2008
The Role of piRNAs in Germline Stem Cell Division and Spermatogenesis.
Lin H. The Role of piRNAs in Germline Stem Cell Division and Spermatogenesis. Biology Of Reproduction 2008, 78: 281-281. DOI: 10.1093/biolreprod/78.s1.281a.Peer-Reviewed Original ResearchPIWI-interacting RNAsPIWI subfamily proteinsSubfamily proteinsProtein familyDiverse mechanisms of gene regulationGermline stem cell divisionMechanisms of gene regulationRegulation of mRNA stabilityGermline stem cellsNon-coding small RNAsStem cell self-renewalStem cell divisionPiwi subfamilyGenomic distributionCell self-renewalRepetitive sequencesIntron sequencesGene regulationSmall RNAsSelf-renewalGametogenic eventsCell divisionDiverse organismsPIWIMRNA stability
2006
MIWI associates with translational machinery and PIWI-interacting RNAs (piRNAs) in regulating spermatogenesis
Grivna ST, Pyhtila B, Lin H. MIWI associates with translational machinery and PIWI-interacting RNAs (piRNAs) in regulating spermatogenesis. Proceedings Of The National Academy Of Sciences Of The United States Of America 2006, 103: 13415-13420. PMID: 16938833, PMCID: PMC1569178, DOI: 10.1073/pnas.0605506103.Peer-Reviewed Original ResearchConceptsPIWI-interacting RNAsSmall RNAsTranslational machineryMRNA cap-binding complexArgonaute family proteinsCap-binding complexPIWI family membersPresence of DicerRound spermatidsSubset of miRNAsCytosolic ribonucleoproteinTranslational repressionGene regulationFamily proteinsSubfamily proteinsCytoplasmic proteinsTarget mRNAsMIWIPosttranscriptional levelPolysomal fractionsPolysome fractionsMature spermGene expressionImportant regulatorSpermiogenesis