2023
Dysregulated expression of GATA2 and GATA6 transcription factors in adenomyosis: implications for impaired endometrial receptivity
Pavlovic Z, Hsin-Yu Pai A, Hsiao T, Yen C, Alhasan H, Ozmen A, New E, Guo X, Imudia A, Guzeloglu-Kayisli O, Lockwood C, Kayisli U. Dysregulated expression of GATA2 and GATA6 transcription factors in adenomyosis: implications for impaired endometrial receptivity. F&S Science 2023, 5: 92-103. PMID: 37972693, DOI: 10.1016/j.xfss.2023.11.003.Peer-Reviewed Original ResearchHuman endometrial stromal cellsInsulin-like growth factor-binding protein-1Estrogen receptor 1Leukemia inhibitory factorEndometrial stromal cellsProgesterone receptorControl patientsEndometrial sectionsGATA2 overexpressionH-scoreMRNA levelsInhibitory factorStromal cellsGrowth factor-binding protein-1Effect of adenomyosisReproductive-age patientsImpaired endometrial receptivityPotential therapeutic targetYears of ageMessenger RNA levelsEndometrial implantationWestern blot analysisAdenomyosis patientsLIF levelsAge patients
2000
Progestin-Epidermal Growth Factor Regulation of Tissue Factor Expression during Decidualization of Human Endometrial Stromal Cells
Lockwood C. Progestin-Epidermal Growth Factor Regulation of Tissue Factor Expression during Decidualization of Human Endometrial Stromal Cells. The Journal Of Clinical Endocrinology & Metabolism 2000, 85: 297-301. DOI: 10.1210/jc.85.1.297.Peer-Reviewed Original Research
1996
Expression of 11 beta-hydroxysteroid dehydrogenase during decidualization of human endometrial stromal cells
Arcuri F, Monder C, Lockwood C, Schatz F. Expression of 11 beta-hydroxysteroid dehydrogenase during decidualization of human endometrial stromal cells. Endocrinology 1996, 137: 595-600. DOI: 10.1210/en.137.2.595.Peer-Reviewed Original ResearchBeta-HSD expressionBeta-HSD activitySensitivity of mRNA detectionLow-abundance messageHSD activityType I mRNABeta-hydroxysteroid dehydrogenaseI mRNANAD(+)-dependentNADP(+)-dependentSteady state levelsDecidualization of human endometrial stromal cellsRegulates extracellular matrix turnoverNorthern analysisAbundant messageCultured stromal cellsHuman endometrial stromal cellsMedroxyprogesterone acetateBeta-hydroxysteroidEndometrial stromal cellsStromal cellsEnzyme activityTime course measurementsEarly eventExtracellular matrix turnover