Study: Alzheimer's Drug Shows Modest Success Slowing Declines in Memory, Thinking
Christopher Van Dyck, MD, professor of psychiatry and director of the Alzheimer's Disease Research Unit, spoke about an experimental drug for Alzheimer's disease patients at the Clinical Trials on Alzheimer's Disease meeting in San Francisco in November.Source: NPR
A VA Biobank is the Largest Source of Genetic Data on Black Americans
Joel Gelernter, MD, Foundations Fund Professor of Psychiatry and Professor of Genetics and of Neuroscience, spoke to The Washington Post about the Million Veteran Program (MVP), a federally funded genetic biobank and the single-largest source of genetic data on Black Americans.Source: The Washington Post
Yale Study Revises Understanding of How the Brain Processes and Responds to Rewards
A new Yale study of neuron activity in the brain has revised scientists’ understanding of how the brain processes and responds to rewards. Marina Picciotto, PhD, Charles B. G. Murphy Professor of Psychiatry and Professor in the Child Study Center, of Neuroscience and of Pharmacology, is the study’s senior author.
Dr. John Krystal — All Things Ketamine
John H. Krystal, MD, Robert L. McNeil, Jr. Professor of Translational Research and Professor of Psychiatry, of Neuroscience, and of Psychology and Chair of the Yale Department of Psychiatry, recently discussed his groundbreaking research into the drug ketamine on the Tim Ferriss Show.Source: The Tim Ferriss Show
Orientation selectivity enhances context generalization and generative predictive coding in the hippocampus
The lab of George Dragoi, MD, PhD, Associate Professor of Psychiatry and of Neuroscience, recently published a new study in Neuron that found orientation selectivity enhances context generalization and generative predictive coding in the hippocampus.Source: Neuron
Stress and Resilience Town Halls
Beginning Friday, March 20, the Department of Psychiatry will offer virtual “Stress and Resilience town halls” over Zoom that are open to all faculty, residents, students, and staff at Yale School of Medicine and Yale New Haven Health. Virtual meetings will take place twice daily and run for up to an hour. Individuals can attend as frequently as they like.
Yale Scientists Awarded $8.4M Grant to Develop Treatments for Women With Problem Drinking
Yale Department of Psychiatry scientists have been awarded a five-year, $8.4 million federal grant to establish a new research center at Yale that will develop treatments to help women with problem drinking.
Yale Genomics Study: Helping Researchers Better Understand the Opioid Epidemic
A human genomics study led by two Yale Department of Psychiatry researchers identified specific genetic regions that link opioid exposure and dependence to neuropsychiatric traits like risk-taking behaviors, alcohol abuse, and depression.
Yale Study: Ketamine Disinhibits Dendrites and Enhances Calcium Signals in Prefrontal Dendritic Spines
In a study published in Nature Communications, Alex Kwan, PhD, Associate Professor of Psychiatry, and his research team found that within an hour after a mouse received ketamine, there is a substantial increase in the amount of calcium that goes into the dendritic spines for neurons in the prefrontal cortex.
Yale Researchers Find Genetic Clues to Troubling PTSD Symptom
Symptoms of post-traumatic stress disorder (PTSD) overlap with several other psychiatric disorders, but one specific symptom — repeated disturbing memories and flashbacks about a specific event — is a defining characteristic of debilitating PTSD.
The Secret of Autobiographical Memory is in Assembly of Cells
Of all forms of memory, episodic memory is the most intimate. We recall the sequences of events that happen to us — a marriage, a visit to a foreign country, a personal achievement — in great autobiographical detail. But scientists have disagreed about the most important elements the brain uses to encode these episodes and consolidate them during sleep. A group of Yale scientists, however, reports that it is the size and shape of neuronal assemblies — not the strength of signals processed by neurons or the order in which neurons fire — that are the most crucial elements in our ability to record past events.
How the Brain Helps Us Make Good Decisions — and Bad Ones
A prevailing theory in neuroscience holds that people make decisions based on integrated global calculations that occur within the frontal cortex of the brain. However, Yale researchers have found that three distinct circuits connecting to different brain regions are involved in making good decisions, bad ones, and determining which of those past choices to store in memory, they report June 25 in the journal Neuron.
Scientists Restore Some Functions in a Pig’s Brain Hours After Death
Circulation and cellular activity were restored in a pig’s brain four hours after its death, a finding that challenges long-held assumptions about the timing and irreversible nature of the cessation of some brain functions after death, Yale scientists report in the journal Nature.
YJBM 2018-2019 Colloquium Series: "Top-down Regulation of Attention by Prefrontal Cortex: Dysfunction in Attention Disorders" on March 25
Dr. Amy Arnsten will speak from 2:30-3:30 p.m. on March 25th in BCMM 206/208 (295 Congress St.), delivering a lecture titled: "Top-down Regulation of Attention by Prefrontal Cortex: Dysfunction in Attention Disorders." Light refreshments will be provided.