2024
Infants' salivary oxytocin and positive affective reactions to people
Zeng G, Leung T, Maylott S, Malik A, Adornato A, Lebowitz M, Messinger D, Szeto A, Feldman R, Simpson E. Infants' salivary oxytocin and positive affective reactions to people. Hormones And Behavior 2024, 164: 105579. PMID: 38905820, DOI: 10.1016/j.yhbeh.2024.105579.Peer-Reviewed Original ResearchOxytocin levelsSalivary oxytocinFacial affectAffective reactionsEarly Social Communication ScalesInfant positive affectStable individual differencesPositive facial affectSocial Communication ScalesHigher oxytocin levelsPositive affective reactionsSocio-emotional developmentPositive affectIndividual differencesSocial behaviorSmiling womenCommunication ScaleAffectOxytocinPhysiological measuresMonths of ageProsocialityStatistically significant changesU.S. infantsInfantsIntranasal Oxytocin Combined With Social Skills Training for Schizophrenia: An Add-on Randomized Controlled Trial
Saporta-Wiesel L, Feldman R, Levi L, Davidson M, Burshtein S, Gur R, Zagoory-Sharon O, Amiaz R, Park J, Davis J, Weiser M. Intranasal Oxytocin Combined With Social Skills Training for Schizophrenia: An Add-on Randomized Controlled Trial. Schizophrenia Bulletin Open 2024, 5: sgae022. PMID: 39502135, PMCID: PMC11535855, DOI: 10.1093/schizbullopen/sgae022.Peer-Reviewed Original ResearchSocial skills trainingSymptoms of schizophreniaSkills trainingSupportive psychotherapyNegative symptoms of schizophreniaTreatment of negative symptomsSocial interactionBaseline to end-of-studyBlunted affectNegative symptomsPANSS scoresIntranasal oxytocinPositive affectSocial dysfunctionSchizophreniaRandomized controlled trialsTotal scoreSocial behaviorPost hoc analysisPANSSPsychotherapyOxytocinHigh dose oxytocinAffectEnd-of-study
2023
Neurophysin I is an analytically robust surrogate biomarker for oxytocin
MacLean E, Carranza E, Gnanadesikan G, King K, Allen A, Linde-Krieger L, Feldman R, White-Traut R, Hammock E, Carter C, Leng G, Tecot S, Bell A. Neurophysin I is an analytically robust surrogate biomarker for oxytocin. Psychoneuroendocrinology 2023, 161: 106951. PMID: 38194845, PMCID: PMC10872509, DOI: 10.1016/j.psyneuen.2023.106951.Peer-Reviewed Original ResearchSurrogate biomarkerOxytocin concentrationsUseful surrogate biomarkerRegulation of appetitePlasma oxytocin concentrationsNP-1Late pregnancyImmune functionKnockout micePleiotropic neuropeptideUrine samplesPlasma oxytocinCardiovascular repairOxytocinBiomarkersSandwich immunoassayStudy of vasopressinEquimolar concentrationsHuman plasmaBreast milk oxytocin and s-IgA modulate infant biomarkers and social engagement; The role of maternal anxiety
Zagoory-Sharon O, Yirmiya K, Peleg I, Shimon-Raz O, Sanderlin R, Feldman R. Breast milk oxytocin and s-IgA modulate infant biomarkers and social engagement; The role of maternal anxiety. Comprehensive Psychoneuroendocrinology 2023, 17: 100219. PMID: 38187086, PMCID: PMC10765300, DOI: 10.1016/j.cpnec.2023.100219.Peer-Reviewed Original ResearchBreast milkInfant salivaS-IgAInfant biomarkersMaternal anxietyBreast milk compositionMaternal mental healthMother-infant dyadsInfant social behaviorInfant immunityInfant healthSecretory immunoglobulinS-IgA.Mother-infant bondSame biomarkersMental healthAbundant antibodyBiomarkersOxytocinSalivaMental developmentImmunityAssociationDegree of stressHealth