Two studies using brain organoids reveal cell-type-specific changes during the early stages of human forebrain neuronal development in autism
SFARI Investigators Flora Vaccarino at Yale University and Alexej Abyzov at Mayo Clinic used brain organoids to investigate neurobiological mechanisms linking brain size with idiopathic autism (autism without a known cause) (Jourdon et al., Nat. Neurosci., 2023).
- November 01, 2023
Getting it “right” with medical AI
- October 12, 2023Source: Charles Choi, Spectrum News
Opposite paths in fetal brain development may explain two major subtypes of autism, a new study finds.
- September 07, 2023Source: Connecticut Public Radio
Researchers at the Yale School of Medicine’s Child Study Center have discovered at least two different types of autism. The findings, published in the journal Nature Neuroscience, suggest a need for more than just one drug to treat symptoms.
- August 16, 2023Source: Science
Every person is actually a mosaic of genomes, varying across the body and often within the same organ or tissue. Now, the National Institutes of Health (NIH) has launched a 5-year, $140 million project to map this universe of genomic diversity—and probe why it matters. Featuring YSM's Flora Vaccarino.
- August 14, 2023Source: Healthline Media
A new study has highlighted an association between neurodevelopmental abnormalities and autism development.
- August 11, 2023Source: U.S. News & World Report
Research using three-dimensional replicas of the developing brain created in a lab dish is shedding new light on autism spectrum disorder.
- August 10, 2023Source: YaleNews
Two distinct abnormalities that arise just weeks after the start of brain development have been associated with the emergence of autism spectrum disorder. The study was co-led by Alexandre Jourdon, Feinan Wu, and Jessica Mariani, all from the Kavli Institute affiliated lab of Flora Vaccarino at Yale School of Medicine.
- August 10, 2023Source: Springer Nature
"Modeling idiopathic autism in forebrain organoids reveals an imbalance of excitatory cortical neuron subtypes during early neurogenesis"
- June 05, 2023Source: For all issues, please visit: https://www.libd.org/neurodevelopments/
Through the genomic sands of time Archaic genomes provide insights into human brain evolution and disease