2014
Two-Year Death and Loss to Follow-Up Outcomes by Source of Referral to HIV Care for HIV-Infected Patients Initiating Antiretroviral Therapy in Rural Mozambique
Blevins M, José E, Bilhete FR, Vaz LM, Shepherd BE, Audet CM, Vermund SH, Moon TD. Two-Year Death and Loss to Follow-Up Outcomes by Source of Referral to HIV Care for HIV-Infected Patients Initiating Antiretroviral Therapy in Rural Mozambique. AIDS Research And Human Retroviruses 2014, 31: 198-207. PMID: 25381732, PMCID: PMC4532902, DOI: 10.1089/aid.2014.0007.Peer-Reviewed Original ResearchConceptsSource of referralCombination antiretroviral therapyRural Zambézia ProvinceReferral sitesAntiretroviral therapyAntenatal careGeneral outpatient clinicCumulative incidence estimatesAdditional unmeasured factorsCART initiationHIV careHazard ratioPatient characteristicsHIV testingMedian ageVoluntary counselingCox regressionOutpatient clinicKaplan-MeierPatient populationMedication pickupPatient outcomesInpatient careLTFUIncidence estimatesPoor Clinical Outcomes for HIV Infected Children on Antiretroviral Therapy in Rural Mozambique: Need for Program Quality Improvement and Community Engagement
Vermund SH, Blevins M, Moon TD, José E, Moiane L, Tique JA, Sidat M, Ciampa PJ, Shepherd BE, Vaz LM. Poor Clinical Outcomes for HIV Infected Children on Antiretroviral Therapy in Rural Mozambique: Need for Program Quality Improvement and Community Engagement. PLOS ONE 2014, 9: e110116. PMID: 25330113, PMCID: PMC4203761, DOI: 10.1371/journal.pone.0110116.Peer-Reviewed Original ResearchConceptsCombination antiretroviral therapyAntiretroviral therapyInfant diagnosisClinical outcomesEarly infant diagnosisPoor clinical outcomeYears of ageResource-limited settingsUnknown clinical outcomesCohort mortality ratesQuality improvement effortsART initiationCART initiationRural MozambiqueHIV servicesAdults 15HIV prevalenceKaplan-MeierHigher hemoglobinMedication pickupClinical dataOutcome treatmentNational guidelinesCase findingZambézia Province
2013
Impact of HIV drug resistance on virologic and immunologic failure and mortality in a cohort of patients on antiretroviral therapy in China
Liao L, Xing H, Su B, Wang Z, Ruan Y, Wang X, Liu Z, Lu Y, Yang S, Zhao Q, Vermund SH, Chen RY, Shao Y. Impact of HIV drug resistance on virologic and immunologic failure and mortality in a cohort of patients on antiretroviral therapy in China. AIDS 2013, 27: 1815-1824. PMID: 23803794, PMCID: PMC3694318, DOI: 10.1097/qad.0b013e3283611931.Peer-Reviewed Original ResearchConceptsCombination antiretroviral therapyHIV drug resistanceImmunologic failureHigh mortalityVirologic failureAntiretroviral therapyEmergence of HIVDRBaseline CD4 cell countDrug resistanceCD4 cell countCohort of patientsSecond-line drugsEnd of studyProportional hazards modelRural Chinese countiesHIVDR mutationsMedian timePatient adherenceKaplan-MeierChinese patientsRisk factorsHazards modelPatientsCell countMortality
2012
Addressing Poor Retention of Infants Exposed to HIV
Ciampa PJ, Tique JA, Jumá N, Sidat M, Moon TD, Rothman RL, Vermund SH. Addressing Poor Retention of Infants Exposed to HIV. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2012, 60: e46-e52. PMID: 22622077, PMCID: PMC3587032, DOI: 10.1097/qai.0b013e31824c0267.Peer-Reviewed Original ResearchConceptsEarly infant diagnosisMother/infant pairsInfant pairsEnhanced referralProportion of HIVDays of lifePhase 2 groupProcess of referralLow-resource countriesPhase 2Phase 1Quality improvement effortsHIV carePostpartum dischargeInfant diagnosisAdjusted analysisCox regressionKaplan-MeierDistrict hospitalMedical recordsMAIN OUTCOMEQuality improvement methodsHIVInfantsReferral