2024
Beyond the Descriptive: A Comprehensive, Multi-domain Validation of Symptom Trajectories for Individuals at Clinical High Risk for Psychosis
Deng W, Chong B, Addington J, Bearden C, Cadenhead K, Cornblatt B, Keshavan M, Mathalon D, Perkins D, Stone W, Walker E, Woods S, Cannon T. Beyond the Descriptive: A Comprehensive, Multi-domain Validation of Symptom Trajectories for Individuals at Clinical High Risk for Psychosis. Biological Psychiatry Cognitive Neuroscience And Neuroimaging 2024 PMID: 39260565, DOI: 10.1016/j.bpsc.2024.08.020.Peer-Reviewed Original ResearchClinical high riskCHR-PTrajectory groupsMaintenance of symptomsOnset of psychosisNon-convertersHealthy controlsDiagnostic constructSymptom trajectoriesPsychosisAffective comorbiditiesAssess symptomsHeightened riskFunctional impairmentSymptomsEtiological risk factorsFunctional outcomesImminent onsetLevels of intensityRemissionRisk factorsIndividualsPhase 3DistressImpairment
2014
Current status specifiers for patients at clinical high risk for psychosis
Woods SW, Walsh BC, Addington J, Cadenhead KS, Cannon TD, Cornblatt BA, Heinssen R, Perkins DO, Seidman LJ, Tarbox SI, Tsuang MT, Walker EF, McGlashan TH. Current status specifiers for patients at clinical high risk for psychosis. Schizophrenia Research 2014, 158: 69-75. PMID: 25012147, PMCID: PMC4152558, DOI: 10.1016/j.schres.2014.06.022.Peer-Reviewed Original ResearchConceptsNorth American Prodromal Longitudinal StudyClinical high-risk syndromeHigh-risk syndromeCurrent clinical statusPsychosis risk syndromeLongitudinal studyClinical high riskPartial remissionFull remissionClinical statusRemission criteriaRisk syndromeProgression criteriaRole functioningPredictive validityHigh riskRemitted patientsRemissionPatientsCurrent statusSyndromeConvergent validityPsychosisStructured interviewsPresent study