2014
NAP Reduces Murine Microvascular Endothelial Cells Proliferation Induced by Hyperglycemia
D’Amico A, Scuderi S, Maugeri G, Cavallaro S, Drago F, D’Agata V. NAP Reduces Murine Microvascular Endothelial Cells Proliferation Induced by Hyperglycemia. Journal Of Molecular Neuroscience 2014, 54: 405-413. PMID: 24874579, DOI: 10.1007/s12031-014-0335-2.Peer-Reviewed Original ResearchConceptsProtein kinase/extracellular signal-regulated protein kinaseExtracellular signal-regulated protein kinaseMitogen-activated protein kinase/extracellular signal-regulated protein kinaseSignal-regulated protein kinaseKinase/Akt pathwayEndothelial cell proliferationPhosphatidylinositol-3-kinase/Akt pathwayCell proliferationProtein expression analysisProtein kinaseExpression analysisBiological roleAkt pathwayPhosphorylation levelsTime-dependent mannerHigh glucoseMurine microvascular endothelial cellsMicrovascular endothelial cell proliferationMicrovascular endothelial cellsEndothelial cellsProliferationMTT assayCells
2013
Antiproliferative Effects of PACAP and VIP in Serum-Starved Glioma Cells
D’Amico A, Scuderi S, Saccone S, Castorina A, Drago F, D’Agata V. Antiproliferative Effects of PACAP and VIP in Serum-Starved Glioma Cells. Journal Of Molecular Neuroscience 2013, 51: 503-513. PMID: 23900722, DOI: 10.1007/s12031-013-0076-7.Peer-Reviewed Original ResearchConceptsPituitary adenylate cyclase-activating polypeptideVasoactive intestinal peptideCalorie restrictionGlioma cellsCell proliferationEffects of PACAPAdenylate cyclase-activating polypeptideCyclase-activating polypeptideExpression of p53Expression of nestinFormation of metastasesC6 glioma cellsIntestinal peptideAcute conditionsVIP treatmentPrognostic markerExpression of proteinsCell malignanciesGFAP decreasesTumor microenvironmentAntiproliferative effectsCyclin D1Cancer developmentCancer treatmentCancer cells