2017
Moving forward with actionable therapeutic targets and opportunities in endometrial cancer: NCI clinical trials planning meeting report on identifying key genes and molecular pathways for targeted endometrial cancer trials
MacKay HJ, Levine DA, Bae-Jump VL, Bell DW, McAlpine JN, Santin A, Fleming GF, Mutch DG, Nephew KP, Wentzensen N, Goodfellow PJ, Dorigo O, Nijman HW, Broaddus R, Kohn EC. Moving forward with actionable therapeutic targets and opportunities in endometrial cancer: NCI clinical trials planning meeting report on identifying key genes and molecular pathways for targeted endometrial cancer trials. Oncotarget 2017, 5: 84579-84594. PMID: 29137450, PMCID: PMC5663622, DOI: 10.18632/oncotarget.19961.Peer-Reviewed Original ResearchEndometrial cancerClinical trialsEndometrial cancer managementEndometrial cancer trialsFuture clinical trialsActionable therapeutic targetsNCI clinical trialsNational Cancer InstituteHistologic stratificationCancer trialsCancer managementCancer InstituteMortality rateTherapeutic targetTherapeutic directionsNew drugsCancerMolecular pathwaysTrialsMeeting reportSteering CommitteeActionable opportunitiesGroup of expertsKey genesIncidence
2012
EGFR/HER-targeted therapeutics in ovarian cancer
Wilken JA, Badri T, Cross S, Raji R, Santin AD, Schwartz P, Branscum AJ, Baron AT, Sakhitab AI, Maihle NJ. EGFR/HER-targeted therapeutics in ovarian cancer. Future Medicinal Chemistry 2012, 4: 447-469. PMID: 22416774, PMCID: PMC4620931, DOI: 10.4155/fmc.12.11.Peer-Reviewed Original ResearchConceptsEpithelial ovarian cancerOvarian cancerHuman epidermal growth factor receptor (HER) familyEpidermal growth factor receptor familyGrowth factor receptor familyTreatment modalitiesFactor receptor familyClinical developmentDiverse malignanciesEGFR/Clinical settingUS FDACancerNew drugsReceptor familyPatientsMalignancyTherapeuticsTreatmentTyrosine kinaseSurvivalSame periodCarcinomaMajor roleEtiology