2019
Dynamic DNA methylation changes in the maternal oxytocin gene locus (OXT) during pregnancy predict postpartum maternal intrusiveness
Toepfer P, O'Donnell KJ, Entringer S, Garg E, Heim CM, Lin DTS, MacIsaac JL, Kobor MS, Meaney MJ, Provençal N, Binder EB, Wadhwa PD, Buss C. Dynamic DNA methylation changes in the maternal oxytocin gene locus (OXT) during pregnancy predict postpartum maternal intrusiveness. Psychoneuroendocrinology 2019, 103: 156-162. PMID: 30690225, PMCID: PMC6554513, DOI: 10.1016/j.psyneuen.2019.01.013.Peer-Reviewed Original ResearchConceptsLate pregnancyMaternal behaviorMonths postpartumEarly postnatal developmentNovel potential biomarkersRace/ethnicityPregnancy inducesPeripheral bloodPregnancyMother-child dyadsPostnatal maternal behaviourPostnatal developmentPotential biomarkersSteroid hormonesDNA methylationSocioeconomic statusWhole bloodPromoter DNA methylationMother-child interactionPostpartumBloodDNA methylation changesOxytocinDNAm trajectoriesMaternal intrusiveness
2012
Prenatal versus postnatal sex steroid hormone effects on autistic traits in children at 18 to 24 months of age
Auyeung B, Ahluwalia J, Thomson L, Taylor K, Hackett G, O’Donnell K, Baron-Cohen S. Prenatal versus postnatal sex steroid hormone effects on autistic traits in children at 18 to 24 months of age. Molecular Autism 2012, 3: 17. PMID: 23231861, PMCID: PMC3554559, DOI: 10.1186/2040-2392-3-17.Peer-Reviewed Original ResearchMonths of ageAndrogen exposureSex steroid hormone effectsFT levelsSex steroid hormone levelsSex steroid hormonesSteroid hormone levelsSecond trimester amniocentesisSteroid hormone effectsMonths old toddlersPostnatal androgen exposurePrenatal androgen exposureConclusionsThese preliminary findingsEstradiol levelsPostnatal exposurePregnant womenPrenatal exposureHormone levelsPostnatal testosterone levelsTestosterone levelsAndrogen hormonesAmniotic fluidLarger sample populationHormone effectsSteroid hormones