2016
Post-Translational Modifications in sperm Proteome: The Chemistry of Proteome diversifications in the Pathophysiology of male factor infertility
Samanta L, Swain N, Ayaz A, Venugopal V, Agarwal A. Post-Translational Modifications in sperm Proteome: The Chemistry of Proteome diversifications in the Pathophysiology of male factor infertility. Biochimica Et Biophysica Acta 2016, 1860: 1450-1465. PMID: 27062907, DOI: 10.1016/j.bbagen.2016.04.001.Peer-Reviewed Original ResearchConceptsPost-translational modificationsSperm proteinsSperm functionOccurrence of post-translational modificationsExpressed protein complementHuman sperm proteinsProtein synthesis machineryAnalysis of post-translational modificationsComplex interaction networksProteome diversificationSperm proteomeFemale reproductive tractHuman spermatozoaProtein complementStructure-function relationshipsSynthesis machineryInteraction networkProtein stabilityMale infertilitySpermMale factor infertilitySpermatozoaProtein profilesDifferential occurrenceFertility potential
2014
Effects of sphingosylphosphorylcholine against oxidative stress and acute lung ınjury ınduced by pulmonary contusion in rats
Aksu B, Ayvaz S, Aksu F, Karaca T, Cemek M, Ayaz A, Demirtaş S. Effects of sphingosylphosphorylcholine against oxidative stress and acute lung ınjury ınduced by pulmonary contusion in rats. Journal Of Pediatric Surgery 2014, 50: 591-597. PMID: 25840069, DOI: 10.1016/j.jpedsurg.2014.06.007.Peer-Reviewed Original ResearchConceptsAcute lung injuryPulmonary contusionLung injuryInducible nitric oxide synthaseLung tissueSeverity of lung injurySphingosylphosphorylcholine treatmentAdministered 3 daysNitric oxideAttenuated lung damageOxidative stressNitric oxide synthaseEffects of sphingosylphosphorylcholineGlutathione peroxidaseDepletion of superoxide dismutaseSuperoxide dismutaseLung malondialdehydeHistopathological findingsPositive cellsLung damageImmunohistochemical changesInflammatory processNeutrophil activationOxide synthaseApoptotic cells
2013
Desferrioxamine effectively attenuates testicular tissue at the end of 3 h of ischemia but not in an equal period of reperfusion
Ayvaz S, Inan M, Aksu B, Karaca T, Cemek M, Ayaz A, Basaran U, Pul M. Desferrioxamine effectively attenuates testicular tissue at the end of 3 h of ischemia but not in an equal period of reperfusion. Journal Of Pediatric Urology 2013, 10: 550-558. PMID: 24440694, DOI: 10.1016/j.jpurol.2013.11.019.Peer-Reviewed Original ResearchConceptsDesferrioxamine groupT/D groupTesticular tissueControl groupContralateral testis damageSeminiferous tubule diameterT groupPeriod of reperfusionPreventing ischemic damageContralateral testisTestis torsionBiopsy scorePlasma catalase activityRight testisTestis damageTissue glutathione levelsEffect of desferrioxamineTubule diameterDetorsionIschemic damageHistopathological methodsPlasma glutathione peroxidase activityBlood samplesGlutathione peroxidase activityTorsion/detorsion
2012
Serum and Liver Tissue Bio-Element Levels, and Antioxidant Enzyme Activities in Carbon Tetrachloride-Induced Hepatotoxicity: Protective Effects of Royal Jelly
Cemek M, Yılmaz F, Büyükokuroğlu M, Büyükben A, Aymelek F, Ayaz A. Serum and Liver Tissue Bio-Element Levels, and Antioxidant Enzyme Activities in Carbon Tetrachloride-Induced Hepatotoxicity: Protective Effects of Royal Jelly. Journal Of Medicinal Food 2012, 15: 747-752. PMID: 22510102, DOI: 10.1089/jmf.2012.0010.Peer-Reviewed Original Research