Proteomic analysis of sperm proteins in infertile men with high levels of reactive oxygen species
Ayaz A, Agarwal A, Sharma R, Kothandaraman N, Cakar Z, Sikka S. Proteomic analysis of sperm proteins in infertile men with high levels of reactive oxygen species. Andrologia 2018, 50: e13015. PMID: 29656391, DOI: 10.1111/and.13015.Peer-Reviewed Original ResearchMeSH KeywordsAdultAmyloid beta-Protein PrecursorAntigens, NeoplasmF-Box ProteinsHSP70 Heat-Shock ProteinsHumansInfertility, MaleMaleMAP Kinase Kinase Kinase 3Nerve Tissue ProteinsNitric Oxide Synthase Type IIPeptidyl-Dipeptidase AProteomicsReactive Oxygen SpeciesRibosomal ProteinsSmall Ubiquitin-Related Modifier ProteinsSpermatozoaTestisUbiquitinsConceptsReactive oxygen speciesSperm proteinsMale infertilityAngiotensin-converting enzymePost-acrosomal regionPoor sperm qualityLevels of reactive oxygen speciesSperm qualityTesticular environmentInfertile menHeat shock proteinsProteomic analysisHSPA2SpermatozoaExpression profilesOxidative stressRPS27aProteinOxygen speciesMAP3K3Western blottingNeck areaRisk factorsUBL4ASpermChapter 21 Impact of Environmental Factors on the Genomics and Proteomics Landscapes of Male Infertility
Ayaz A, Kothandaraman N, Henkel R, Sikka S. Chapter 21 Impact of Environmental Factors on the Genomics and Proteomics Landscapes of Male Infertility. 2018, 335-353. DOI: 10.1016/b978-0-12-801299-4.00021-9.Peer-Reviewed Original ResearchGenetic materialMale infertilityAnalysis of posttranslational modificationsSperm genetic materialSperm epigenomeFunctional genomicsPosttranslational modificationsEnvironmental factorsMicroarray technologyProteomic landscapeGlobal proteinGenetic changesReproductive cellsCritical proteinsDNA structureBioinformatics applicationsProteomic techniquesAdverse effects of environmentGenomeProteinProteomicsDNAImpact of environmental factorsHigh-resolution assessmentInfertile couples