2008
The Role of piRNAs in Germline Stem Cell Division and Spermatogenesis.
Lin H. The Role of piRNAs in Germline Stem Cell Division and Spermatogenesis. Biology Of Reproduction 2008, 78: 281-281. DOI: 10.1093/biolreprod/78.s1.281a.Peer-Reviewed Original ResearchPIWI-interacting RNAsPIWI subfamily proteinsSubfamily proteinsProtein familyDiverse mechanisms of gene regulationGermline stem cell divisionMechanisms of gene regulationRegulation of mRNA stabilityGermline stem cellsNon-coding small RNAsStem cell self-renewalStem cell divisionPiwi subfamilyGenomic distributionCell self-renewalRepetitive sequencesIntron sequencesGene regulationSmall RNAsSelf-renewalGametogenic eventsCell divisionDiverse organismsPIWIMRNA stabilityCell biology of stem cells: an enigma of asymmetry and self-renewal
Lin H. Cell biology of stem cells: an enigma of asymmetry and self-renewal. Journal Of Cell Biology 2008, 180: 257-260. PMID: 18227277, PMCID: PMC2213586, DOI: 10.1083/jcb.200712159.Peer-Reviewed Original ResearchConceptsCell biologyStem cellsIntrinsic cell polarityDrosophila melanogaster neuroblastsGermline stem cellsStem cell divisionStem cell systemCell cycle regulatorsSkin stem cellsNiche signalingCell polarityAsymmetric divisionDaughter cellsCell divisionCycle regulatorsStem cell researchBiologyCell researchCell systemCellsCrucial roleTherapeutic applicationsDivisionDiverse typesCentrosomes
2003
Screens for piwi Suppressors in Drosophila Identify Dosage-Dependent Regulators of Germline Stem Cell Division
Smulders-Srinivasan TK, Lin H. Screens for piwi Suppressors in Drosophila Identify Dosage-Dependent Regulators of Germline Stem Cell Division. Genetics 2003, 165: 1971-1991. PMID: 14704180, PMCID: PMC1462913, DOI: 10.1093/genetics/165.4.1971.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAnimals, Genetically ModifiedArgonaute ProteinsCell DivisionChromosomesDrosophilaDrosophila ProteinsFemaleGene DosageGene Expression Regulation, DevelopmentalGenes, LethalGerm CellsInfertility, MaleMaleProteinsRNA-Induced Silencing ComplexStem CellsSuppression, GeneticTranscription, GeneticZygoteConceptsStem cell divisionGermline stem cell divisionGenes/sequencesCell divisionFemale-specific lethalityDosage-dependent regulatorGermline stem cellsStem cell maintenanceDrosophila third chromosomeFamily of genesDosage-sensitive mannerPiwi mutantsZygotic functionMutant backgroundPiwi genesThird chromosomeMale germlineMale sterilitySuppressor mutationsSuch genesCell maintenanceGenetic regulationPlant kingdomTranscription factorsTranscriptional level