2014
Current drug use and lack of HIV virologic suppression: point-of-care urine drug screen versus self-report
Qian HZ, Mitchell VJ, Bebawy S, Cassell H, Perez G, McGowan CC, Sterling TR, Vermund SH, D’Aquila R, Hulgan T. Current drug use and lack of HIV virologic suppression: point-of-care urine drug screen versus self-report. BMC Infectious Diseases 2014, 14: 508. PMID: 25234368, PMCID: PMC4175271, DOI: 10.1186/1471-2334-14-508.Peer-Reviewed Original ResearchConceptsUrine drug screensCurrent drug usePositive urine drug screenComputer Assisted Self-InterviewVirologic suppressionDrug useAntiretroviral therapyDrug screensNegative urine drug screensHigher CD4 countsHIV disease progressionRoutine clinic visitsHIV virologic suppressionCross-sectional studyLower self-reported ratesSelf-reported ratesCD4 countClinic visitsPrognostic informationDisease progressionCaucasian raceART usersLower likelihoodResultsAbout halfSelf interview
2013
Impact of Definitions of Loss to Follow-up on Estimates of Retention, Disease Progression, and Mortality: Application to an HIV Program in Mozambique
Shepherd BE, Blevins M, Vaz LM, Moon TD, Kipp AM, José E, Ferreira FG, Vermund SH. Impact of Definitions of Loss to Follow-up on Estimates of Retention, Disease Progression, and Mortality: Application to an HIV Program in Mozambique. American Journal Of Epidemiology 2013, 178: 819-828. PMID: 23785113, PMCID: PMC3755641, DOI: 10.1093/aje/kwt030.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virusVisit scheduleKaplan-Meier techniqueRate of mortalityAntiretroviral therapyCumulative incidenceTreatment initiationEstimates of retentionImmunodeficiency syndromeImmunodeficiency virusHIV programsChronic diseasesDisease progressionPatient retentionImpact of definitionsHIV literatureClinical encountersStudy outcomesMortalityAIDSLTFDeathInformative censoringProgram evaluationStudy conclusions
2012
Prevention, Detection, and Treatment of Coinfections: A Priority in Human Immunodeficiency Virus–Infected Persons to Reduce Viral Load and Consequent Disease Progression and Transmission : Comment on “Effect of Early Syphilis Infection on Plasma Viral Load and CD4 Cell Count in Human Immunodeficiency Virus–Infected Men”
Vermund SH. Prevention, Detection, and Treatment of Coinfections: A Priority in Human Immunodeficiency Virus–Infected Persons to Reduce Viral Load and Consequent Disease Progression and Transmission : Comment on “Effect of Early Syphilis Infection on Plasma Viral Load and CD4 Cell Count in Human Immunodeficiency Virus–Infected Men”. JAMA Internal Medicine 2012, 172: 1243-1244. PMID: 22824925, DOI: 10.1001/archinternmed.2012.3770.Peer-Reviewed Original Research
2008
Impact of small reductions in plasma HIV RNA levels on the risk of heterosexual transmission and disease progression
Modjarrad K, Chamot E, Vermund SH. Impact of small reductions in plasma HIV RNA levels on the risk of heterosexual transmission and disease progression. AIDS 2008, 22: 2179-2185. PMID: 18832881, PMCID: PMC2661869, DOI: 10.1097/qad.0b013e328312c756.Peer-Reviewed Original ResearchConceptsRisk of progressionHeterosexual transmissionDisease progressionHIV RNALog10 incrementAntiretroviral therapyPlasma HIV RNA levelsGreater riskTreatment of coinfectionHIV RNA levelsHIV viral loadViral load changesHIV-1 RNARelative risk estimatesHIV loadAdjunctive careViral loadPlasma levelsHeterosexual contactWorld's HIVAnnual riskHIVAdult populationViral transmissionRisk estimates
2007
A randomized trial of the intrauterine contraceptive device vs hormonal contraception in women who are infected with the human immunodeficiency virus
Stringer EM, Kaseba C, Levy J, Sinkala M, Goldenberg RL, H. B, Matongo I, Vermund SH, Mwanahamuntu M, Stringer JS. A randomized trial of the intrauterine contraceptive device vs hormonal contraception in women who are infected with the human immunodeficiency virus. American Journal Of Obstetrics And Gynecology 2007, 197: 144.e1-144.e8. PMID: 17689627, PMCID: PMC2730754, DOI: 10.1016/j.ajog.2007.03.031.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virusIntrauterine contraceptive devicePelvic inflammatory diseaseHormonal contraceptionImmunodeficiency virusInflammatory diseasesDisease progressionContraceptive deviceRapid HIV disease progressionHIV disease progressionClinical disease progressionUrgent further studyCopper intrauterine contraceptive deviceContraceptionWomenFurther studiesDiseaseProgressionVirusPostpartumTrials
2006
Factors Associated with Delayed Initiation of HIV Medical Care Among Infected Persons Attending a Southern HIV/AIDS Clinic
Krawczyk CS, Funkhouser E, Kilby JM, Kaslow RA, Bey AK, Vermund SH. Factors Associated with Delayed Initiation of HIV Medical Care Among Infected Persons Attending a Southern HIV/AIDS Clinic. Southern Medical Journal 2006, 99: 472-481. PMID: 16711309, PMCID: PMC2761649, DOI: 10.1097/01.smj.0000215639.59563.83.Peer-Reviewed Original ResearchConceptsHIV medical careHIV diagnosisHIV/AIDS outpatient clinicMedical careHuman immunodeficiency virus (HIV) diagnosisHIV/AIDS clinicAIDS outpatient clinicMedicaid insurance coverageAIDS clinicMale sexOutpatient clinicDisease progressionDelayed initiationClinical careInfected personsPatientsCareInsurance coverageDiagnosisHIVVirus diagnosisClinicPresentationAIDSProgression
1998
Serum Retinol and HIV-1 RNA Viral Load in Rapid and Slow Progressors
Camp W, Allen S, Alvarez J, Jolly P, Weiss H, Phillips J, Karita E, Serufilira A, Vermund S. Serum Retinol and HIV-1 RNA Viral Load in Rapid and Slow Progressors. JAIDS Journal Of Acquired Immune Deficiency Syndromes 1998, 18: 401-406. PMID: 9704954, DOI: 10.1097/00042560-199808010-00022.Peer-Reviewed Original ResearchConceptsSerum retinol levelsHIV-1 RNA viral loadLow viral loadLow serum retinol levelsRNA viral loadSlow progressorsRetinol levelsViral loadHIV serologySerum retinolDisease progressionFirst HIV-positive testHigher serum retinol levelsAsymptomatic HIV infectionHigh HIV loadLow serum retinolSerum retinol valuesHIV disease progressionHIV-positive testHigh viral loadThirty HIVHIV loadHIV infectionRapid progressorsSerum vitaminSerum Retinol and HIV-1 RNA Viral Load in Rapid and Slow Progressors
Camp W, Allen S, Alvarez J, Jolly P, Weiss H, Phillips J, Karita E, Serufilira A, Vermund S. Serum Retinol and HIV-1 RNA Viral Load in Rapid and Slow Progressors. JAIDS Journal Of Acquired Immune Deficiency Syndromes 1998, 18: 21-26. PMID: 9593454, DOI: 10.1097/00042560-199805010-00004.Peer-Reviewed Original ResearchConceptsSerum retinol levelsLow viral loadHIV-1 RNA viral loadLow serum retinol levelsRNA viral loadSlow progressorsRetinol levelsViral loadHIV serologySerum retinolDisease progressionFirst HIV-positive testHigher serum retinol levelsAsymptomatic HIV infectionHigh HIV loadLow serum retinolSerum retinol valuesHIV disease progressionHIV-positive testHigh viral loadThirty HIVHIV loadHIV infectionRapid progressorsSerum vitamin