2022
Antiretroviral therapy resistance mutations among HIV infected people in Kazakhstan
Mukhatayeva A, Mustafa A, Dzissyuk N, Issanov A, Mukhatayev Z, Bayserkin B, Vermund SH, Ali S. Antiretroviral therapy resistance mutations among HIV infected people in Kazakhstan. Scientific Reports 2022, 12: 17195. PMID: 36229577, PMCID: PMC9562405, DOI: 10.1038/s41598-022-22163-7.Peer-Reviewed Original Research
2017
Mobility and Clinic Switching Among Postpartum Women Considered Lost to HIV Care in South Africa
Clouse K, Vermund SH, Maskew M, Lurie MN, MacLeod W, Malete G, Carmona S, Sherman G, Fox MP. Mobility and Clinic Switching Among Postpartum Women Considered Lost to HIV Care in South Africa. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2017, 74: 383-389. PMID: 28225717, PMCID: PMC5324708, DOI: 10.1097/qai.0000000000001284.Peer-Reviewed Original ResearchConceptsHIV careNational Health Laboratory Service databaseLow CD4 cell countsNational Antiretroviral Therapy ProgramCD4 cell countObservational cohort studyAntiretroviral therapy programsAntiretroviral therapyCohort studyPostpartum womenPublic clinicsService databaseCell countTherapy programCareWomenLTFUClinicOne-thirdDaysPatientsPregnancyTherapy
2016
Patient and Provider Satisfaction With a Comprehensive Strategy to Improve Prevention of Mother-to-Child HIV Transmission Services in Rural Nigeria
Boehmer A, Audet CM, Blevins M, Gebi UI, Wester CW, Vermund SH, Aliyu MH. Patient and Provider Satisfaction With a Comprehensive Strategy to Improve Prevention of Mother-to-Child HIV Transmission Services in Rural Nigeria. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2016, 72: s117-s123. PMID: 27355498, PMCID: PMC5113240, DOI: 10.1097/qai.0000000000001058.Peer-Reviewed Original ResearchConceptsPrevention of motherProvider satisfactionPatient satisfactionWeeks postpartumControl armIntervention sitesChild HIV transmission servicesChild HIV transmission rateMother-infant careCD4 cell countHIV transmission ratesCluster-randomized trialTotal patient satisfactionAntiretroviral therapyHIV careChild transmissionPrescribed treatmentClinician satisfactionHealth personnelLower cadre workersCell countHealth problemsMale involvementProvider rolesProviders' ability
2015
Prevalence and risk factors of cervical squamous intraepithelial lesions among HIV-infected women in Dar es Salaam, Tanzania
Liu E, McCree R, Mtisi E, Fawzi WW, Aris E, Lema IA, Hertzmark E, Chalamilla G, Li N, Vermund SH, Spiegelman D. Prevalence and risk factors of cervical squamous intraepithelial lesions among HIV-infected women in Dar es Salaam, Tanzania. International Journal Of STD & AIDS 2015, 27: 219-225. PMID: 25957324, PMCID: PMC11340030, DOI: 10.1177/0956462415584466.Peer-Reviewed Original ResearchConceptsCervical squamous intraepithelial lesionsSquamous intraepithelial lesionsHIV disease stageCell countIntraepithelial lesionsDisease stageHigh-grade squamous intraepithelial lesionsAdvanced HIV disease stageCervical cancer prevention servicesLow CD4 cell countsCD4 cell countCancer prevention servicesCross-sectional studyResource-limited settingsCervical inflammationLow CD4Median CD4HIV careMedian ageCervical screeningPapanicolaou smearsRisk factorsTreatment clinicsPrevention servicesHIVEnrolment trends in a comprehensive HIV programme in rural north-central Nigeria: improved care indices, but declining quality of clinical data over time
Aliyu MH, Blevins M, Arinze F, Megazzini KM, Bussell S, Dunlap J, Odoh C, Gebi UI, Muhammad MY, Shepherd BE, Audet CM, Vermund SH, Wester CW. Enrolment trends in a comprehensive HIV programme in rural north-central Nigeria: improved care indices, but declining quality of clinical data over time. Pathogens And Global Health 2015, 109: 75-83. PMID: 25822098, PMCID: PMC4571821, DOI: 10.1179/2047773215y.0000000007.Peer-Reviewed Original ResearchConceptsComprehensive HIV programsHIV programsComprehensive HIV/AIDS servicesCell countAdvanced clinical diseaseClinical stage INorth Central NigeriaHIV/AIDS servicesRural North-Central NigeriaQuality improvement effortsMedian CD4Clinical stagingMedian ageHIV servicesCare indexClinical dataClinical diseaseStage IAIDS servicesPatientsWindow periodHemoglobin dataClinical servicesEnrollment yearCells/
2013
Impact of HIV drug resistance on virologic and immunologic failure and mortality in a cohort of patients on antiretroviral therapy in China
Liao L, Xing H, Su B, Wang Z, Ruan Y, Wang X, Liu Z, Lu Y, Yang S, Zhao Q, Vermund SH, Chen RY, Shao Y. Impact of HIV drug resistance on virologic and immunologic failure and mortality in a cohort of patients on antiretroviral therapy in China. AIDS 2013, 27: 1815-1824. PMID: 23803794, PMCID: PMC3694318, DOI: 10.1097/qad.0b013e3283611931.Peer-Reviewed Original ResearchConceptsCombination antiretroviral therapyHIV drug resistanceImmunologic failureHigh mortalityVirologic failureAntiretroviral therapyEmergence of HIVDRBaseline CD4 cell countDrug resistanceCD4 cell countCohort of patientsSecond-line drugsEnd of studyProportional hazards modelRural Chinese countiesHIVDR mutationsMedian timePatient adherenceKaplan-MeierChinese patientsRisk factorsHazards modelPatientsCell countMortality
2012
Availability of Volunteer-Led Home-Based Care System and Baseline Factors as Predictors of Clinical Outcomes in HIV-Infected Patients in Rural Zambia
Estopinal CB, van Dijk JH, Sitali S, Stewart H, Davidson MA, Spurrier J, Vermund SH. Availability of Volunteer-Led Home-Based Care System and Baseline Factors as Predictors of Clinical Outcomes in HIV-Infected Patients in Rural Zambia. PLOS ONE 2012, 7: e49564. PMID: 23236351, PMCID: PMC3517597, DOI: 10.1371/journal.pone.0049564.Peer-Reviewed Original ResearchConceptsBody mass indexHome-based careLower body mass indexART initiationAntiretroviral therapyUnfavorable outcomeTreatment outcomesFavorable outcomeRural Southern ProvinceCell countRetrospective cohort studyImproved treatment outcomesEligible patientsHBC programmesLow CD4HIV careAdherence counselingCohort studyDate of birthBaseline factorsMedical chartsBivariable analysisClinical outcomesMass indexMultivariable analysisPrevention, Detection, and Treatment of Coinfections: A Priority in Human Immunodeficiency Virus–Infected Persons to Reduce Viral Load and Consequent Disease Progression and Transmission : Comment on “Effect of Early Syphilis Infection on Plasma Viral Load and CD4 Cell Count in Human Immunodeficiency Virus–Infected Men”
Vermund SH. Prevention, Detection, and Treatment of Coinfections: A Priority in Human Immunodeficiency Virus–Infected Persons to Reduce Viral Load and Consequent Disease Progression and Transmission : Comment on “Effect of Early Syphilis Infection on Plasma Viral Load and CD4 Cell Count in Human Immunodeficiency Virus–Infected Men”. JAMA Internal Medicine 2012, 172: 1243-1244. PMID: 22824925, DOI: 10.1001/archinternmed.2012.3770.Peer-Reviewed Original Research
2007
Prevalence and distribution of HPV genotypes among HIV-infected women in Zambia
Sahasrabuddhe VV, Mwanahamuntu MH, Vermund SH, Huh WK, Lyon MD, Stringer JS, Parham GP. Prevalence and distribution of HPV genotypes among HIV-infected women in Zambia. British Journal Of Cancer 2007, 96: 1480-1483. PMID: 17437020, PMCID: PMC2360194, DOI: 10.1038/sj.bjc.6603737.Peer-Reviewed Original ResearchConceptsSquamous cell carcinomaHuman papillomavirusHPV 16High-grade squamous intraepithelial lesionsDistribution of HPVHigh-risk HPV typesCervical cytological abnormalitiesTertiary care centerSquamous intraepithelial lesionsNon-pregnant womenHigh-grade lesionsHigh-risk typesSensitivity of cytologyLiquid-based cytologyHPV-52HPV typesIntraepithelial lesionsProtective immunityCell carcinomaCare centerCytological abnormalitiesHPV assessmentCell countCytologyWomen
2004
Incidence and Risk Factors for Sexually Transmitted Infections among Women in an Alabama HIV Clinic
Monteiro CA, Bachmann LH, Desmond RA, Squires KE, Vermund SH, Hook EW, Schwebke JR, Hoesley CJ. Incidence and Risk Factors for Sexually Transmitted Infections among Women in an Alabama HIV Clinic. AIDS Research And Human Retroviruses 2004, 20: 577-583. PMID: 15242532, DOI: 10.1089/0889222041217437.Peer-Reviewed Original ResearchConceptsT-cell countsNatural history studiesCurable STIsHIV clinicCell countCohort of HIVCells/mm3Primary care settingAge 35 yearsUniversity HIV clinicMean age 35 yearsEntry CD4Higher CD4Incident STIsSTI incidenceMonths of observationClinic appointmentsChlamydial infectionPrimary careRisk factorsCare settingsStudy populationSTIsInfectionIncidence
2000
T-Lymphocyte Subsets in HIV-Infected and High-Risk HIV-Uninfected Adolescents: Retention of Naive T Lymphocytes in HIV-Infected Adolescents
Douglas SD, Rudy B, Muenz L, Starr SE, Campbell DE, Wilson C, Holland C, Crowley-Nowick P, Vermund SH. T-Lymphocyte Subsets in HIV-Infected and High-Risk HIV-Uninfected Adolescents: Retention of Naive T Lymphocytes in HIV-Infected Adolescents. JAMA Pediatrics 2000, 154: 375-380. PMID: 10768676, DOI: 10.1001/archpedi.154.4.375.Peer-Reviewed Original ResearchConceptsHIV-negative youthHuman immunodeficiency virus-infected adolescentsT lymphocyte subsetsNaive CD8Total CD4Immune systemCell countHIV infectionAdolescent careAdolescent Medicine HIV/AIDS Research NetworkHuman immunodeficiency virus (HIV) infectionHealth ProjectActive antiretroviral therapyCohort of HIVPercentage of CD4HIV-negative controlsHIV-positive subjectsImmunodeficiency virus infectionAIDS Research NetworkHigh-risk HIVT lymphocyte responsesHIV-negative adolescentsNaive T lymphocytesMemory cell populationsSignificant increase
1997
Changes in total, CD4+, and CD8+ lymphocytes during pregnancy and 1 year postpartum in human immunodeficiency virus-infected women. The Women and Infants Transmission Study.
Tuomala RE, Kalish LA, Zorilla C, Fox H, Shearer W, Landay A, Vermund SH, Landesman S, Burns D. Changes in total, CD4+, and CD8+ lymphocytes during pregnancy and 1 year postpartum in human immunodeficiency virus-infected women. The Women and Infants Transmission Study. Obstetrics And Gynecology 1997, 89: 967-74. PMID: 9170476, DOI: 10.1016/s0029-7844(97)00129-4.Peer-Reviewed Original ResearchConceptsTotal lymphocyte countFirst postpartum yearLymphocyte countYear postpartumCell countCD8 percentagesNonpregnant cohortLymphocyte subsetsPostpartum yearHuman immunodeficiency virus-infected womenCD4/CD8 ratioInfants Transmission StudyHuman immunodeficiency virusImmediate postpartum periodCD4 percentMean CD4Nonpregnant HIVRelative CD4CD8 ratioAbsolute CD4Lymphocyte parametersNonpregnant womenImmunodeficiency virusPregnant womenPostpartum period
1992
The Effects on Survival of Early Treatment of Human Immunodeficiency Virus Infection
Graham N, Zeger S, Park L, Vermund S, Detels R, Rinaldo C, Phair J. The Effects on Survival of Early Treatment of Human Immunodeficiency Virus Infection. New England Journal Of Medicine 1992, 326: 1037-1042. PMID: 1347907, DOI: 10.1056/nejm199204163261601.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virus (HIV) infectionImmunodeficiency virus infectionDevelopment of AIDSPneumocystis carinii pneumoniaPCP prophylaxisProlong survivalEarly treatmentRelative riskVirus infectionCell countUse of zidovudineUse of prophylaxisDiagnosis of AIDSHIV Type 1HIV-1 infectionBasis of CD4High-risk menInitial disease stateProbability of deathZidovudine usersZidovudine therapyImmunodeficiency syndromeCarinii pneumoniaClinical symptomsProphylaxisCD4+ Lymphocyte Cell Enumeration for Prediction of Clinical Course of Human Immunodeficiency Virus Disease: A Review
Stein D, Korvick J, Vermund S. CD4+ Lymphocyte Cell Enumeration for Prediction of Clinical Course of Human Immunodeficiency Virus Disease: A Review. The Journal Of Infectious Diseases 1992, 165: 352-363. PMID: 1346152, DOI: 10.1093/infdis/165.2.352.Peer-Reviewed Original ResearchConceptsCell countHuman immunodeficiency virus (HIV) diseaseHuman immunodeficiency virus (HIV) infectionIntercurrent viral infectionPractical clinical perspectiveProgressive infectious processImmunodeficiency virus infectionImportant therapeutic decisionsAIDS CommentaryInfluence of drugsT helperClinical courseHIV infectionSurrogate markerTherapeutic decisionsVirus infectionInfectious processViral infectionCD4Clinical perspectiveEnd stageInfectionNational InstituteVirus diseaseCount