2020
What Is the Difference in Cranial Base Morphology in Isolated and Syndromic Bicoronal Synostosis?
Lu X, Forte AJ, Wilson AT, Park KE, Allam O, Mozaffari MA, Alperovich M, Steinbacher DM, Alonso N, Persing JA. What Is the Difference in Cranial Base Morphology in Isolated and Syndromic Bicoronal Synostosis? Plastic & Reconstructive Surgery 2020, 146: 599-610. PMID: 32842109, DOI: 10.1097/prs.0000000000007068.Peer-Reviewed Original ResearchSphenoid Bone Structure and Its Influence on the Cranium in Syndromic Versus Nonsyndromic Craniosynostosis.
Lu X, Forte AJ, Park KE, Allam O, Mozaffari MA, Alperovich M, Steinbacher DM, Alonso N, Persing JA. Sphenoid Bone Structure and Its Influence on the Cranium in Syndromic Versus Nonsyndromic Craniosynostosis. Journal Of Craniofacial Surgery 2020, 32: 67-72. PMID: 32868725, DOI: 10.1097/scs.0000000000006914.Peer-Reviewed Original ResearchCranial Fossa Development in Differing Subtypes of Crouzon Syndrome.
Lu X, Forte AJ, Steinbacher DM, Alperovich M, Alonso N, Persing JA. Cranial Fossa Development in Differing Subtypes of Crouzon Syndrome. Journal Of Craniofacial Surgery 2020, 31: 673-677. PMID: 32049910, DOI: 10.1097/scs.0000000000006181.Peer-Reviewed Original ResearchCranial Fossa, PosteriorCraniofacial DysostosisCraniosynostosesFemaleHumansMaleTomography, X-Ray ComputedClassification of Subtypes of Crouzon Syndrome Based on the Type of Vault Suture Synostosis.
Lu X, Sawh-Martinez R, Forte AJ, Wu R, Cabrejo R, Wilson A, Steinbacher DM, Alperovich M, Alonso N, Persing JA. Classification of Subtypes of Crouzon Syndrome Based on the Type of Vault Suture Synostosis. Journal Of Craniofacial Surgery 2020, 31: 678-684. PMID: 32068731, DOI: 10.1097/scs.0000000000006173.Peer-Reviewed Original ResearchConceptsClass IIICrouzon syndromeClass IClass IISuture involvementSuture synostosisSimilar craniofacial characteristicsComputed tomography scanClassification of subtypesSurgical interventionMorphology of patientsAnatomic deformityTomography scanSurgical techniqueCT scanDifferent subtypesSagittal synostosisSyndromeClass IVPremature closureCraniofacial characteristicsSevere craniofacial malformationsCranial base lengthSynostosisDifferent pathologiesRacial disparity of Crouzon syndrome in maxilla and mandible
Lu X, Forte AJ, Fan F, Zhang Z, Teng L, Yang B, Alperovich M, Steinbacher DM, Alonso N, Persing JA. Racial disparity of Crouzon syndrome in maxilla and mandible. International Journal Of Oral And Maxillofacial Surgery 2020, 49: 1566-1575. PMID: 32362538, DOI: 10.1016/j.ijom.2020.04.005.Peer-Reviewed Original ResearchMeSH KeywordsCephalometryCraniofacial DysostosisHumansMalocclusion, Angle Class IIIMandibleMaxillaPrognathismConceptsAsian patientsCaucasian patientsCrouzon syndrome patientsCrouzon syndromeSyndrome patientsRacial disparitiesAnteroposterior maxillary lengthMidface profileTomography scanPatientsMandibular volumeCaucasian controlsCraniosynostosis patientsMaxillary positioningMaxillary lengthSyndromeVolume deficiencyANB angleAsian controlsMandibular lengthBackward displacementMaterialise softwareMaxillaSame extentMaxilla length
2019
What Is the Skull Structure Influence of Squamosal Suture Synostosis in Nonsyndromic and Syndromic Crouzon Craniosynostosis?
Lu X, Chen G, Forte AJ, Cabrejo R, Singh A, Kyle G, Steinbacher DM, Alperovich M, Alonso N, Persing JA. What Is the Skull Structure Influence of Squamosal Suture Synostosis in Nonsyndromic and Syndromic Crouzon Craniosynostosis? Journal Of Craniofacial Surgery 2019, 30: 1671-1675. PMID: 30950948, DOI: 10.1097/scs.0000000000005396.Peer-Reviewed Original ResearchMeSH KeywordsCephalometryChildChild, PreschoolCranial SuturesCraniofacial DysostosisCraniosynostosesFemaleHumansMalePlastic Surgery ProceduresSkullTomography, X-Ray ComputedConceptsMiddle cranial fossaAnterior cranial fossaCranial fossaPosterior cranial fossaSquamosal synostosisFossa volumeCrouzon syndromeSquamosal suture synostosisComputed tomography scanCranial volumeNonsyndromic craniosynostosis patientsVolume reductionSevere volume reductionTomography scanNormal controlsMorphologic effectsCraniosynostosis patientsFossaPremature closureSyndromic conditionsSuture synostosisSyndromic synostosisFrankfort horizontal planeSynostosisThree-dimensional cephalometryEnlarged anterior cranial fossa and restricted posterior cranial fossa, the disproportionate growth of basicranium in Crouzon syndrome
Lu X, Forte AJ, Steinbacher DM, Alperovich M, Alonso N, Persing JA. Enlarged anterior cranial fossa and restricted posterior cranial fossa, the disproportionate growth of basicranium in Crouzon syndrome. Journal Of Cranio-Maxillofacial Surgery 2019, 47: 1426-1435. PMID: 31331854, DOI: 10.1016/j.jcms.2019.06.003.Peer-Reviewed Original ResearchMeSH KeywordsCranial Fossa, AnteriorCranial Fossa, MiddleCranial Fossa, PosteriorCraniofacial DysostosisHumansSkull BaseConceptsPosterior cranial fossa volumePosterior cranial fossaCranial fossaFossa volumeCrouzon syndrome patientsCrouzon syndromeSyndrome patientsCT scanSegmental anteriorSurgical treatment planPreoperative CT scanAnterior cranial fossaMonths of ageMiddle cranial fossaPosterior cranial expansionNormal intracranial volumeIntracranial volume measurementsTreatment planIntracranial volumePatientsFossaSyndromeCranial expansionCranial volumeAnteriorAssociation of Regional Cranial Base Deformity and Ultimate Structure in Crouzon Syndrome.
Lu X, Jorge Forte A, Sawh-Martinez R, Wu R, Cabrejo R, Steinbacher DM, Alperovich M, Alonso N, Persing JA. Association of Regional Cranial Base Deformity and Ultimate Structure in Crouzon Syndrome. Plastic & Reconstructive Surgery 2019, 143: 1233e-1243e. PMID: 31136487, DOI: 10.1097/prs.0000000000005643.Peer-Reviewed Original ResearchAnalysis of Airway and Midface in Crouzon Syndromes
Forte AJ, Lu X, Hashim PW, Steinbacher DM, Alperovich M, Persing JA, Alonso N. Analysis of Airway and Midface in Crouzon Syndromes. Annals Of Plastic Surgery 2019, Publish Ahead of Print: &na;. PMID: 30633021, DOI: 10.1097/sap.0000000000001740.Peer-Reviewed Original ResearchConceptsPharyngeal airway volumeComputed tomography scanAirway volumeControl subjectsTomography scanCrouzon syndromeAge-matched control subjectsAnalysis of airwaysSevere respiratory impairmentNasal airway volumePosterior pharyngeal wallEarly mixed dentitionCrouzon groupSurgical interventionRespiratory impairmentUpper airwaySoft tissue measurementsPharyngeal wallPosterior tongueMixed dentitionAirwayPatientsSyndromeVolumetric assessmentT-testMandibular Spatial Reorientation and Morphological Alteration of Crouzon and Apert Syndrome.
Lu X, Sawh-Martinez R, Forte AJ, Wu R, Cabrejo R, Wilson A, Steinbacher DM, Alperovich M, Alonso N, Persing JA. Mandibular Spatial Reorientation and Morphological Alteration of Crouzon and Apert Syndrome. Annals Of Plastic Surgery 2019, 83: 568-582. PMID: 31008788, DOI: 10.1097/sap.0000000000001811.Peer-Reviewed Original Research
2018
Orbit, zygoma, and maxilla growth patterns in Crouzon syndrome
Lu X, Forte AJ, Sawh-Martinez R, Wu R, Cabrejo R, Steinbacher DM, Alperovich M, Alonso N, Persing JA. Orbit, zygoma, and maxilla growth patterns in Crouzon syndrome. International Journal Of Oral And Maxillofacial Surgery 2018, 48: 309-321. PMID: 30389113, DOI: 10.1016/j.ijom.2018.10.013.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAnthropometryChildChild, PreschoolCraniofacial DysostosisFemaleHumansInfantInfant, NewbornMaleMaxillaMiddle AgedOrbitTomography, X-Ray ComputedZygomaConceptsCrouzon syndromeCT scanAnteroposterior lengthWidth of maxillaPreoperative CT scanMonths-2 yearsMonths of agePrincipal deformityControl subjectsGlobe projectionAge subgroupsMaxillary wideningSecondary deformitiesOrbital wallAnterior protrusionSyndromeFacial malformationsMonthsDeformityAnteroposterior positionZygomatic regionCranial baseZygomaMalformationsMaterialise software
2017
Minor Suture Fusion in Syndromic Craniosynostosis
Runyan CM, Xu M D W, Alperovich M, Massie M D J, Paek G, Cohen BA, Staffenberg DA, Flores RL, Taylor JA. Minor Suture Fusion in Syndromic Craniosynostosis. Plastic & Reconstructive Surgery 2017, 140: 434e-445e. PMID: 28574949, DOI: 10.1097/prs.0000000000003586.Peer-Reviewed Original ResearchMeSH KeywordsCranial SuturesCraniofacial DysostosisCraniosynostosesFemaleHumansInfantIntracranial PressureMaleReceptor, Fibroblast Growth Factor, Type 2Tomography, X-Ray ComputedConceptsSuture synostosisCLINICAL QUESTION/LEVELSyndromic craniosynostosisSuture fusionMost patientsTomographic scanSyndromic patientsPatientsPosterior branchSkull baseCraniofacial dysostosisHead shape anomaliesSuture involvementInfantsFGFR2 mutationsSynostosisMidface abnormalitiesCraniofacial surgeonsCraniosynostosisCraniofacial dysostosis syndromesSelect groupCalvarial suturesScansShape anomaliesPatent calvarial sutures