Featured Publications
Pharmacological and behavioral treatment for trichotillomania: An updated systematic review with meta‐analysis
Farhat LC, Olfson E, Nasir M, Levine JLS, Li F, Miguel EC, Bloch MH. Pharmacological and behavioral treatment for trichotillomania: An updated systematic review with meta‐analysis. Depression And Anxiety 2020, 37: 715-727. PMID: 32390221, DOI: 10.1002/da.23028.Peer-Reviewed Original ResearchMeSH KeywordsAcetylcysteineBehavior TherapyClomipramineHumansSelective Serotonin Reuptake InhibitorsTrichotillomaniaConceptsClinical trialsSingle randomized clinical trialTTM symptomsFirst-line medicationRandomized clinical trialsStrong evidence baseLarge treatment effectsHair pulling disorderEffective medicationsAvailable agentsPharmacological agentsAdditional trialsDrug AdministrationPsychiatric conditionsSystematic reviewN-acetylcysteineBehavioral treatmentBehavioral therapyEvidence baseTrichotillomaniaTrialsRelative efficacyTreatment effectsMedicationsSymptoms
2019
The Potential of Cannabinoid-Based Treatments in Tourette Syndrome
Artukoglu BB, Bloch MH. The Potential of Cannabinoid-Based Treatments in Tourette Syndrome. CNS Drugs 2019, 33: 417-430. PMID: 30977108, DOI: 10.1007/s40263-019-00627-1.Peer-Reviewed Original ResearchConceptsTourette syndromeCannabinoid systemAdult populationPositive urine drug screenBiological rationaleCannabinoid-based treatmentsPotential of cannabinoidsTourette syndrome populationsPlacebo-controlled trialTreatment of ticsUrine drug screensNovel pharmacological treatmentsCannabis-derived compoundsStrong biological rationaleCurrent evidence baseComprehensive literature searchDevelopmental adverse effectsRefractory patientsSafety profilePharmacological treatmentClinical trialsTic disordersUncertain efficacyFurther trialsSyndrome population
2016
Systematic Review of Pharmacological and Behavioral Treatments for Skin Picking Disorder
Schumer MC, Bartley CA, Bloch MH. Systematic Review of Pharmacological and Behavioral Treatments for Skin Picking Disorder. Journal Of Clinical Psychopharmacology 2016, 36: 147-152. PMID: 26872117, PMCID: PMC4930073, DOI: 10.1097/jcp.0000000000000462.Peer-Reviewed Original ResearchConceptsInactive control conditionsUncontrolled trialsBehavioral treatmentSystematic reviewLarger placebo-controlled RCTsSelective serotonin reuptake inhibitorsShort-term clinical trialsBehavioral interventionsPlacebo-controlled RCTsSerotonin reuptake inhibitorsSkin picking disorderEfficacy of treatmentNovel pharmacological agentsShort-term trialsReuptake inhibitorsTreatment armsControl conditionClinical trialsDemonstrated efficacyPsychiatric disordersPharmacological agentsSignificant improvementElectronic databasesRCTsMeta-Analysis
2015
LONG‐TERM OUTCOME IN PEDIATRIC TRICHOTILLOMANIA
Schumer MC, Panza KE, Mulqueen JM, Jakubovski E, Bloch MH. LONG‐TERM OUTCOME IN PEDIATRIC TRICHOTILLOMANIA. Depression And Anxiety 2015, 32: 737-743. PMID: 26139231, PMCID: PMC4591183, DOI: 10.1002/da.22390.Peer-Reviewed Original ResearchConceptsPoor long-term prognosisLong-term prognosisLong-term outcomesN-acetylcysteineDepressive symptomsPediatric trichotillomaniaTrichotillomania symptomsOlder ageAdequate symptom reliefPlacebo-controlled trialAnxiety symptomsPredictors of outcomePrevious cross-sectional studiesRisk of depressionCross-sectional studyPrimary outcomeSymptom reliefAcute phaseClinical assessmentTreatment utilizationBaseline evaluationSecondary measuresBaseline assessmentSymptomsBehavioral treatment
2014
Meta-analysis: hoarding symptoms associated with poor treatment outcome in obsessive–compulsive disorder
Bloch MH, Bartley CA, Zipperer L, Jakubovski E, Landeros-Weisenberger A, Pittenger C, Leckman JF. Meta-analysis: hoarding symptoms associated with poor treatment outcome in obsessive–compulsive disorder. Molecular Psychiatry 2014, 19: 1025-1030. PMID: 24912494, PMCID: PMC4169729, DOI: 10.1038/mp.2014.50.Peer-Reviewed Original ResearchMeSH KeywordsAdultBehavior TherapyChildHoarding DisorderHumansPsychotropic DrugsRandomized Controlled Trials as TopicTreatment OutcomeConceptsObsessive-compulsive disorderTreatment responseOCD patientsOdds ratioFurther treatment researchCase-control studyPoor treatment outcomesDifferential treatment responseSymptoms of OCDPrimary outcomeTreatment modalitiesEligible studiesTreatment outcomesPatientsElectronic searchSymptomsTotal participantsBehavioral therapyOCD treatmentDisordersSymptom dimensionsTreatment researchDSM-5Hoarding symptomsTreatment
2013
Meta-Analysis
Mulqueen JM, Bartley CA, Bloch MH. Meta-Analysis. Journal Of Attention Disorders 2013, 19: 118-124. PMID: 24071773, DOI: 10.1177/1087054713504135.Peer-Reviewed Original ResearchMeSH KeywordsAttention Deficit Disorder with HyperactivityBehavior TherapyChildChild, PreschoolHumansMaleParentingParentsTreatment OutcomeConceptsMedication managementBehavioral interventionsPrimary outcome measureTreatment of ADHDControl conditionCochrane LibraryADHD Rating ScaleOutcome measuresMean improvementEfficacious treatmentSide effectsMeta-AnalysisParental interventionRating ScaleFinal analysisRelative efficacyInterventionYoung childrenPreliminary evidenceParent interventionPreschool childrenTrialsEfficacyADHDParental preferences
2012
D-cycloserine augmentation of behavioral therapy for the treatment of anxiety disorders: a meta-analysis.
Bontempo A, Panza KE, Bloch MH. D-cycloserine augmentation of behavioral therapy for the treatment of anxiety disorders: a meta-analysis. The Journal Of Clinical Psychiatry 2012, 73: 533-7. PMID: 22579153, PMCID: PMC3625928, DOI: 10.4088/jcp.11r07356.Peer-Reviewed Original Research
2009
Trichotillomania Across the Life Span
Kratochvil C, Bloch M. Trichotillomania Across the Life Span. Journal Of The American Academy Of Child & Adolescent Psychiatry 2009, 48: 879-883. PMID: 19692854, DOI: 10.1097/chi.0b013e3181ae09f3.Peer-Reviewed Original ResearchAcetylcysteineAdolescentAdultAge FactorsAntipsychotic AgentsBehavior TherapyChildChild, PreschoolCommunity Mental Health ServicesExcitatory Amino Acid AgentsHumansNaltrexoneNarcotic AntagonistsRandomized Controlled Trials as TopicSelective Serotonin Reuptake InhibitorsTreatment OutcomeTrichotillomania
2007
Systematic Review: Pharmacological and Behavioral Treatment for Trichotillomania
Bloch MH, Landeros-Weisenberger A, Dombrowski P, Kelmendi B, Wegner R, Nudel J, Pittenger C, Leckman JF, Coric V. Systematic Review: Pharmacological and Behavioral Treatment for Trichotillomania. Biological Psychiatry 2007, 62: 839-846. PMID: 17727824, DOI: 10.1016/j.biopsych.2007.05.019.Peer-Reviewed Original ResearchConceptsSelective serotonin reuptake inhibitorsHabit reversal therapyTreatment of trichotillomaniaCochrane Central RegisterPrimary outcome measureClinical rating scalesNon-specific effectsSSRI pharmacotherapyCentral RegisterControlled TrialsRelevant trialsReuptake inhibitorsTreat analysisPharmacotherapy studiesBlinded assessmentClinical trialsTrichotillomania severityMean changeOutcome measuresFuture therapiesElectronic databasesLarger sample sizeRigorous control conditionsPsychiatric conditionsSystematic review