2022
To what extent do social support and mastery mediate the association between childhood maltreatment and depression? A sequential causal mediation analysis
Su Y, Li M, D'Arcy C, Caron J, O'Donnell K, Meng X. To what extent do social support and mastery mediate the association between childhood maltreatment and depression? A sequential causal mediation analysis. Epidemiology And Psychiatric Sciences 2022, 31: e77. PMID: 36263598, PMCID: PMC9677445, DOI: 10.1017/s2045796022000609.Peer-Reviewed Original ResearchConceptsMajor depressionLongitudinal population-based studySocial supportPopulation-based studyDevelopment of depressionSequential causal mediation analysisMaltreatment subtypesChildhood maltreatment subtypesPsychosocial attributesPotential confoundingSubsequent depressionSubtypesCausal mediation analysisDepressionScientific evidenceChildhood maltreatmentVicious cycleIndependent roleAssociationDirect effectMediation analysisStudied variablesMajor contributorMaltreatmentSpecific and cumulative lifetime stressors in the aetiology of major depression: A longitudinal community-based population study
Su Y, D'Arcy C, Li M, O'Donnell K, Caron J, Meaney M, Meng X. Specific and cumulative lifetime stressors in the aetiology of major depression: A longitudinal community-based population study. Epidemiology And Psychiatric Sciences 2022, 31: e3. PMID: 35078547, PMCID: PMC8851045, DOI: 10.1017/s2045796021000779.Peer-Reviewed Original ResearchConceptsGenetic predispositionSubsequent depressionStressful life eventsLifetime stressorsLongitudinal community-based cohort studyPsychosocial stressorsCommunity-based cohort studyCommunity-based population studyStressful eventsMental illness preventionMultivariate logistic regressionHealth-related factorsDevelopment of depressionChildhood maltreatmentMental health promotionEtiology of depressionPresent studyStressful experiencesLife eventsChild-parent bondingCumulative stressful experiencesSouthwest of MontrealPolygenetic risk scoresCohort studySocio-demographic characteristics
2014
Cortisol awakening response and subsequent depression: prospective longitudinal study
Carnegie R, Araya R, Ben-Shlomo Y, Glover V, O'Connor TG, O'Donnell KJ, Pearson R, Lewis G. Cortisol awakening response and subsequent depression: prospective longitudinal study. The British Journal Of Psychiatry 2014, 204: 137-143. PMID: 24311550, PMCID: PMC3909839, DOI: 10.1192/bjp.bp.113.126250.Peer-Reviewed Original ResearchConceptsCortisol awakening responseSubsequent depressionSalivary cortisolAwakening responseOdds ratioTime pointsICD-10 criteriaLongitudinal studyProspective longitudinal studyAvon Longitudinal StudyShort-term riskSubsequent depressive illnessLarge population cohortAdrenal functionDepressive illnessClinical significancePopulation cohortElevated cortisolCortisolLogistic regressionCortisol measuresStress reactivityDepressionDiurnal dropAssociation