Henk De Feyter, PhD
Associate Professor of Radiology and Biomedical ImagingDownloadHi-Res Photo
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Associate Professor of Radiology and Biomedical Imaging
Appointments
Radiology & Biomedical Imaging
Associate Professor on TermPrimary
Other Departments & Organizations
- Bioimaging Sciences
- Deuterium Metabolic Imaging (DMI)
- Developmental Therapeutics
- Magnetic Resonance Research Center
- Magnetic Resonance Spectroscopy
- MR Center
- Radiology & Biomedical Imaging
- Yale Cancer Center
Education & Training
- Postdoctoral Associate
- Yale University (2010)
- PhD
- Eindhoven University of Technology, Department of Biomedical Engineering
- MSc
- Maastricht University, Department of Health, Medicine and Life Sciences
- MSc
- Ghent University, DEPARTMENT OF REHABILITATION SCIENCES
Research
Overview
Medical Subject Headings (MeSH)
Biomarkers, Tumor; Magnetic Resonance Spectroscopy; Metabolic Networks and Pathways
ORCID
0000-0001-6111-0316
Research at a Glance
Yale Co-Authors
Frequent collaborators of Henk De Feyter's published research.
Publications Timeline
A big-picture view of Henk De Feyter's research output by year.
Research Interests
Research topics Henk De Feyter is interested in exploring.
Robin de Graaf, PhD
Richard Carson, PhD
Robert Fulbright, MD
Anita Huttner, MD
Antonio Omuro, MD
Barbara Gulanski, MD, MPH
30Publications
1,441Citations
Magnetic Resonance Spectroscopy
Publications
2024
High-quality lipid suppression and B0 shimming for human brain 1H MRSI
Kumaragamage C, McIntyre S, Nixon T, De Feyter H, de Graaf R. High-quality lipid suppression and B0 shimming for human brain 1H MRSI. NeuroImage 2024, 300: 120845. PMID: 39276817, DOI: 10.1016/j.neuroimage.2024.120845.Peer-Reviewed Original ResearchAltmetricConceptsOuter volume suppressionInner volume selectionSlice coverageField shimmingLipid suppressionMRSI acquisitionMagnetic field shimmingMagnetic resonance spectroscopic imagingSpherical harmonic fieldsBrain non-invasivelyAxial coverageMulti-coilRadio frequencyVolume suppressionB0 shimmingBrain coverageGradient coilsHarmonic fieldVolume selectionGradient insertShimming performancePhantom experimentsField variationsSpectroscopic imagingProton magnetic resonance spectroscopic imagingLipid removal in deuterium metabolic imaging (DMI) using spatial prior knowledge
de Graaf R, Liu Y, Corbin Z, De Feyter H. Lipid removal in deuterium metabolic imaging (DMI) using spatial prior knowledge. Magnetic Resonance 2024, 5: 21-31. DOI: 10.5194/mr-5-21-2024.Peer-Reviewed Original ResearchAltmetric
2023
Intrathecal delivery of nanoparticle PARP inhibitor to the cerebrospinal fluid for the treatment of metastatic medulloblastoma
Khang M, Lee J, Lee T, Suh H, Lee S, Cavaliere A, Rushing A, Geraldo L, Belitzky E, Rossano S, de Feyter H, Shin K, Huttner A, Roussel M, Thomas J, Carson R, Marquez-Nostra B, Bindra R, Saltzman W. Intrathecal delivery of nanoparticle PARP inhibitor to the cerebrospinal fluid for the treatment of metastatic medulloblastoma. Science Translational Medicine 2023, 15: eadi1617. PMID: 37910601, PMCID: PMC11078331, DOI: 10.1126/scitranslmed.adi1617.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsCerebrospinal fluidDelivery of drugsEffective therapyTherapeutic indexPARP inhibitorsBlood-brain barrierSite of tumorRapid systemic clearanceXenograft mouse modelSolvent evaporation processAdministration of substancesLeptomeningeal spreadIntrathecal deliveryLeptomeningeal metastasesBrain penetrationSystemic clearanceTumor regressionPolymer nanoparticlesMetastatic medulloblastomaMouse modelPediatric medulloblastomaDrug accumulationCSF turnoverEncapsulated drugsPET imagingImaging metabolism of deuterated glucose in patients with primary brain tumors
Corbin Z, Liu Y, Fulbright R, Thaw-Poon S, Baehring J, Blondin N, Kim P, Omuro A, Chiang V, Moliterno J, Omay S, Piepmeier J, Rothman D, de Graaf R, De Feyter H. Imaging metabolism of deuterated glucose in patients with primary brain tumors. Proceedings Of The International Society For Magnetic Resonance In Medicine ... Scientific Meeting And Exhibition. 2023 DOI: 10.58530/2023/0142.Peer-Reviewed Original ResearchIn vivo demonstration of arbitrary ROI shaping and B0 shimming with MC-ECLIPSE for applications in human brain proton MRSI
Kumaragamage C, McIntyre S, Nixon T, De Feyter H, de Graaf R. In vivo demonstration of arbitrary ROI shaping and B0 shimming with MC-ECLIPSE for applications in human brain proton MRSI. Proceedings Of The International Society For Magnetic Resonance In Medicine ... Scientific Meeting And Exhibition. 2023 DOI: 10.58530/2023/1238.Peer-Reviewed Original ResearchParallel Proton and Deuterium Metabolic Imaging
Liu Y, Kumaragamage C, Nixon T, McIntyre S, De Feyter H, de Graaf R. Parallel Proton and Deuterium Metabolic Imaging. Proceedings Of The International Society For Magnetic Resonance In Medicine ... Scientific Meeting And Exhibition. 2023 DOI: 10.58530/2023/3870.Peer-Reviewed Original ResearchExpanding interleaved MRI-DMI to 3D SWI (Susceptibility Weighted Imaging) : A truncated acquisition approach
Liu Y, Corbin Z, Fulbright R, Nixon T, McIntyre S, De Feyter H, de Graaf R. Expanding interleaved MRI-DMI to 3D SWI (Susceptibility Weighted Imaging) : A truncated acquisition approach. Proceedings Of The International Society For Magnetic Resonance In Medicine ... Scientific Meeting And Exhibition. 2023 DOI: 10.58530/2023/0013.Peer-Reviewed Original ResearchConceptsRobust and Automated Processing of Deuterium Metabolic Imaging (DMI) using Spatial Prior Knowledge
de Graaf R, Liu Y, Corbin Z, De Feyter H. Robust and Automated Processing of Deuterium Metabolic Imaging (DMI) using Spatial Prior Knowledge. Proceedings Of The International Society For Magnetic Resonance In Medicine ... Scientific Meeting And Exhibition. 2023 DOI: 10.58530/2023/4107.Peer-Reviewed Original ResearchIndirect detection of deuterated glucose brain metabolism at 3 Tesla: preliminary findings in volunteers and patients with gliomas
Autry A, LaFontaine M, Villanueva-Meyer J, Chang S, de Feyter H, Li Y. Indirect detection of deuterated glucose brain metabolism at 3 Tesla: preliminary findings in volunteers and patients with gliomas. Proceedings Of The International Society For Magnetic Resonance In Medicine ... Scientific Meeting And Exhibition. 2023 DOI: 10.58530/2023/2502.Peer-Reviewed Original ResearchConceptsIndirect detectionMagnetic resonance spectroscopic imagingAnterior cingulate cortexSingle-voxel spectroscopyGlucose metabolismLevels of glutamateSpectroscopic imagingReduced levels of glutamateGlucose brain metabolismT2 lesionsHealthy subjectsCingulate cortexBrain tumorsTeslaPatientsBrain metabolismGray matterPreliminary dataReduced levelsMetabolismMapping of exogenous choline uptake and metabolism in rat glioblastoma using deuterium metabolic imaging (DMI)
Ip K, Thomas M, Behar K, de Graaf R, De Feyter H. Mapping of exogenous choline uptake and metabolism in rat glioblastoma using deuterium metabolic imaging (DMI). Frontiers In Cellular Neuroscience 2023, 17: 1130816. PMID: 37187610, PMCID: PMC10175635, DOI: 10.3389/fncel.2023.1130816.Peer-Reviewed Original ResearchCitationsAltmetricConceptsBrain tumorsNormal brainHigh tumorCholine uptakeRG2 cellsCholine infusionMetabolic imagingExogenous cholineMetabolic imaging techniquesDeuterium metabolic imagingIntravenous infusionRG2 tumorsTumor lesionsAnimal modelsCholine metabolismTumorsInfusionRat glioblastomaIntracellular cholineFree cholineHigh uptakeLesionsCholineRatsDeuterated choline
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