2020
Meta-analysis: Pharmacologic Treatment of Restricted and Repetitive Behaviors in Autism Spectrum Disorders
Zhou MS, Nasir M, Farhat LC, Kook M, Artukoglu BB, Bloch MH. Meta-analysis: Pharmacologic Treatment of Restricted and Repetitive Behaviors in Autism Spectrum Disorders. Journal Of The American Academy Of Child & Adolescent Psychiatry 2020, 60: 35-45. PMID: 32387445, DOI: 10.1016/j.jaac.2020.03.007.Peer-Reviewed Original ResearchConceptsSelective serotonin reuptake inhibitorsPlacebo-controlled trialPharmacological treatmentPharmacological agentsAvailable pharmacological agentsAutism spectrum disorderSerotonin reuptake inhibitorsStandardized mean differenceStandardized study designsTreatment of ASDPharmacologic treatmentPrimary outcomeReuptake inhibitorsAntipsychotic medicationSpecific assessment toolsFolinic acidSpectrum disorderModest benefitRepetitive behaviorsMean differenceStudy designSmall effect sizesIndividual studiesTrialsPlacebo
2017
Antipsychotics for aggression in adults: A meta-analysis
van Schalkwyk GI, Beyer C, Johnson J, Deal M, Bloch MH. Antipsychotics for aggression in adults: A meta-analysis. Progress In Neuro-Psychopharmacology And Biological Psychiatry 2017, 81: 452-458. PMID: 28754408, DOI: 10.1016/j.pnpbp.2017.07.019.Peer-Reviewed Original ResearchConceptsTreatment of aggressionAntipsychotic medicationNon-pharmacologic interventionsEffect sizeChoice of agentSignificant dose effectSignificant morbidityCochrane LibraryAntipsychotic agentsDopamine antagonistsPsychiatric illnessIrritable moodMultiple diagnosesClinical decisionAntipsychoticsSpecific agentsSearch termsSmall effect sizesDiagnosisDose effectMedicationsSymptom dimensionsAggressive behaviorTreatmentAdults