2022
Sex differences in early and term placenta are conserved in adult tissues
Olney K, Plaisier S, Phung T, Silasi M, Perley L, O’Bryan J, Ramirez L, Kliman H, Wilson M. Sex differences in early and term placenta are conserved in adult tissues. Biology Of Sex Differences 2022, 13: 74. PMID: 36550527, PMCID: PMC9773522, DOI: 10.1186/s13293-022-00470-y.Peer-Reviewed Original ResearchConceptsFirst trimester placentaLate first trimesterTerm placentaTrimester placentaFirst trimesterAdult tissuesGene expressionSex differencesLifelong health outcomesSex-differential gene expressionGenetic sexInnate immune responseFull-term placentaSex-linked genesInnate immune genesImmune responsePlacenta samplesHealth outcomesBrain tissuePlacentaGametologous genesDifferent timepointsSex chromosomesImmune genesSex
2008
The fetus, not the mother, elicits maternal immunologic rejection: lessons from discordant dizygotic twin placentas
Yusuf K, Kliman HJ. The fetus, not the mother, elicits maternal immunologic rejection: lessons from discordant dizygotic twin placentas. Journal Of Perinatal Medicine 2008, 36: 291-296. PMID: 18598117, DOI: 10.1515/jpm.2008.054.Peer-Reviewed Original ResearchConceptsChronic villitisTwin placentasT cellsMaternal immunologic rejectionMaternal immune responseNumerous T cellsBirth weight differenceMouse monoclonal antibodyWeight discordancePathologic evidenceDizygotic pregnanciesAutoimmune disordersImmunologic rejectionDichorionic placentasHistologic examinationImmune responseVillitisBacterial infectionsPlacentaMonoclonal antibodiesChorionic villiFetusesMaternal environmentWeight differencesVilli