2019
Fetal Myocardial Function as Assessed by N-Terminal Fragment Brain Natriuretic Protein in Premature Fetuses Exposed to Intra-amniotic Inflammation
Irani RA, Buhimschi CS, Cross SN, Zhao G, Copel JA, Bhandari V, Buhimschi IA, Bahtiyar MO. Fetal Myocardial Function as Assessed by N-Terminal Fragment Brain Natriuretic Protein in Premature Fetuses Exposed to Intra-amniotic Inflammation. American Journal Of Perinatology 2019, 37: 745-753. PMID: 31121635, DOI: 10.1055/s-0039-1688909.Peer-Reviewed Original ResearchMeSH KeywordsAdultAmniocentesisAmniotic FluidBiomarkersChorioamnionitisEchocardiography, DopplerFemaleFetal BloodFetal HeartHumansInfant, NewbornInfant, PrematureInflammationInterleukin-6MaleMass SpectrometryNatriuretic Peptide, BrainPeptide FragmentsPlacentaPregnancyPremature BirthVentricular Function, LeftConceptsIntra-amniotic infection/inflammationBrain natriuretic proteinAmniotic fluidNT-proBNPTei indexNatriuretic proteinVentricular functionFetal exposureCord bloodCord IL-6Intra-amniotic inflammationFetal myocardial functionInfection/inflammationBlood NT-proBNPFetal heart functionNT-proBNP immunoassaysEnzyme-linked immunosorbentGestational agePremature fetusesFetal echocardiogramIL-6Circulatory levelsMyocardial functionHeart functionFetuses
1999
Nitric Oxide: A Clinically Important Amniotic Fluid Markerto Distinguish Between Intra-Amniotic Mycoplasma and Non-Mycoplasma Infections
Hsu C, Aversa K, Lu L, Meaddough E, Jones D, Bahado-Singh R, Copel J, Lee I. Nitric Oxide: A Clinically Important Amniotic Fluid Markerto Distinguish Between Intra-Amniotic Mycoplasma and Non-Mycoplasma Infections. American Journal Of Perinatology 1999, 16: 161-166. PMID: 10458527, DOI: 10.1055/s-2007-993851.Peer-Reviewed Original ResearchConceptsAmniotic fluid testsIntra-amniotic infectionInterleukin-6Mycoplasma infectionLeukocyte countFluid testsAmniotic fluid creatinine levelsAmniotic fluid glucose levelNitric oxide metabolite concentrationsPositive amniotic fluid cultureInterleukin-6 concentrationsManagement of patientsAmniotic fluid concentrationsAmniotic fluid leukocyte countsAmniotic fluid cultureClinical characteristicsCreatinine levelsPregnant womenClinical managementFluid cultureGlucose levelsClinical importanceUseful markerGriess reagentInfection
1998
Elevated amniotic fluid levels of leukemia inhibitory factor, interleukin 6, and interleukin 8 in intra-amniotic infection
Hsu C, Meaddough E, Aversa K, Hong S, Lu L, Jones D, Copel J. Elevated amniotic fluid levels of leukemia inhibitory factor, interleukin 6, and interleukin 8 in intra-amniotic infection. American Journal Of Obstetrics And Gynecology 1998, 179: 1267-1270. PMID: 9822513, DOI: 10.1016/s0002-9378(98)70144-9.Peer-Reviewed Original ResearchConceptsIntra-amniotic infectionAmniotic fluid levelsLeukemia inhibitory factorInterleukin-6Interleukin-8Fluid levelsInhibitory factorCreatinine levelsPregnant womenPositive amniotic fluid culture resultsAmniotic fluid creatinine levelsElevated amniotic fluid levelsAmniotic fluid culture resultsAmniotic fluid testsEnzyme-linked immunoassayPreterm contractionsPremature rupturePrognostic importanceLeukocyte countSignificant elevationAmniotic fluidMedian levelsCulture resultsInfectionGram stainElevated amniotic fluid nitric oxide metabolites and interleukin-6 in intra-amniotic infection.
Hsu C, Meaddough E, Hong S, Aversa K, Lu L, Copel J. Elevated amniotic fluid nitric oxide metabolites and interleukin-6 in intra-amniotic infection. Reproductive Sciences 1998, 5: 21-4. PMID: 9501294, DOI: 10.1016/s1071-5576(97)00099-3.Peer-Reviewed Original ResearchConceptsAmniotic fluid nitric oxide metabolitesIntra-amniotic infectionNitric oxide metabolitesLeukocyte esterase activityIL-6Oxide metabolitesLeukocyte countInterleukin-6Glucose levelsRank correlation testAmniotic fluid creatinine levelsAmniotic fluid glucose levelAmniotic fluid IL-6Positive amniotic fluid cultureGram stainIL-6 levelsInterleukin-6 concentrationsIL-6 concentrationsAmniotic fluid leukocyte countsUseful clinical markerMann-Whitney U testEnzyme-linked immunosorbentAmniotic fluid cultureCreatinine levelsGestational age