1996
Modulation of leukemia inhibitory factor gene expression and protein biosynthesis in the human fallopian tube
Keltz M, Attar E, Buradagunta S, Olive D, Kliman H, Arici A. Modulation of leukemia inhibitory factor gene expression and protein biosynthesis in the human fallopian tube. American Journal Of Obstetrics And Gynecology 1996, 175: 1611-1619. PMID: 8987949, DOI: 10.1016/s0002-9378(96)70114-x.Peer-Reviewed Original ResearchMeSH KeywordsAdultBlood Physiological PhenomenaCells, CulturedCulture MediaCytokinesEpitheliumFallopian TubesFemaleGene Expression RegulationGrowth InhibitorsGrowth SubstancesHormonesHumansInterleukin-6Leukemia Inhibitory FactorLymphokinesMiddle AgedPregnancyPregnancy, EctopicRNA, MessengerStromal CellsConceptsLeukemia inhibitory factor expressionLeukemia inhibitory factorFallopian tubeInhibitory factorStromal cellsEctopic pregnancyStromal cell culturesGrowth factorMessenger ribonucleic acidLeukemia inhibitory factor gene expressionEctopic implantationFactor expressionTubal ectopic pregnancyEpithelial cellsInterleukin-1 alphaHuman fallopian tubePlatelet-derived growth factorMessenger ribonucleic acid levelsRibonucleic acid levelsFactor gene expressionTubal mucosaMenstrual cycleTNF-alphaTumor necrosisCommon siteThe effect of leukemia inhibitory factor (LIF) on trophoblast differentiation: a potential role in human implantation
Nachtigall MJ, Kliman HJ, Feinberg RF, Olive DL, Engin O, Arici A. The effect of leukemia inhibitory factor (LIF) on trophoblast differentiation: a potential role in human implantation. The Journal Of Clinical Endocrinology & Metabolism 1996, 81: 801-806. PMID: 8636307, DOI: 10.1210/jcem.81.2.8636307.Peer-Reviewed Original ResearchMeSH KeywordsBlotting, NorthernCell DifferentiationCells, CulturedChorionic GonadotropinChorionic Gonadotropin, beta Subunit, HumanEmbryo ImplantationFemaleFibronectinsGene ExpressionGrowth InhibitorsHumansInterleukin-6Leukemia Inhibitory FactorLymphokinesPregnancyProgesteroneRNA, MessengerTrophoblastsConceptsLeukemia inhibitory factorHuman cytotrophoblastsMenstrual cycle-dependent mannerInhibitory factorOncofetal fibronectinEffects of LIFHuman implantationHuman embryonic implantationBeta-HCG mRNAOncofetal fibronectin mRNAMessenger RNA expressionExtravillous phenotypeBeta-hCGMenstrual cycleHuman endometriumNormal implantationEmbryonic implantationProgesterone productionHCG mRNATerm placentaBiochemical markersCultured trophoblastsHuman CGDay 19Steroidogenic activityEndocrinology and paracrinology
Arici A, Tazuke SI, Attar E, Kliman HJ, Olive DL. Endocrinology and paracrinology. Molecular Human Reproduction 1996, 2: 40-45. PMID: 9238656, DOI: 10.1093/molehr/2.1.40.Peer-Reviewed Original ResearchConceptsIL-8 mRNAIL-1 alphaEnzyme-linked immunosorbent assayIL-8 concentrationsPathogenesis of endometriosisInterleukin-8IL-8 proteinPeritoneal fluidMesothelial cellsPg/Human recombinant IL-1 alphaRecombinant IL-1 alphaNeutrophil chemotactic activityMinimal-mild endometriosisPeritoneal mesothelial cellsInterleukin-8 expressionCultured mesothelial cellsPotent angiogenic agentTNF-alpha treatmentModerate-severe endometriosisHuman mesothelial cellsNon-treated cellsControl patientsTime-dependent mannerTNF-alpha
1989
Plasminogen activator inhibitor types 1 and 2 in human trophoblasts. PAI-1 is an immunocytochemical marker of invading trophoblasts.
Feinberg RF, Kao LC, Haimowitz JE, Queenan JT, Wun TC, Strauss JF, Kliman HJ. Plasminogen activator inhibitor types 1 and 2 in human trophoblasts. PAI-1 is an immunocytochemical marker of invading trophoblasts. Laboratory Investigation 1989, 61: 20-6. PMID: 2473276.Peer-Reviewed Original ResearchConceptsPAI-2Plasminogen activator inhibitorSpecific plasminogen activator inhibitorPAI-1Villous syncytiotrophoblastHuman trophoblastsCytoplasmic localizationPlasminogen activatorRegulated productionPAI expressionCytoplasmic stainingCell surface stainingCultured cytotrophoblastsProminent cytoplasmic stainingIntervillous blood flowPlasminogen activator inhibitor type 1Activator inhibitor type 1Inhibitor type 1First trimesterActivatorProteolytic enzymesVascular remodelingVillous cytotrophoblastsBlood flowImmunohistochemical analysis
1988
Biosynthesis and turnover of a 34‐kDa protein growth factor in human cytotrophoblasts
ROY‐CHOUDHURY S, SEN‐MAJUMDAR A, MURTHY U, MISHRA V, KLIMAN H, NESTLER J, STRAUSS J, Manjusri D. Biosynthesis and turnover of a 34‐kDa protein growth factor in human cytotrophoblasts. The FEBS Journal 1988, 172: 777-783. PMID: 3350024, DOI: 10.1111/j.1432-1033.1988.tb13957.x.Peer-Reviewed Original ResearchConceptsProtein growth factorsWestern blot analysisMolecular massPolypeptide molecular massPartial amino acid sequenceAmino acid sequenceBlot analysisGrowth factorMetabolic labeling experimentsPulse-chase experimentsCellular mRNAsVitro translationAcid sequenceReceptor binding specificityBinding specificityIntact cellsLow molecular massBiosynthesisCultured cytotrophoblastsProteinMultinuclear syncytiotrophoblastHuman placentaLabeling experimentsHuman cytotrophoblastsCells
1987
8-Bromo-Adenosine 3′,5′Monophosphate Regulates Expression of Chorionic Gonadotropin and Fibronectin in Human Cytotrophoblasts*
ULLOA-AGUIRRE A, AUGUST A, GOLOS T, KAO L, SAKURAGI N, KLIMAN H, STRAUSS J. 8-Bromo-Adenosine 3′,5′Monophosphate Regulates Expression of Chorionic Gonadotropin and Fibronectin in Human Cytotrophoblasts*. The Journal Of Clinical Endocrinology & Metabolism 1987, 64: 1002-1009. PMID: 2435752, DOI: 10.1210/jcem-64-5-1002.Peer-Reviewed Original Research8-Bromo Cyclic Adenosine MonophosphateChorionic GonadotropinChorionic Gonadotropin, beta Subunit, HumanCulture TechniquesFibronectinsGlycoprotein Hormones, alpha SubunitHumansImmunosorbent TechniquesMethionineMolecular WeightNucleic Acid HybridizationPeptide FragmentsPituitary Hormones, AnteriorRNA, MessengerTrophoblasts