2002
Genetics of Childhood Disorders: XXXV. Autoimmune Disorders, Part 8: Animal Models for Noninflammatory Autoimmune Disorders of the Brain
HALLETT J, KIESSLING L, Lombroso P. Genetics of Childhood Disorders: XXXV. Autoimmune Disorders, Part 8: Animal Models for Noninflammatory Autoimmune Disorders of the Brain. Journal Of The American Academy Of Child & Adolescent Psychiatry 2002, 41: 223-225. PMID: 11837413, DOI: 10.1097/00004583-200202000-00017.Peer-Reviewed Original Research
2001
Genetics of Childhood Disorders: XXXII. Autoimmune Disorders, Part 5: Streptococcal Infection and Autoimmunity, an Epidemiological Perspective
BESSEN D, Lombroso P. Genetics of Childhood Disorders: XXXII. Autoimmune Disorders, Part 5: Streptococcal Infection and Autoimmunity, an Epidemiological Perspective. Journal Of The American Academy Of Child & Adolescent Psychiatry 2001, 40: 1346-1348. PMID: 11699810, DOI: 10.1097/00004583-200111000-00016.Peer-Reviewed Original ResearchAntibodies against neural, nuclear, cytoskeletal, and streptococcal epitopes in children and adults with Tourette’s syndrome, Sydenham’s chorea, and autoimmune disorders
Morshed S, Parveen S, Leckman J, Mercadante M, Kiss M, Miguel E, Arman A, Yazgan Y, Fujii T, Paul S, Peterson B, Zhang H, King R, Scahill L, Lombroso P. Antibodies against neural, nuclear, cytoskeletal, and streptococcal epitopes in children and adults with Tourette’s syndrome, Sydenham’s chorea, and autoimmune disorders. Biological Psychiatry 2001, 50: 566-577. PMID: 11690591, DOI: 10.1016/s0006-3223(01)01096-4.Peer-Reviewed Original ResearchConceptsTotal antinuclear antibodiesAntinuclear antibodiesAutoimmune disordersTourette syndromeAnticytoskeletal antibodiesAntineural antibodiesStreptococcal infectionT patientsTS patientsBeta-hemolytic streptococcal infectionPrior streptococcal infectionHemolytic streptococcal infectionAntistreptolysin O titerIndirect immunofluorescent assayLevels of immunoreactivityWestern blot techniqueMean rankClinical characteristicsSydenham's choreaO titerPatient groupSC patientsIgG antibodiesIgG classNormal controlsThermal Sensitivity in Tourette Syndrome: Preliminary Report
Scahill L, Lombroso P, Mack G, Van Wattum P, Zhang H, Vitale A, Leckman J. Thermal Sensitivity in Tourette Syndrome: Preliminary Report. Perceptual And Motor Skills 2001, 92: 419-432. PMID: 11361302, DOI: 10.2466/pms.2001.92.2.419.Peer-Reviewed Original ResearchMeSH KeywordsAdultBody Temperature RegulationFemaleHumansMalePrevalenceSeverity of Illness IndexTicsTime FactorsTourette SyndromeConceptsTourette syndromeSubgroup of patientsAge of onsetAdult male subjectsCurrent ageTic symptomsDopaminergic pathwaysSex distributionCurrent severityMale subjectsMean differenceSyndromeControl periodPreliminary reportSweat rateAgeSymptomsSubjectsOverall courseDegrees COnsetPatientsIllnessSeverityCourseGroup A streptococcal infections and their potential role in neuropsychiatric disease.
Bessen D, Lombroso P. Group A streptococcal infections and their potential role in neuropsychiatric disease. Advances In Neurology 2001, 85: 295-305. PMID: 11530436.Peer-Reviewed Original Research
1999
DEVELOPMENT AND NEUROBIOLOGY: Genetics of Childhood Disorders V. Nonparametric Methods of Genetic Analysis
LOMBROSO P, KOHN Y, LOMBROSO P. DEVELOPMENT AND NEUROBIOLOGY: Genetics of Childhood Disorders V. Nonparametric Methods of Genetic Analysis. Journal Of The American Academy Of Child & Adolescent Psychiatry 1999, 38: 1054-1056. PMID: 10434500, DOI: 10.1097/00004583-199908000-00024.Peer-Reviewed Original ResearchMeSH KeywordsAllelesChildChromosome MappingGenetic MarkersHumansMental DisordersPedigreeStatistics, NonparametricTourette Syndrome
1995
Risperidone Treatment of Children and Adolescents with Chronic Tic Disorders: A Preliminary Report
LOMBROSO P, SCAHILL L, KING R, LYNCH K, CHAPPELL P, PETERSON B, McDOUGLE C, LECKMAN J. Risperidone Treatment of Children and Adolescents with Chronic Tic Disorders: A Preliminary Report. Journal Of The American Academy Of Child & Adolescent Psychiatry 1995, 34: 1147-1152. PMID: 7559308, DOI: 10.1097/00004583-199509000-00011.Peer-Reviewed Original ResearchConceptsChronic tic disorderTic disordersObsessive-compulsive disorderChronic motor tic disorderYale Global Tic Severity ScaleDopamine-blocking propertiesOpen-label trialFrequent side effectsEfficacy of risperidoneMotor tic disorderShort-term safetyTic Severity ScaleComorbid obsessive-compulsive disorderYale-Brown Obsessive Compulsive ScaleObsessive Compulsive ScaleClinical responseRisperidone treatmentMean ageTic scoreSeverity ScaleSide effectsTourette syndromeComorbid diagnosesTic frequencyWeight gain
1994
Genetic Mechanisms in Childhood Psychiatric Disorders
LOMBROSO P, PAULS D, LECKMAN J. Genetic Mechanisms in Childhood Psychiatric Disorders. Journal Of The American Academy Of Child & Adolescent Psychiatry 1994, 33: 921-938. PMID: 7525534, DOI: 10.1097/00004583-199409000-00001.Peer-Reviewed Original ResearchMeSH KeywordsAdoptionAttention Deficit Disorder with HyperactivityAutistic DisorderChildChild, PreschoolChromosome AberrationsChromosome DisordersDevelopmental DisabilitiesDiseases in TwinsEnvironmentFamilyGenetic LinkageHumansInfantInfant, NewbornKaryotypingMood DisordersRNA, MessengerTourette SyndromeConceptsMolecular basisGenetic researchChildhood psychiatric disordersGenetic mechanismsPsychiatric disordersGenetic factorsMolecular understandingComplex behavioral disordersChildhood disordersGenetic etiologyCertain childhood disordersCertain developmental disordersDevelopmental disordersPsychiatric illness