2021
AMH Highly Correlates With Cumulative Live Birth Rate in Women with Diminished Ovarian Reserve Independent of Age*
Tal R, Seifer DB, Tal R, Granger E, Wantman E, Tal O. AMH Highly Correlates With Cumulative Live Birth Rate in Women with Diminished Ovarian Reserve Independent of Age*. The Journal Of Clinical Endocrinology & Metabolism 2021, 106: 2754-2766. PMID: 33729496, DOI: 10.1210/clinem/dgab168.Peer-Reviewed Original ResearchConceptsCumulative live birth rateDiminished ovarian reserveLive birth rateSerum AMHLive birthsAge strataRetrieval cycleAntimüllerian hormone levelsReproductive technology cyclesCumulative live birthMain outcome measuresMultiple logistic regressionNumber of oocytesBirth rateRegression analysisPreimplantation genetic testingAddition of AMHPercentage of cyclesOvarian reserveIndependent predictorsOvarian responseHormone levelsRetrospective analysisOutcome measuresEmbryo transferEthnicity/Race and Age-Specific Variations of Serum AMH in Women—A Review
Kotlyar AM, Seifer DB. Ethnicity/Race and Age-Specific Variations of Serum AMH in Women—A Review. Frontiers In Endocrinology 2021, 11: 593216. PMID: 33633682, PMCID: PMC7900163, DOI: 10.3389/fendo.2020.593216.Peer-Reviewed Original Research
2018
Temporal Differences in Utilization of Intracytoplasmic Sperm Injection Among U.S. Regions
Zagadailov P, Hsu A, Stern JE, Seifer DB. Temporal Differences in Utilization of Intracytoplasmic Sperm Injection Among U.S. Regions. Obstetrics And Gynecology 2018, 132: 310-320. PMID: 29995722, DOI: 10.1097/aog.0000000000002730.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge FactorsCohort StudiesFemaleFertilization in VitroHumansInfertility, FemaleInfertility, MaleLive BirthMalePregnancyPregnancy RateRetrospective StudiesSperm Injections, IntracytoplasmicTreatment OutcomeUnited StatesUnited States Dept. of Health and Human ServicesYoung AdultConceptsLive birth rateUse of ICSIICSI rateICSI utilizationBirth rateRetrospective cohort studyMale factor infertilityHuman Services (HHS) regionsIntracytoplasmic sperm injectionYears of agePreimplantation genetic testingMale factor diagnosisDepartment of HealthNondonor cyclesCohort studyFertilization cyclesFactor infertilityMale factorSperm injectionMedical indicationsMagnitude of increaseClinicGenetic testingDisease controlICSI
2014
Putting ‘family’ back in family planning
Seifer DB, Minkoff H, Merhi Z. Putting ‘family’ back in family planning. Human Reproduction 2014, 30: 16-19. PMID: 25406182, DOI: 10.1093/humrep/deu304.Peer-Reviewed Original ResearchMeSH KeywordsAdultAge FactorsFamily Planning ServicesFemaleFertilityHumansInfertilityMaleMaternal Age
2012
Anti-Müllerian hormone as an independent predictor of twin versus singleton pregnancy in fresh cycles
Tal R, Seifer DB, Khanimov M, Schwartz E, Grazi RV, Malter HE. Anti-Müllerian hormone as an independent predictor of twin versus singleton pregnancy in fresh cycles. Reproductive BioMedicine Online 2012, 26: 360-367. PMID: 23419793, DOI: 10.1016/j.rbmo.2012.12.002.Peer-Reviewed Original ResearchConceptsAnti-Müllerian hormoneSerum AMH concentrationsFresh non-donor cyclesSerum anti-Müllerian hormoneNon-donor cyclesTwin pregnanciesAMH concentrationsSingleton pregnanciesIndependent predictorsIncidence of twinsFresh cyclesMultiple pregnanciesFertility clinicsPossible predictorsEgg reserveQuantitative ovarian responseLive birth rateChance of pregnancyROC curve analysisSignificant predictive abilityMultiple gestationsOvarian responseTwin gestationsRetrospective studyPregnancy rateHigh frequency of discordance between antimüllerian hormone and follicle-stimulating hormone levels in serum from estradiol-confirmed days 2 to 4 of the menstrual cycle from 5,354 women in U.S. fertility centers
Leader B, Hegde A, Baca Q, Stone K, Lannon B, Seifer DB, Broekmans F, Baker VL. High frequency of discordance between antimüllerian hormone and follicle-stimulating hormone levels in serum from estradiol-confirmed days 2 to 4 of the menstrual cycle from 5,354 women in U.S. fertility centers. Fertility And Sterility 2012, 98: 1037-1042. PMID: 22771028, DOI: 10.1016/j.fertnstert.2012.06.006.Peer-Reviewed Original ResearchMeSH KeywordsAdultAge FactorsAnti-Mullerian HormoneChemistry, ClinicalEstradiolFemaleFertilityFollicle Stimulating Hormone, HumanHumansMenstrual CycleMiddle AgedOocytesOvulation InductionPredictive Value of TestsPrognosisReference StandardsReproductive MedicineRetrospective StudiesUnited StatesYoung AdultConceptsYears of ageFSH valuesSerum AMHAntimüllerian hormoneAMH valuesFertility centerCut pointsDay 2Clinical discordanceMenstrual cycle day 2Follicle-stimulating hormone levelsCycle day 2Reference laboratoryFollicle-stimulating hormoneLarger patient populationSingle reference laboratoryFrequency of discordanceAge-dependent fashionClinical cut pointsSame serum samplesOvarian stimulationPatient populationAMH testingMenstrual cycleHormone levelsCirculating vitamin D correlates with serum antimüllerian hormone levels in late-reproductive-aged women: Women's Interagency HIV Study
Merhi ZO, Seifer DB, Weedon J, Adeyemi O, Holman S, Anastos K, Golub ET, Young M, Karim R, Greenblatt R, Minkoff H. Circulating vitamin D correlates with serum antimüllerian hormone levels in late-reproductive-aged women: Women's Interagency HIV Study. Fertility And Sterility 2012, 98: 228-234. PMID: 22494925, PMCID: PMC3389125, DOI: 10.1016/j.fertnstert.2012.03.029.Peer-Reviewed Original ResearchConceptsWomen's Interagency HIV StudySerum antimüllerian hormoneAntimüllerian hormoneInsulin levelsHIV StudyAged womenGroup 2Group 1Group 3Serum antimüllerian hormone levelsVitamin D correlateAntimüllerian hormone levelsGlomerular filtration rateLow ovarian reserveRegular menstrual cyclesBody mass indexCross-sectional studyIllicit drug usePremenopausal womenCreatinine levelsOvarian reserveHIV statusMass indexD levelsFiltration rate
2010
Age-specific serum anti-Müllerian hormone values for 17,120 women presenting to fertility centers within the United States
Seifer DB, Baker VL, Leader B. Age-specific serum anti-Müllerian hormone values for 17,120 women presenting to fertility centers within the United States. Fertility And Sterility 2010, 95: 747-750. PMID: 21074758, DOI: 10.1016/j.fertnstert.2010.10.011.Peer-Reviewed Original ResearchConceptsAnti-Müllerian hormone valuesAMH valuesHormone valuesAge 35Mean AMH valueSerum AMH valuesAverage yearly decreaseYears of ageU.S. fertility clinicsSpecific medianAMH levelsClinical reference laboratoryRetrospective studyFertility centerReproductive ageMAIN OUTCOMEAge 40Rate of declineFertility clinicsReference laboratoryWomenAgeReproductive optionsYearly decreaseSD values
2007
Relationship of bariatric surgery to Müllerian-inhibiting substance levels
Merhi ZO, Minkoff H, Feldman J, Macura J, Rodriguez C, Seifer DB. Relationship of bariatric surgery to Müllerian-inhibiting substance levels. Fertility And Sterility 2007, 90: 221-224. PMID: 17727846, DOI: 10.1016/j.fertnstert.2007.05.073.Peer-Reviewed Original Research
2003
In vitro fertilization in the older patient.
Derman SG, Seifer DB. In vitro fertilization in the older patient. Current Women'S Health Reports 2003, 3: 375-83. PMID: 12959695.Peer-Reviewed Original ResearchConceptsOlder patientsClomiphene citrate challenge testBasal follicle-stimulating hormoneAntral follicle countDiminished ovarian reserveLower oocyte yieldFollicle-stimulating hormoneHigher miscarriage rateMüllerian-inhibiting substanceHigher cancellation rateIVF success ratesLower pregnancy ratesFlare protocolInhibin BIVF patientsMiscarriage rateOvarian reserveOvarian volumeFollicle countGnRH antagonistOocyte yieldEstradiol levelsPregnancy rateAgonist doseStimulation protocol
1999
Women with declining ovarian reserve may demonstrate a decrease in day 3 serum inhibin B before a rise in day 3 follicle-stimulating hormone
Seifer D, Scott R, Bergh P, Abrogast L, Friedman C, Mack C, Danforth D. Women with declining ovarian reserve may demonstrate a decrease in day 3 serum inhibin B before a rise in day 3 follicle-stimulating hormone. Fertility And Sterility 1999, 72: 63-65. PMID: 10428149, DOI: 10.1016/s0015-0282(99)00193-4.Peer-Reviewed Original ResearchConceptsSerum inhibin B levelsInhibin B levelsDay 3 FSH levelsCycle cancellation rateClinical pregnancy rateSerum inhibin BOvarian reserveFSH levelsB levelsInhibin BPregnancy rateCancellation rateDay 3 follicle-stimulating hormoneDay 3 serum FSH levelsHigher cycle cancellation rateTertiary-care fertility centreNumber of ampulesSerum FSH levelsSerum FSH concentrationsFollicle-stimulating hormoneCase-control studyNumber of oocytesOvarian responsivenessFSH concentrationsGonadotropin requirements
1995
Laparoscopic-assisted tubal anastomosis
Frishman G, Seifer D. Laparoscopic-assisted tubal anastomosis. Journal Of Minimally Invasive Gynecology 1995, 2: 411-415. PMID: 9050594, DOI: 10.1016/s1074-3804(05)80062-3.Peer-Reviewed Original ResearchConceptsTubal anastomosisHospital stayPregnancy rateLower body mass indexPostoperative pregnancy rateClinical pregnancy rateTertiary care settingBody mass indexLength of procedureLong-term resultsLaparoscopic approachMass indexPatent tubesSame surgeonTubal ligationTubal segmentsCare settingsLaparotomyLarger studyPatientsAnastomosisLatter groupSimilar time periodWomenLaparoscopic