The Role of Hypoxia and Hypoxia-Inducible Factor-1Alpha in Preeclampsia Pathogenesis
Tal R. The Role of Hypoxia and Hypoxia-Inducible Factor-1Alpha in Preeclampsia Pathogenesis. Biology Of Reproduction 2012, 87: 134, 1-8. PMID: 23034156, DOI: 10.1095/biolreprod.112.102723.Peer-Reviewed Original ResearchConceptsSoluble fms-like tyrosine kinase-1Pathogenesis of preeclampsiaRole of hypoxiaSoluble endoglinAngiotensin II receptor type IFms-like tyrosine kinase-1Spiral artery remodelingTyrosine kinase-1Hypoxia-inducible factor-1alphaReceptor type IHypoxia-inducible factorMaternal manifestationsPutative culpritsFetal morbiditySymptomatic therapyArtery remodelingPlacental hypoxiaCascade of eventsEndothelin-1Preeclampsia pathogenesisDisease manifestationsPossible molecular linkPreeclampsiaEffective preventionPathogenesisPreeclampsia-associated soluble endoglin (sENG) is decreased in polycystic ovarian syndrome (PCOS) leading to transforming growth factor (TGF)-B1 dysregulation during controlled ovarian stimulation
Tal R, Seifer D, Shohat-Tal A, Grazi R, Malter H. Preeclampsia-associated soluble endoglin (sENG) is decreased in polycystic ovarian syndrome (PCOS) leading to transforming growth factor (TGF)-B1 dysregulation during controlled ovarian stimulation. Fertility And Sterility 2012, 98: s84. DOI: 10.1016/j.fertnstert.2012.07.304.Peer-Reviewed Original Research