Trophoblast Inclusions Are Significantly Increased in the Placentas of Children in Families at Risk for Autism
Walker CK, Anderson KW, Milano KM, Ye S, Tancredi DJ, Pessah IN, Hertz-Picciotto I, Kliman HJ. Trophoblast Inclusions Are Significantly Increased in the Placentas of Children in Families at Risk for Autism. Biological Psychiatry 2013, 74: 204-211. PMID: 23623455, PMCID: PMC3755347, DOI: 10.1016/j.biopsych.2013.03.006.Peer-Reviewed Original ResearchMeSH KeywordsChild Development Disorders, PervasiveConfidence IntervalsDevelopmental DisabilitiesFamily HealthFemaleHumansInfantLogistic ModelsMaleOdds RatioPlacentaPregnancyRisk FactorsTrophoblastsConceptsElevated riskPlacentas of childrenTrophoblast inclusionsUncomplicated term pregnanciesAutism spectrum disorderPositive likelihood ratioTargeted early interventionsNeurodevelopmental compromiseMultiparous womenTerm pregnancyRisk pregnanciesBiological childrenControl placentasBehavioral symptomsEarly interventionNeurodevelopmental vulnerabilityPlacentaCritical windowRisk statusPregnancyRiskNewbornsChildrenDevelopmental outcomesControl samples