2018
Measurement of compensatory reserve predicts racial differences in tolerance to simulated hemorrhage in women
Wenner MM, Hinds KA, Howard JT, Nawn CD, Stachenfeld NS, Convertino VA. Measurement of compensatory reserve predicts racial differences in tolerance to simulated hemorrhage in women. Journal Of Trauma And Acute Care Surgery 2018, 85: s77-s83. PMID: 29443858, PMCID: PMC6023758, DOI: 10.1097/ta.0000000000001837.Peer-Reviewed Original ResearchConceptsLower body negative pressureBeat blood pressureHg lower body negative pressureCentral blood volumeCompensatory reserve measurementHeart rateWhite womenBlood volumeProgressive lower body negative pressureInadequate tissue oxygenationSigns/symptomsBody negative pressureProgressive central hypovolemiaRacial differencesStandard vital signsAfrican American womenBlood pressureHemodynamic decompensationAA womenCentral hypovolemiaRetrospective analysisTissue oxygenationRate of declineHemorrhageNegative pressure
2017
Measurement of the Compensatory Reserve Predicts Racial Differences in Orthostatic Tolerance
Wenner M, Hinds K, Howard J, Nawn C, Stachenfeld N, Convertino V. Measurement of the Compensatory Reserve Predicts Racial Differences in Orthostatic Tolerance. The FASEB Journal 2017, 31: 1087.2-1087.2. DOI: 10.1096/fasebj.31.1_supplement.1087.2.Peer-Reviewed Original ResearchLower body negative pressureBeat blood pressureCompensatory reserve indexMmHg lower body negative pressureCaucasian womenStroke volumeHeart rateOrthostatic toleranceAA womenOrthostatic stressProgressive lower body negative pressureCentral blood volumeBody negative pressureProgressive central hypovolemiaRacial differencesTraditional vital signsUS Army Medical ResearchAfrican American womenBlood pressure waveformBlood pressureHemodynamic decompensationCentral hypovolemiaLBNP stageArmy Medical ResearchBlood volume
2015
Peripheral Microvascular Vasodilatory Response to Estradiol and Genistein in Women with Insulin Resistance
Wenner MM, Taylor HS, Stachenfeld NS. Peripheral Microvascular Vasodilatory Response to Estradiol and Genistein in Women with Insulin Resistance. Microcirculation 2015, 22: 391-399. PMID: 25996650, PMCID: PMC4506724, DOI: 10.1111/micc.12208.Peer-Reviewed Original ResearchConceptsL-NMMAMicrovascular vasodilationHealthy womenVasodilatory responsivenessLocal cutaneous heatingMicrovascular vasodilatory functionMicrovascular vasodilatory responsesBeat blood pressureHealthy young womenLaser Doppler flowmetryHeat-induced vasodilationMicrovascular responsivenessVascular effectsVasodilatory responseBlood pressureMicrovascular functionVasodilatory functionCutaneous heatingInsulin resistanceCutaneous circulationDoppler flowmetryGEN exposureInteraction of E2VasodilationMicrodialysis perfusion
2013
Mechanisms contributing to low orthostatic tolerance in women: the influence of oestradiol
Wenner MM, Haddadin A, Taylor HS, Stachenfeld NS. Mechanisms contributing to low orthostatic tolerance in women: the influence of oestradiol. The Journal Of Physiology 2013, 591: 2345-2355. PMID: 23401618, PMCID: PMC3650699, DOI: 10.1113/jphysiol.2012.247882.Peer-Reviewed Original ResearchConceptsLow orthostatic toleranceE2 administrationOrthostatic toleranceVascular resistanceBlood pressureStroke volumeHeart rateGonadotrophin-releasing hormone antagonistLevels of LBNPLower central volumeReproductive hormone productionAdministration of E2Peripheral vascular resistanceBeat blood pressureAutonomic cardiovascular regulationLower stroke volumeLower body negative pressure testHeart rate responseInfluence of oestradiolBaroreflex controlTolerant womenHormone antagonistCardiovascular regulationPeripheral vasoconstrictionAutonomic control