2023
Decidualization dampens toll-like receptor mediated inflammatory responses in human endometrial stromal cells by upregulating IκBα
Tong M, Scott J, Whirledge S, Abrahams V. Decidualization dampens toll-like receptor mediated inflammatory responses in human endometrial stromal cells by upregulating IκBα. Journal Of Reproductive Immunology 2023, 159: 103988. PMID: 37451159, PMCID: PMC10530124, DOI: 10.1016/j.jri.2023.103988.Peer-Reviewed Original ResearchMeSH KeywordsDeciduaEndometriumFemaleHumansNF-KappaB Inhibitor alphaPregnancyStromal CellsToll-Like ReceptorsConceptsEndometrial stromal cellsInflammatory responseStromal cellsHuman endometrial stromal cellsToll-like receptor signalingSex hormone levelsMenstrual cycle stageToll-like receptorsImmune response changesViral double-stranded RNAHuman EnSCsEndometrial responseProinflammatory cytokinesSuccessful pregnancyMenstrual cycleHuman endometriumHormone levelsMajor cell typesImmune responseNFκB p65Viral infectionDecidualizationBacterial lipopolysaccharideReceptor signalingBacterial components
2010
Glucocorticoids, stress, and fertility.
Whirledge S, Cidlowski JA. Glucocorticoids, stress, and fertility. Minerva Endocrinologica 2010, 35: 109-25. PMID: 20595939, PMCID: PMC3547681.Peer-Reviewed Original ResearchConceptsLevels of glucocorticoidsGonadal functionNormal brain developmentTestes/ovariesLevels of glucoseLife-long effectsFetal exposureMaternal exposureStress-related behaviorsAdrenal functionExogenous glucocorticoidsAdrenal axisGonadal axisNeuroendocrine functionGlucocorticoid inhibitionAnatomical sitesPrenatal stressElevated glucocorticoidsGlucocorticoidsPituitary glandReproductive functionBrain developmentStressful challengesFat breakdownMultiple tissues