2019
Bone-marrow-derived endothelial progenitor cells contribute to vasculogenesis of pregnant mouse uterus†
Tal R, Dong D, Shaikh S, Mamillapalli R, Taylor HS. Bone-marrow-derived endothelial progenitor cells contribute to vasculogenesis of pregnant mouse uterus†. Biology Of Reproduction 2019, 100: 1228-1237. PMID: 30601943, PMCID: PMC6497522, DOI: 10.1093/biolre/ioy265.Peer-Reviewed Original ResearchConceptsEndothelial progenitor cellsPregnant uterusImplantation sitesPregnant miceBM-derived endothelial progenitor cellsProgenitor cellsEarly pregnant uterusUterine implantation sitesContribution of BMNew blood vesselsEndometrial growthBM transplantationEndothelial cell populationEndometrial vasculaturePregnancy maintenanceDecidual vasculatureMouse recipientsGestational dayVascular endotheliumEndothelial-specific promoterBone marrowTransgenic miceMouse deciduaFlow cytometryMice
2010
Effects of Hypoxia-Inducible Factor-1α Overexpression in Pregnant Mice Possible Implications for Preeclampsia and Intrauterine Growth Restriction
Tal R, Shaish A, Barshack I, Polak-Charcon S, Afek A, Volkov A, Feldman B, Avivi C, Harats D. Effects of Hypoxia-Inducible Factor-1α Overexpression in Pregnant Mice Possible Implications for Preeclampsia and Intrauterine Growth Restriction. American Journal Of Pathology 2010, 177: 2950-2962. PMID: 20952590, PMCID: PMC2993274, DOI: 10.2353/ajpath.2010.090800.Peer-Reviewed Original ResearchConceptsIntrauterine growth restrictionHIF-1αControl micePregnant miceGrowth restrictionFetal intrauterine growth restrictionSoluble vascular endothelial growth factor receptor-1Vascular endothelial growth factor receptor 1Serum sFlt-1Elevated liver enzymesLiver enzyme levelsMicroangiopathic hemolytic anemiaPregnancy-specific disorderHypoxia-inducible factor-1αComplete blood countGestational day 8Growth factor receptor 1HIF-1α overexpressionFactor receptor 1Hypoxia-inducible factorPlacental weightPregnant controlsSoluble endoglinBlood pressureSignificant anemia