2016
Respiration Gates Sensory Input Responses in the Mitral Cell Layer of the Olfactory Bulb
Short SM, Morse TM, McTavish TS, Shepherd GM, Verhagen JV. Respiration Gates Sensory Input Responses in the Mitral Cell Layer of the Olfactory Bulb. PLOS ONE 2016, 11: e0168356. PMID: 28005923, PMCID: PMC5179112, DOI: 10.1371/journal.pone.0168356.Peer-Reviewed Original ResearchConceptsMitral cell layerOlfactory bulbCell layerPeriod of inhalationOdor processingGranule cell layerGranule cell inhibitionSingle-unit recordingsMitral/Inhibitory responsesUnit recordingsAction potentialsMTC responsesRespiratory cycleCell inhibitionSensory processingDiscrete sensory inputsInhibitory mechanismSensory responsesSensory inputInhalationMechanism of inhibitionInhibitory activityInhibitionSensory
2010
Abnormal Excitability of Oblique Dendrites Implicated in Early Alzheimer's: A Computational Study
Morse TM, Carnevale NT, Mutalik PG, Migliore M, Shepherd GM. Abnormal Excitability of Oblique Dendrites Implicated in Early Alzheimer's: A Computational Study. Frontiers In Neural Circuits 2010, 4: 16. PMID: 20725509, PMCID: PMC2901152, DOI: 10.3389/fncir.2010.00016.Peer-Reviewed Original ResearchOblique dendritesCognitive functionEarly Alzheimer'sPyramidal cell dendritesAmyloid beta proteinNeural basisAbnormal excitabilityPyramidal dendritesProximal dendritesDistal dendritesCell dendritesApical trunkAnimal modelsElectrophysiological studiesAction potentialsOblique branchHyperexcitabilityExcessive calcium concentrationsCalcium concentrationEarly exposureIntegrative propertiesBeta proteinEarly declineRecording sitesAlzheimer's