Genome-wide association study of response to cognitive–behavioural therapy in children with anxiety disorders
Coleman JR, Lester KJ, Keers R, Roberts S, Curtis C, Arendt K, Bögels S, Cooper P, Creswell C, Dalgleish T, Hartman CA, Heiervang ER, Hötzel K, Hudson JL, In-Albon T, Lavallee K, Lyneham HJ, Marin CE, Meiser-Stedman R, Morris T, Nauta MH, Rapee RM, Schneider S, Schneider SC, Silverman WK, Thastum M, Thirlwall K, Waite P, Wergeland GJ, Breen G, Eley TC. Genome-wide association study of response to cognitive–behavioural therapy in children with anxiety disorders. The British Journal Of Psychiatry 2016, 209: 236-243. PMID: 26989097, PMCID: PMC5007453, DOI: 10.1192/bjp.bp.115.168229.Peer-Reviewed Original ResearchGenetic variation in the endocannabinoid system and response to Cognitive Behavior Therapy for child anxiety disorders
Lester KJ, Coleman JR, Roberts S, Keers R, Breen G, Bögels S, Creswell C, Hudson JL, McKinnon A, Nauta M, Rapee RM, Schneider S, Silverman WK, Thastum M, Waite P, Wergeland GJ, Eley TC. Genetic variation in the endocannabinoid system and response to Cognitive Behavior Therapy for child anxiety disorders. American Journal Of Medical Genetics Part B Neuropsychiatric Genetics 2016, 174: 144-155. PMID: 27346075, PMCID: PMC5324578, DOI: 10.1002/ajmg.b.32467.Peer-Reviewed Original ResearchConceptsAnxiety disorder diagnosisIndividual differencesPrimary anxiety disorder diagnosisSuccessful psychological treatmentDisorder diagnosisCognitive behavior therapyAnxiety disorder severityExtinction learningFear extinctionPsychological treatmentBehavior therapyDisorder severityPoor treatment responseSymptom severityEffect sizeFull sampleEndocannabinoid systemFearTreatment responseCBTAnxietyPotential clinical utilityLimited evidenceLearningChildren