2022
The effects of stimulant dose and dosing strategy on treatment outcomes in attention-deficit/hyperactivity disorder in children and adolescents: a meta-analysis
Farhat LC, Flores JM, Behling E, Avila-Quintero VJ, Lombroso A, Cortese S, Polanczyk GV, Bloch MH. The effects of stimulant dose and dosing strategy on treatment outcomes in attention-deficit/hyperactivity disorder in children and adolescents: a meta-analysis. Molecular Psychiatry 2022, 27: 1562-1572. PMID: 35027679, DOI: 10.1038/s41380-021-01391-9.Peer-Reviewed Original ResearchConceptsFixed-dose trialAttention-deficit/hyperactivity disorderDose-limiting adverse eventsChildren/adolescentsAdverse eventsFlexible-dose trialTerms of efficacyClinical practiceHigh dosesFlexible dose designIntolerable adverse eventsHyperactivity disorderIncremental benefitLikelihood of discontinuationADHD symptomsLarge systematic reviewSchool-aged children/adolescentsFlexible titrationPotential long-term effectsSymptom controlTreatment discontinuationClinical outcomesStimulant dosesDaily dosesClinical guidelines
2021
Palliative Care for Patients on Extracorporeal Membrane Oxygenation for COVID-19 Infection
Rao A, Zaaqoq AM, Kang IG, Vaughan EM, Flores J, Avila-Quintero VJ, Alnababteh MH, Kelemen AM, Groninger H. Palliative Care for Patients on Extracorporeal Membrane Oxygenation for COVID-19 Infection. American Journal Of Hospice And Palliative Medicine® 2021, 38: 854-860. PMID: 33685240, PMCID: PMC7944020, DOI: 10.1177/10499091211001009.Peer-Reviewed Original ResearchConceptsExtracorporeal membrane oxygenationPalliative care consultationCOVID-19 infectionPalliative care teamYears of ageCare consultationsPalliative careMembrane oxygenationIll patientsHigh morbidityCare teamNon-pain symptom managementOdds of deathPatients/familiesRates of anxietyAcademic medical centerSurrogate decision makersSymptom controlPatient characteristicsPain managementCase seriesClinical outcomesSymptom managementMedical complexityMedical Center