitionHIV prevention strategiesBehavioral risk reductionHigh-prevalence regionsRisk of transmissionCircumcision of menBlood product safetyChild transmissionHIV transmissionAntiretroviral drugsPrevalence regionsHIV preventionHIVFamily planningMore childrenPreventionRisk reductionInjection equipmentSaharan Africa
2011
Experience in international clinical research: the HIV Prevention Trials Network
Sista ND, Karim Q, Hinson K, Donnell D, Eshleman SH, Vermund SH. Experience in international clinical research: the HIV Prevention Trials Network. Clinical Investigation 2011, 1: 1609-1618. PMID: 22348195, PMCID: PMC3281583, DOI: 10.4155/cli.11.156.Peer-Reviewed Original ResearchHIV Prevention Trials NetworkCombination antiretroviral therapyHIV transmissionClinical trialsPrevention strategiesTrials NetworkHPTN 052 studyOpiate agonist therapySerodiscordant sexual partnersHIV testing ratesPre-exposure prophylaxisHIV prevention strategiesPivotal efficacy trialsInjection drug usersHigh-risk behaviorsPublic health policyAgonist therapyAntiretroviral therapyHIV seroconversionInfected partnerMiddle-income countriesTrial feasibilityAntiretroviral drugsHPTN 068Efficacy trials
2010
Combination HIV Prevention: Significance, Challenges, and Opportunities
Kurth AE, Celum C, Baeten JM, Vermund SH, Wasserheit JN. Combination HIV Prevention: Significance, Challenges, and Opportunities. Current HIV/AIDS Reports 2010, 8: 62-72. PMID: 20941553, PMCID: PMC3036787, DOI: 10.1007/s11904-010-0063-3.Peer-Reviewed Original ResearchConceptsHIV prevention strategiesHIV transmissionPrevention strategiesPopulation-level HIV transmissionBehavioral risk reductionEvidence-based strategiesNumber of interventionsAntiretroviral medicationsHIV serostatusPrevention packageUninfected personsEpidemiologic profileHIV pandemicMale circumcisionNeedle exchangeEffective interventionsTarget populationInterventionRisk reductionMeasurable reductionPopulation levelDiverse subgroupsMedicationsSerostatusHIV
2009
HIV-prevention science at a crossroads: advances in reducing sexual risk
Vermund SH, Allen KL, Karim QA. HIV-prevention science at a crossroads: advances in reducing sexual risk. Current Opinion In HIV And AIDS 2009, 4: 266-273. PMID: 19532063, PMCID: PMC2995247, DOI: 10.1097/coh.0b013e32832c91dd.Peer-Reviewed Original ResearchConceptsRandomized clinical trialsSexual transmissionPrevention strategiesEvidence-based prevention strategiesMale circumcision trialHIV prevention scienceNew prevention toolsSpread of HIVStructural risk factorsPRO 2000Circumcision trialHIV incidenceSyndromic managementRisk factorsClinical trialsMicrobicide trialsPrevention interventionsHIVPrevention benefitsSexual riskPrevention toolTrialsCombination strategiesMore yearsGlobal pandemic
2007
Use of Traditional Medicine among Pregnant Women in Lusaka, Zambia
Banda Y, Chapman V, Goldenberg RL, Stringer JS, Culhane JF, Sinkala M, Vermund SH, H. B. Use of Traditional Medicine among Pregnant Women in Lusaka, Zambia. Journal Of Alternative And Complementary Medicine 2007, 13: 123-128. PMID: 17309386, DOI: 10.1089/acm.2006.6225.Peer-Reviewed Original ResearchMeSH KeywordsAdultClinical Trials as TopicFemaleHealth BehaviorHealth Knowledge, Attitudes, PracticeHIV InfectionsHumansMaternal BehaviorMaternal Health ServicesMedicine, African TraditionalPatient Acceptance of Health CarePregnancyPregnancy Complications, InfectiousPrevalenceSeroepidemiologic StudiesSurveys and QuestionnairesZambiaConceptsPregnant womenTraditional healersTraditional medicineHuman immunodeficiency virus (HIV) prevention strategiesWorse medical careHealth care providersTraditional medicine usePublic health systemAntiretroviral regimensCurrent pregnancyMedical regimenHIV transmissionMedicine useHIV knowledgeClinical trialsPostpartum questionnaireCare providersPrevention strategiesSex partnersMedical carePrior useHealth systemDry sexPregnancyWomen
2004
Personal Risk Perception, HIV Knowledge and Risk Avoidance Behavior, and Their Relationships to Actual HIV Serostatus in an Urban African Obstetric Population
Stringer EM, Sinkala M, Kumwenda R, Chapman V, Mwale A, Vermund SH, Goldenberg RL, Stringer JS. Personal Risk Perception, HIV Knowledge and Risk Avoidance Behavior, and Their Relationships to Actual HIV Serostatus in an Urban African Obstetric Population. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2004, 35: 60-66. PMID: 14707794, PMCID: PMC2745978, DOI: 10.1097/00126334-200401010-00009.Peer-Reviewed Original ResearchConceptsHIV infectionPregnant womenPersonal risk perceptionSexual partnersEffective HIV prevention strategiesActual HIV statusUnselected pregnant womenLarge clinical trialsHigh HIV seroprevalenceHIV prevention strategiesKnowledge of HIVGreatest risk factorPopulation-based strategiesLifetime sexual partnersObstetric populationHIV seroprevalenceHIV serostatusHIV statusPostpartum womenHIV knowledgeRisk factorsClinical trialsLower riskHIVPrevention strategies
2002
Effect of nevirapine toxicity on choice of perinatal HIV prevention strategies.
Stringer JS, Sinkala M, Rouse DJ, Goldenberg RL, Vermund SH. Effect of nevirapine toxicity on choice of perinatal HIV prevention strategies. American Journal Of Public Health 2002, 92: 365-6. PMID: 11867311, PMCID: PMC1447080, DOI: 10.2105/ajph.92.3.365.Peer-Reviewed Original Research
2000
Cost-Effective Use of Nevirapine to Prevent Vertical HIV Transmission in Sub-Saharan Africa
Stringer J, Rouse D, Vermund S, Goldenberg R, Sinkala M, Stinnett A. Cost-Effective Use of Nevirapine to Prevent Vertical HIV Transmission in Sub-Saharan Africa. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2000, 24: 369-377. DOI: 10.1097/00042560-200008010-00012.Peer-Reviewed Original ResearchConceptsVertical HIV transmissionHIV transmissionPrenatal carePrevention strategiesEffects of NVPModest clinical efficacyOptimal prevention strategiesGreater health gainsDecision analysis modelNevirapine administrationNVP administrationPrenatal visitPreventive therapyStandard therapyClinical efficacySaharan AfricaMass therapyPrenatal strategiesClinical assessmentPrior enrollmentTherapyCost-effective useHealth gainsWomenSerostatusCost-Effective Use of Nevirapine to Prevent Vertical HIV Transmission in Sub-Saharan Africa
Stringer J, Rouse D, Vermund S, Goldenberg R, Sinkala M, Stinnett A. Cost-Effective Use of Nevirapine to Prevent Vertical HIV Transmission in Sub-Saharan Africa. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2000, 24: 369-377. DOI: 10.1097/00126334-200008010-00010.Peer-Reviewed Original ResearchVertical HIV transmissionHIV transmissionPrenatal carePrevention strategiesEffects of NVPModest clinical efficacyOptimal prevention strategiesGreater health gainsDecision analysis modelNevirapine administrationNVP administrationPrenatal visitPreventive therapyStandard therapyClinical efficacySaharan AfricaMass therapyPrenatal strategiesClinical assessmentPrior enrollmentTherapyCost-effective useHealth gainsWomenSerostatusCost-effective use of nevirapine to prevent vertical HIV transmission in sub-Saharan Africa.
Stringer J, Rouse D, Vermund S, Goldenberg R, Sinkala M, Stinnett A. Cost-effective use of nevirapine to prevent vertical HIV transmission in sub-Saharan Africa. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2000, 24: 369-77. PMID: 11015154, DOI: 10.1097/00126334-200008010-00012.Peer-Reviewed Original ResearchConceptsVertical HIV transmissionHIV transmissionPrenatal carePrevention strategiesEffects of NVPModest clinical efficacyOptimal prevention strategiesSaharan AfricaGreater health gainsDecision analysis modelNevirapine administrationNVP administrationPrenatal visitPreventive therapyStandard therapyClinical efficacyMass therapyPrenatal strategiesClinical assessmentPrior enrollmentTherapyCost-effective useHealth gainsWomenSerostatus
1990
HIV Antibody in Persons Screened for Syphilis
Schoenbaum EE, Webber MP, Vermund S, Gayle H. HIV Antibody in Persons Screened for Syphilis. Sexually Transmitted Diseases 1990, 17: 190-193. PMID: 2264007, DOI: 10.1097/00007435-199010000-00008.Peer-Reviewed Original ResearchConceptsReactive syphilis serologyOut-patient clinicHIV antibodiesHIV seroprevalenceSyphilis serologyEmergency roomSyphilis serologic testingHigh HIV seroprevalenceAIDS prevention strategiesHIV infectionSerologic testingPediatric clinicSeroprevalence surveyMunicipal HospitalPrevention strategiesActive individualsClinicSerumSerologySeroprevalenceMenAntibodiesWomenNew York CityHIV