2023
Does Cognitive-Behavioral Therapy for Youth Anxiety Disorders Improve Social Functioning and Peer Relationships?
Etkin R, Juel E, Lebowitz E, Silverman W. Does Cognitive-Behavioral Therapy for Youth Anxiety Disorders Improve Social Functioning and Peer Relationships? Clinical Child And Family Psychology Review 2023, 26: 1052-1076. PMID: 37838627, DOI: 10.1007/s10567-023-00454-3.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMeSH KeywordsAdolescentAnxietyAnxiety DisordersChildCognitive Behavioral TherapyHumansSocial InteractionTreatment OutcomeConceptsCognitive behavioral therapyAdolescent anxiety disordersPeer relationshipsSocial functioningAnxiety disordersYouth anxiety disordersPeer outcomesAnxiety reductionTreatment-specific effectsFunctioningTreatment specificitySystematic narrative reviewRelated difficultiesSample characteristicsMajority of studiesSpecific outcomesChildrenTreatment outcomesStatistical findingsStudy sampleDisordersNarrative reviewFindingsRelationshipAnxietyEffect modification of an effective transdiagnostic cognitive behavioral psychotherapy in youths with common mental health problems: Secondary analyses of the randomized mind-my-mind trial
Rimvall M, Vassard D, Nielsen S, Wolf R, Plessen K, Bilenberg N, Thomsen P, Thastum M, Neumer S, Puggaard L, Pedersen M, Pagsberg A, Silverman W, Correll C, Christensen R, Jeppesen P. Effect modification of an effective transdiagnostic cognitive behavioral psychotherapy in youths with common mental health problems: Secondary analyses of the randomized mind-my-mind trial. European Neuropsychopharmacology 2023, 74: 64-75. PMID: 37279641, DOI: 10.1016/j.euroneuro.2023.05.004.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentCognitionCognitive Behavioral TherapyEmotionsHumansMental DisordersMental HealthTreatment OutcomeConceptsMental health problemsPotential effect modifiersHealth problemsDifferential treatment effectsTreatment benefitEffect modifiersUntreated mental health problemsSubstantial mental health problemsCommon mental health problemsTreatment effectsLocal community settingsCommunity-based programsBaseline factorsTreat analysisClinical variablesEffect modificationCognitive-behavioral psychotherapyDiagnostic criteriaMIND trialSociodemographic factorsTrial dataMental disordersSecondary analysisCommunity settingsCBT treatmentParent Accommodation Contemporaneously Mediates the Association Between Youth Irritability and Youth Anxiety Treatment Outcome
Cabrera V, Buitron V, Patriarca G, Rey Y, Lebowitz E, Silverman W, Pettit J. Parent Accommodation Contemporaneously Mediates the Association Between Youth Irritability and Youth Anxiety Treatment Outcome. Behavior Therapy 2023, 54: 852-862. PMID: 37597962, PMCID: PMC10440415, DOI: 10.1016/j.beth.2023.03.002.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAnxietyAnxiety DisordersChildCognitive Behavioral TherapyFemaleHumansMaleParentsTreatment OutcomeConceptsYouth anxiety severityParent accommodationCognitive-behavioral treatmentYouth irritabilityAnxiety treatment outcomesAnxiety severityChild anxietyPrimary anxiety disorder diagnosisAnxiety disorder diagnosisAnxious youthYouth anxietyYouth ages 6Adolescent irritabilityAnxiety outcomesBehavioral treatmentAnxiety protocolAnxietyGreater impairmentDisorder diagnosisAge 6Treatment outcomesFuture researchPosttreatmentIrritabilityResearch documents
2022
Parent Involvement Enhances CBTs for Anxiety Disorders in Hispanic/Latino Youth: Acculturation as a Moderator
Patriarca G, Rey Y, Marin C, Yeguez C, Pettit J, Silverman W. Parent Involvement Enhances CBTs for Anxiety Disorders in Hispanic/Latino Youth: Acculturation as a Moderator. Journal Of Consulting And Clinical Psychology 2022, 90: 827-836. PMID: 36355650, PMCID: PMC9727821, DOI: 10.1037/ccp0000770.Peer-Reviewed Original ResearchMeSH KeywordsAcculturationAdolescentAnxiety DisordersChildCognitive Behavioral TherapyFemaleHispanic or LatinoHumansMaleParentsConceptsCognitive-behavioral treatmentAnxiety outcomesParent acculturationAnxiety disordersPsychological controlNegative reinforcementEfficacy of CBTParents’ psychological controlYouth anxiety severityHispanic/Latino youthEvidence-based interventionsYouth ages 6Anxiety severityBehavioral treatmentParents' useLatino youthLatino familiesParent involvementAge 6YouthAcculturation levelAcculturationEnculturationModeratorDisordersMitigating Multiple Sources of Bias in a Quasi-Experimental Integrative Data Analysis: Does Treating Childhood Anxiety Prevent Substance Use Disorders in Late Adolescence/Young Adulthood?
Saavedra LM, Morgan-López AA, West SG, Alegría M, Silverman WK. Mitigating Multiple Sources of Bias in a Quasi-Experimental Integrative Data Analysis: Does Treating Childhood Anxiety Prevent Substance Use Disorders in Late Adolescence/Young Adulthood? Prevention Science 2022, 24: 1622-1635. PMID: 36057023, DOI: 10.1007/s11121-022-01422-z.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAnxietyAnxiety DisordersChildChild Behavior DisordersCognitive Behavioral TherapyHumansRandomized Controlled Trials as TopicSubstance-Related DisordersYoung AdultConceptsStudy-related treatmentYoung adulthoodPropensity scoreLong-term followDrug use disordersAdolescence/young adulthoodQuasi-experimental designLate adolescence/young adulthoodClinical trialsSubstance use disorder severityLong-term effectsChild anxiety disordersEpidemiological studiesIntegrative data analysisAnxiety disorder treatmentUse disordersDisorder treatmentAnxiety disordersControl participantsEpidemiological sampleClinical samplesDisorder severityTrialsLong-term assessmentDisordersAge and depressive symptoms change predict the 4‐year self‐concept trajectory for youth after anxiety treatment
Fjermestad KW, Bellika K, Matre C, Silverman WK, Wergeland GJ. Age and depressive symptoms change predict the 4‐year self‐concept trajectory for youth after anxiety treatment. Journal Of Clinical Psychology 2022, 78: 2109-2121. PMID: 35975330, PMCID: PMC9804830, DOI: 10.1002/jclp.23427.Peer-Reviewed Original ResearchAdolescentAnxietyAnxiety DisordersCognitive Behavioral TherapyDepressionFemaleHumansMaleSelf ConceptAttention Training as a Low-Intensity Treatment for Concerning Anxiety in Clinic-Referred Youth
Pettit J, Rey Y, Marin C, Bechor M, Lebowitz E, Vasey M, Jaccard J, Abend R, Pine D, Bar-Haim Y, Silverman W. Attention Training as a Low-Intensity Treatment for Concerning Anxiety in Clinic-Referred Youth. Behavior Therapy 2022, 54: 77-90. PMID: 36608979, PMCID: PMC9825787, DOI: 10.1016/j.beth.2022.07.004.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAnxietyAnxiety DisordersAttentional BiasChildChild, PreschoolCognitive Behavioral TherapyHumansMaleTreatment OutcomeConceptsAttention Bias Modification TreatmentAttention control trainingAttention trainingAnxiety severityAttention controlAnxiety levelsAttention biasNeutral facesLow-intensity treatmentGlobal impairmentDot-probe taskYouth anxiety severityClinic-Referred YouthFull criteriaAttention focusingControl trainingTreatment researchYouthIndependent evaluatorsTrainingImpairment ratingsACT trialsPosttreatmentSeverity ratingsRatingsYouth social functioning interacts with treatment arm, diagnosis, and gender to predict anxiety treatment outcome
Etkin RG, Marin CE, Silverman WK, Lebowitz ER. Youth social functioning interacts with treatment arm, diagnosis, and gender to predict anxiety treatment outcome. Behaviour Research And Therapy 2022, 156: 104160. PMID: 35870327, DOI: 10.1016/j.brat.2022.104160.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAnxietyAnxiety DisordersCognitive Behavioral TherapyFemaleHumansMaleSocial InteractionTreatment OutcomeConceptsAnxiety treatment outcomesYouth social functioningSocial skillsPositive social interactionsSocial functioningAnxiety diagnosesAnxiety disordersSocial interactionParent-based treatmentChildren's social skillsSocial anxiety disorderYouths' social skillsAnxiety symptom severityYouth genderTreatment outcomesDiagnostic InterviewSymptom severityClinical functioningFunctioningSkillsYouthPredictorsMultiple regression modelDisordersGender
2021
Effectiveness of Transdiagnostic Cognitive-Behavioral Psychotherapy Compared With Management as Usual for Youth With Common Mental Health Problems
Jeppesen P, Wolf RT, Nielsen SM, Christensen R, Plessen KJ, Bilenberg N, Thomsen PH, Thastum M, Neumer SP, Puggaard LB, Pedersen M, Pagsberg AK, Silverman WK, Correll CU. Effectiveness of Transdiagnostic Cognitive-Behavioral Psychotherapy Compared With Management as Usual for Youth With Common Mental Health Problems. JAMA Psychiatry 2021, 78: 250-260. PMID: 33355633, PMCID: PMC7758821, DOI: 10.1001/jamapsychiatry.2020.4045.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAnxietyBehavioral SymptomsChildCognitive Behavioral TherapyDenmarkDepressionDisease ManagementFemaleFollow-Up StudiesHumansMaleOutcome Assessment, Health CareConceptsMental health problemsCommon mental health problemsHealth problemsMAU groupSecondary outcomesWeek 26Clinical trialsWeek 18Depressive symptomsPrimary outcome dataMain inclusion criteriaNumber of respondersMental health careBehavioral problemsHelp-seeking youthCognitive behavioral therapy programParent-reported changesTreat populationUsual carePrimary outcomeManualized CBTCognitive-behavioral psychotherapyInclusion criteriaMAIN OUTCOMEBehavioral disturbancesModerators of response to child‐based and parent‐based child anxiety treatment: a machine learning‐based analysis
Lebowitz ER, Zilcha‐Mano S, Orbach M, Shimshoni Y, Silverman WK. Moderators of response to child‐based and parent‐based child anxiety treatment: a machine learning‐based analysis. Journal Of Child Psychology And Psychiatry 2021, 62: 1175-1182. PMID: 33624848, DOI: 10.1111/jcpp.13386.Peer-Reviewed Original ResearchMeSH KeywordsAnxietyAnxiety DisordersChildCognitive Behavioral TherapyHumansMachine LearningParentingTreatment OutcomeConceptsModerators of responseParent negativityChild anxiety treatmentOxytocin levelsBaseline anxietyCognitive behavioral therapyPrimary anxiety disorderChild-reported outcomesParent-reported outcomesChildhood anxietyAnxiety treatmentAnxiety symptomsPotential moderatorsAnxiety disordersTreatment conditionsModeratorMachine learning-based analysisAnxietyNegativitySignificant interactionChildrenNonoptimal treatmentTreatment efficacyParentingSocioemotional
2020
Parent-Child Agreement on Family Accommodation Differentially Predicts Outcomes of Child-Based and Parent-Based Child Anxiety Treatment
Zilcha-Mano S, Shimshoni Y, Silverman WK, Lebowitz ER. Parent-Child Agreement on Family Accommodation Differentially Predicts Outcomes of Child-Based and Parent-Based Child Anxiety Treatment. Journal Of Clinical Child & Adolescent Psychology 2020, 50: 427-439. PMID: 32401557, PMCID: PMC8496486, DOI: 10.1080/15374416.2020.1756300.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAnxietyChildCognitive Behavioral TherapyFemaleHumansMaleParent-Child RelationsParentingTreatment OutcomeConceptsParent-child agreementFamily accommodationMultilevel response-surface analysisAnxious Childhood EmotionsChild anxiety treatmentChild anxiety severityCognitive behavioral therapyAnxiety symptom severityDistinct underlying mechanismsChildhood EmotionsChildhood anxietySupportive parentingAnxiety treatmentParent reportBehavioral therapyRole of accommodationAnxiety severityAnxiety disordersPoor treatment outcomesTreatment outcomesSymptom severitySubsequent treatment outcomesTreatment endSignificant predictorsChildren
2019
Latino and Non-Latino Parental Treatment Preferences for Child and Adolescent Anxiety Disorders
Seligman LD, Hovey JD, Ibarra M, Hurtado G, Marin CE, Silverman WK. Latino and Non-Latino Parental Treatment Preferences for Child and Adolescent Anxiety Disorders. Child Psychiatry & Human Development 2019, 51: 617-624. PMID: 31807934, DOI: 10.1007/s10578-019-00945-x.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAnxietyAnxiety DisordersChildCognitive Behavioral TherapyFemaleHispanic or LatinoHumansParentsConceptsCognitive behavioral therapyLatino parentsChild anxietyNon-Latino white parentsAdolescent anxiety disordersParental involvementParental treatment preferencesPerception of burdenMental health treatmentNon-Latino parentsPotential treatment barriersYouth anxietyBehavioral therapyAnxiety disordersChild's treatmentParent involvementTreatment involvementAnxietyHealth treatmentWhite parentsTreatment barriersParents' preferencesGreater preferenceParentsCurrent studyEfficacy and mechanisms underlying a gamified attention bias modification training in anxious youth: protocol for a randomized controlled trial
Linke JO, Jones E, Pagliaccio D, Swetlitz C, Lewis KM, Silverman WK, Bar-Haim Y, Pine DS, Brotman MA. Efficacy and mechanisms underlying a gamified attention bias modification training in anxious youth: protocol for a randomized controlled trial. BMC Psychiatry 2019, 19: 246. PMID: 31391027, PMCID: PMC6686536, DOI: 10.1186/s12888-019-2224-2.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAmygdalaAnxiety DisordersAttentional BiasChildCognitive Behavioral TherapyFemaleHumansMagnetic Resonance ImagingMaleRandomized Controlled Trials as TopicTreatment OutcomeVideo GamesConceptsCognitive behavioral therapyContext of CBTBias modification trainingDot-probe taskAttentional biasAnxious youthAmygdala connectivityAnxiety disordersAttention bias modification trainingPrimary anxiety disorder diagnosisHealthy comparison youthAnxiety disorder diagnosisVisual searchThreat responsesNeurobiological correlatesComparison youthBehavioral therapyTraining elementsDisorder diagnosisEngaging gameNeuronal levelYouthPrevious findingsMixed resultsTaskA genome-wide association meta-analysis of prognostic outcomes following cognitive behavioural therapy in individuals with anxiety and depressive disorders
Rayner C, Coleman JRI, Purves KL, Hodsoll J, Goldsmith K, Alpers GW, Andersson E, Arolt V, Boberg J, Bögels S, Creswell C, Cooper P, Curtis C, Deckert J, Domschke K, El Alaoui S, Fehm L, Fydrich T, Gerlach AL, Grocholewski A, Hahlweg K, Hamm A, Hedman E, Heiervang ER, Hudson JL, Jöhren P, Keers R, Kircher T, Lang T, Lavebratt C, Lee SH, Lester KJ, Lindefors N, Margraf J, Nauta M, Pané-Farré CA, Pauli P, Rapee RM, Reif A, Rief W, Roberts S, Schalling M, Schneider S, Silverman WK, Ströhle A, Teismann T, Thastum M, Wannemüller A, Weber H, Wittchen HU, Wolf C, Rück C, Breen G, Eley TC. A genome-wide association meta-analysis of prognostic outcomes following cognitive behavioural therapy in individuals with anxiety and depressive disorders. Translational Psychiatry 2019, 9: 150. PMID: 31123309, PMCID: PMC6533285, DOI: 10.1038/s41398-019-0481-y.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnxiety DisordersChildCognitive Behavioral TherapyDepressive Disorder, MajorGenome-Wide Association StudyHumansOutcome Assessment, Health CareConceptsCognitive behavioral therapyBehavioral therapyAnxiety disordersTherapy outcomeEvidence-based treatmentsPolygenic scoringMajor depressive disorderGenome-wide association studiesDepressive disorderGenome-wide associationStrong genetic correlationCommon genetic variantsComplex traitsSingle nucleotide polymorphismsWide associationStrongest predictorPsychopathologyAnxietyPersonalityGenetic overlapAssociation studiesGenetic correlationsGenetic variantsNucleotide polymorphismsDisordersA Randomized Controlled Trial of Attention Bias Modification Treatment in Youth With Treatment-Resistant Anxiety Disorders
Pettit JW, Bechor M, Rey Y, Vasey MW, Abend R, Pine DS, Bar-Haim Y, Jaccard J, Silverman WK. A Randomized Controlled Trial of Attention Bias Modification Treatment in Youth With Treatment-Resistant Anxiety Disorders. Journal Of The American Academy Of Child & Adolescent Psychiatry 2019, 59: 157-165. PMID: 30877049, PMCID: PMC6744353, DOI: 10.1016/j.jaac.2019.02.018.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAnxietyAnxiety DisordersAttentional BiasChildCognitive Behavioral TherapyFemaleHumansMaleTreatment OutcomeConceptsAttention Bias Modification TreatmentAttention control trainingTreatment-resistant anxiety disordersAttention controlAnxiety severityAttention biasNeutral facesAnxiety disordersAttention bias modification trainingBias modification trainingYouth anxiety severityCognitive behavioral therapyAttention trainingDiagnostic recoveryAnxiety diagnosesControl trainingTraining trialsContingency scheduleYouthModification treatmentIndependent evaluatorsAnxietyTrainingAugmentation strategiesFaceParent-Based Treatment as Efficacious as Cognitive-Behavioral Therapy for Childhood Anxiety: A Randomized Noninferiority Study of Supportive Parenting for Anxious Childhood Emotions
Lebowitz ER, Marin C, Martino A, Shimshoni Y, Silverman WK. Parent-Based Treatment as Efficacious as Cognitive-Behavioral Therapy for Childhood Anxiety: A Randomized Noninferiority Study of Supportive Parenting for Anxious Childhood Emotions. Journal Of The American Academy Of Child & Adolescent Psychiatry 2019, 59: 362-372. PMID: 30851397, PMCID: PMC6732048, DOI: 10.1016/j.jaac.2019.02.014.Peer-Reviewed Original ResearchMeSH KeywordsAnxietyAnxiety DisordersChildCognitionCognitive Behavioral TherapyFemaleHumansMaleMiddle AgedParentingTreatment OutcomeConceptsParent-based treatmentAnxious Childhood EmotionsChildhood anxiety disordersFamily accommodationChildhood anxietyAnxiety disordersChildhood EmotionsSupportive parentingParenting stressAnxiety outcomesCognitive behavioral therapyPrimary anxiety disorderParent interventionBehavioral therapyChildren's ratingsAnxiety severityTreatment credibilityClinician-rated scalesParent treatmentParent involvementAnxietyDiagnostic InterviewEmotionsParentingIndependent evaluatorsTrajectories and Predictors of Response in Youth Anxiety CBT: Integrative Data Analysis
Skriner LC, Chu BC, Kaplan M, Bodden DHM, Bögels SM, Kendall PC, Nauta MH, Silverman WK, Wood JJ, Barker DH, de la Torre J, Saavedra L, Xie MG. Trajectories and Predictors of Response in Youth Anxiety CBT: Integrative Data Analysis. Journal Of Consulting And Clinical Psychology 2019, 87: 198-211. PMID: 30570308, DOI: 10.1037/ccp0000367.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAnxiety DisordersChildCognitive Behavioral TherapyFemaleHumansMaleTreatment OutcomeConceptsCognitive behavioral therapyGrowth mixture modelingIntegrative data analysisParent-reported anxiety symptomsFamily cognitive-behavioral therapySymptom changeTrajectory classesYouth-reported symptomsParent-reported symptomsMixture modelingPredictors of trajectoriesItem response theory modelsAnxious youthImprovement classesAnxiety symptomsRapid respondersResponse classesYouthTheory modelPredictorsDistinct patternsOlder agePredictors of responseMembershipSymptomsA Cost Analysis of a Stepped Care Treatment Approach for Anxiety Disorders in Youth
Yeguez CE, Page TF, Rey Y, Silverman WK, Pettit JW. A Cost Analysis of a Stepped Care Treatment Approach for Anxiety Disorders in Youth. Journal Of Clinical Child & Adolescent Psychology 2019, 49: 549-555. PMID: 30644757, PMCID: PMC6629529, DOI: 10.1080/15374416.2018.1539913.Peer-Reviewed Original ResearchAnxiety DisordersChildCognitive Behavioral TherapyCost-Benefit AnalysisFemaleHumansMaleTreatment OutcomeThe Back2School modular cognitive behavioral intervention for youths with problematic school absenteeism: study protocol for a randomized controlled trial
Thastum M, Johnsen DB, Silverman WK, Jeppesen P, Heyne DA, Lomholt JJ. The Back2School modular cognitive behavioral intervention for youths with problematic school absenteeism: study protocol for a randomized controlled trial. Trials 2019, 20: 29. PMID: 30621787, PMCID: PMC6325742, DOI: 10.1186/s13063-018-3124-3.Peer-Reviewed Original ResearchMeSH KeywordsAbsenteeismAdolescentChildChild Behavior DisordersCognitive Behavioral TherapyHumansOutcome Assessment, Health CareQuality of LifeRandomized Controlled Trials as TopicResearch DesignConceptsModular cognitive behavioral interventionCognitive behavioral therapy interventionManualized treatment programCognitive-behavioral interventionsBehavioral therapy interventionProblematic school absenteeismInitial effectivenessTeacher-parent collaborationSchool attendancePsychosocial functioningTeacher reportsAcademic difficultiesPsychological problemsDisruptive behaviorBehavioral interventionsTherapy interventionTreatment programQuality of lifeSixty childrenSchool dropoutYouthSecondary outcomesPrimary outcomeControl armRisk factors
2018
The impact of treatment delivery format on response to cognitive behaviour therapy for preadolescent children with anxiety disorders
McKinnon A, Keers R, Coleman JRI, Lester KJ, Roberts S, Arendt K, Bögels SM, Cooper P, Creswell C, Hartman CA, Fjermestad KW, In‐Albon T, Lavallee K, Lyneham HJ, Smith P, Meiser‐Stedman R, Nauta MH, Rapee RM, Rey Y, Schneider S, Silverman WK, Thastum M, Thirlwall K, Wergeland GJ, Eley TC, Hudson JL. The impact of treatment delivery format on response to cognitive behaviour therapy for preadolescent children with anxiety disorders. Journal Of Child Psychology And Psychiatry 2018, 59: 763-772. PMID: 29520926, PMCID: PMC6055633, DOI: 10.1111/jcpp.12872.Peer-Reviewed Original ResearchConceptsIndividual cognitive behavior therapyGroup cognitive behavior therapyCognitive behavior therapyGeneralised anxiety disorderSeparation anxiety disorderSpecific phobiaAnxiety disordersPrimary anxiety diagnosisClinical benefitClinical severityDSM-IV psychiatric disordersAnxiety diagnosesRate of remissionAdditional clinical benefitGreater clinical benefitBehavior therapySemistructured clinical interviewRemission responseDelivery formatPrimary diagnosisTreatment delivery formatPsychiatric disordersClinical InterviewCBT trialsTreatment format