2001
Programmed Cell Death of Developing Mammalian Neurons after Genetic Deletion of Caspases
Oppenheim R, Flavell R, Vinsant S, Prevette D, Kuan C, Rakic P. Programmed Cell Death of Developing Mammalian Neurons after Genetic Deletion of Caspases. Journal Of Neuroscience 2001, 21: 4752-4760. PMID: 11425902, PMCID: PMC6762357, DOI: 10.1523/jneurosci.21-13-04752.2001.Peer-Reviewed Original ResearchConceptsCell deathGenetic deletionExtensive cytoplasmic vacuolizationPro-apoptotic proteasesCaspase familySpecific caspasesChromatin condensationNonapoptotic pathwaysPostmitotic neuronsCaspase-9Mammalian neuronsCell typesDeath processSpecific perturbationsCaspase-3Altered morphologyCaspasesNuclear changesKey membersDeletionUTP nickCytoplasmic vacuolizationElectron microscopic levelTerminal deoxynucleotidyl transferase-mediated biotinylated UTP nickNeuronal populations
1999
Continuation of neurogenesis in the hippocampus of the adult macaque monkey
Kornack D, Rakic P. Continuation of neurogenesis in the hippocampus of the adult macaque monkey. Proceedings Of The National Academy Of Sciences Of The United States Of America 1999, 96: 5768-5773. PMID: 10318959, PMCID: PMC21935, DOI: 10.1073/pnas.96.10.5768.Peer-Reviewed Original ResearchConceptsAdult macaque monkeysDentate gyrusMacaque monkeysAdult primate hippocampusAdult rodent dentate gyrusImmunohistochemical double labelingHippocampal dentate gyrusRodent dentate gyrusDiscreet brain regionsMultipotent neural stem cellsNeural stem cellsAdult neurogenesisAdult brainPrimate hippocampusAnimal modelsBrain regionsDouble labelingNeurogenesisSpecific markersHippocampusGyrusStem cellsCell typesMonkeysHumans
1994
Neurons and astroglia express distinct subsets of Na,K-ATPase α and β subunits
Cameron R, Klein L, Shyjan A, Rakic P, Levenson R. Neurons and astroglia express distinct subsets of Na,K-ATPase α and β subunits. Brain Research 1994, 21: 333-343. PMID: 8170354, DOI: 10.1016/0169-328x(94)90264-x.Peer-Reviewed Original ResearchConceptsCentral nervous systemHippocampal neuronsNervous systemK-ATPase isoenzymesPanel of alphaMammalian central nervous systemType-1 astrocytesCerebellar granule neuronsAlpha 3 subunitCell typesRat cerebellar granuleAlpha 1 isoformCortical astrocytesBeta 1 subunitGranule neuronsMonkey brainK-ATPase alphaAlpha-subunit isoformsImmunofluorescent staining patternsCerebellar granuleNeuronsStaining patternAlpha 2Distinct subsetsAlpha 3
1982
Ontogeny State of the Art Report
Strichartz G, Aguayo A, Cowan W, Distel H, Lim L, McKhann G, Mugnaini E, Rakic P, Rickmann M, Spitzer N, Webster H. Ontogeny State of the Art Report. Dahlem Workshop Report 1982, 93-114. DOI: 10.1007/978-3-642-68466-1_9.Peer-Reviewed Original Research
1981
Coexistence of neuronal and glial precursor cells in the cerebral ventricular zone of the fetal monkey: an ultrastructural immunoperoxidase analysis
Levitt P, Cooper M, Rakic P. Coexistence of neuronal and glial precursor cells in the cerebral ventricular zone of the fetal monkey: an ultrastructural immunoperoxidase analysis. Journal Of Neuroscience 1981, 1: 27-39. PMID: 7050307, PMCID: PMC6564162, DOI: 10.1523/jneurosci.01-01-00027.1981.Peer-Reviewed Original ResearchConceptsGlial fibrillary acid proteinLast cell divisionCell divisionRadial glial cellsNeuronal cell lineAcid proteinCerebral ventricular zoneEmbryonic day 80Proliferative zoneGlial precursor cellsMitotic cycleCell typesPeak of neurogenesisPrecursor cellsCell linesVentricular zoneElectron microscopic levelFetal monkeysProliferative cellsGlial cellsSubventricular zoneOccipital lobePhenotypic expressionCytological compositionDistinct classes