2014
A novel staging model to classify oesophageal squamous cell carcinoma patients in China
Tan H, Zhang H, Xie J, Chen B, Wen C, Guo X, Zhao Q, Wu Z, Shen J, Wu J, Xu X, Li E, Xu L, Wang X. A novel staging model to classify oesophageal squamous cell carcinoma patients in China. British Journal Of Cancer 2014, 110: 2109-2115. PMID: 24569468, PMCID: PMC3992487, DOI: 10.1038/bjc.2014.101.Peer-Reviewed Original ResearchConceptsESCC patientsClinical variablesStaging systemOesophageal squamous cell carcinoma patientsSurvival analysisSquamous cell carcinoma patientsOesophageal squamous cell carcinomaKaplan-Meier survival analysisCell carcinoma patientsPotential prognostic factorsTNM staging systemSquamous cell carcinomaMetastasis (TNM) staging systemOesophageal carcinomaPrognostic factorsCarcinoma patientsCell carcinomaSame hospitalESCC prognosisPredominant subtypeRisk scoreIndependent cohortPatientsSurvival rateStaging model
2013
NKAIN1–SERINC2 is a functional, replicable and genome-wide significant risk gene region specific for alcohol dependence in subjects of European descent
Zuo L, Wang K, Zhang XY, Krystal JH, Li CS, Zhang F, Zhang H, Luo X. NKAIN1–SERINC2 is a functional, replicable and genome-wide significant risk gene region specific for alcohol dependence in subjects of European descent. Drug And Alcohol Dependence 2013, 129: 254-264. PMID: 23455491, PMCID: PMC3628730, DOI: 10.1016/j.drugalcdep.2013.02.006.Peer-Reviewed Original ResearchConceptsGenome-wide association studiesExpression quantitative loci (eQTL) analysisGene regionMetabolic pathwaysQuantitative loci analysisSNP-expression associationsCis-acting regulatory effectsDiscovery sampleSNP-disease associationsNumerous genesReplication sampleLocus analysisAssociation studiesAssociation analysisRisk SNPsTranscript expressionSNPsRegulatory effectsGenesPathwayEuropean descentExpression