2015
An update on the current pharmacotherapy for endometrial cancer
de Haydu C, Black JD, Schwab CL, English DP, Santin AD. An update on the current pharmacotherapy for endometrial cancer. Expert Opinion On Pharmacotherapy 2015, 17: 489-499. PMID: 26629895, DOI: 10.1517/14656566.2016.1127351.Peer-Reviewed Original ResearchMeSH KeywordsAntineoplastic AgentsAntineoplastic Agents, HormonalChemotherapy, AdjuvantEndometrial NeoplasmsFemaleHumansMolecular Targeted TherapyConceptsEndometrial cancerMainstay of treatmentCommon gynecologic malignancyCurrent conventional therapiesGynecologic malignanciesCurrent pharmacotherapyAvailable pharmacotherapiesConventional therapyCurrent therapiesEndometrial tumorsTargeted therapyImmunohistochemical characterizationRadiation therapyClinical careAggressive formNew therapiesPreclinical settingTherapyTherapeutic agentsCancerPharmacotherapyTumorsAvailable literatureHistoric treatmentTreatment
2007
Metastatic Uterine Leiomyosarcoma Regression Using an Aromatase Inhibitor
Hardman MP, Roman JJ, Burnett AF, Santin AD. Metastatic Uterine Leiomyosarcoma Regression Using an Aromatase Inhibitor. Obstetrics And Gynecology 2007, 110: 518-520. PMID: 17666649, DOI: 10.1097/01.aog.0000267533.56546.c2.Peer-Reviewed Original ResearchConceptsUterine leiomyosarcomaAromatase inhibitorsTotal abdominal hysterectomyUterine leiomyosarcoma metastaticEstrogen receptor positivityPrimary uterine leiomyosarcomaMetastatic tumor nodulesAdjuvant platinumAnastrozole dailyLeiomyosarcoma metastaticAbdominal hysterectomyObjective responseReceptor positivityTumor depositsChemotherapeutic optionsDoxorubicin chemotherapySerial imagingTumor regressionTumor nodulesLeiomyosarcomaLungInhibitorsHysterectomyNulligravidaMetastatic
2004
Current treatment options for endometrial cancer
Santin AD, Bellone S, O’Brien T, Pecorelli S, Cannon MJ, Roman JJ. Current treatment options for endometrial cancer. Expert Review Of Anticancer Therapy 2004, 4: 679-689. PMID: 15270671, DOI: 10.1586/14737140.4.4.679.Peer-Reviewed Original ResearchMeSH KeywordsAntibodies, MonoclonalAntibodies, Monoclonal, HumanizedAntineoplastic Agents, HormonalAntineoplastic Combined Chemotherapy ProtocolsCarboplatinCell DifferentiationCisplatinDoxorubicinEndometrial NeoplasmsFemaleHumansHysterectomyNeoplasm InvasivenessNeoplasm Recurrence, LocalOvariectomyPaclitaxelPrognosisRadiotherapy, AdjuvantReceptor, ErbB-2Risk FactorsSurvival AnalysisTrastuzumabConceptsEndometrial cancerMyometrial invasionStage I endometrial cancer patientsLow-toxicity regimenEndometrial cancer patientsLymph node dissectionRecurrent endometrial cancerTotal abdominal hysterectomyClear cell histologyCornerstone of treatmentPostoperative radiation therapyImportant prognostic factorCurrent treatment optionsCombination of cisplatinFemale genital tractAttractive therapeutic strategyMajority of casesType II receptorExtrapelvic recurrenceAbdominal hysterectomyNode dissectionPelvic radiotherapyPelvic recurrenceSystemic chemotherapyVaginal bleeding