2022
Maternal Prenatal Infection and Anxiety Predict Neurodevelopmental Outcomes in Middle Childhood
O’Connor T, Ciesla AA, Sefair AV, Thornburg LL, Brown AS, Glover V, O’Donnell K. Maternal Prenatal Infection and Anxiety Predict Neurodevelopmental Outcomes in Middle Childhood. Journal Of Psychopathology And Clinical Science 2022, 131: 422-434. PMID: 35238594, PMCID: PMC9069845, DOI: 10.1037/abn0000746.Peer-Reviewed Original ResearchConceptsChild neurodevelopmentSelf-report questionnairesPrenatal maternal anxietyPrediction of symptomsAttention problemsMiddle childhoodCommunication problemsAnxiety symptomsPerson testingAvon Longitudinal StudyEmotional symptomsPrenatal anxietyPrenatal riskPrenatal maternal infectionMaternal anxietyAnxietyMental healthLongitudinal studyPrenatal infectionSeparate linesLine of studyLarge prospective longitudinal cohort studyProspective longitudinal cohort studyChild CohortNeurodevelopment
2021
Maternal Prenatal Anxiety and the Fetal Origins of Epigenetic Aging
McGill MG, Pokhvisneva I, Clappison AS, McEwen LM, Beijers R, Tollenaar MS, Pham H, Kee MZL, Garg E, de Mendonça Filho EJ, Karnani N, Silveira PP, Kobor MS, de Weerth C, Meaney MJ, O'Donnell KJ. Maternal Prenatal Anxiety and the Fetal Origins of Epigenetic Aging. Biological Psychiatry 2021, 91: 303-312. PMID: 34756561, DOI: 10.1016/j.biopsych.2021.07.025.Peer-Reviewed Original ResearchConceptsPrenatal maternal anxietyFetal originEpigenetic age accelerationMaternal anxietyAge accelerationPrenatal anxietyMental healthPrenatal maternal mental healthMaternal mental healthYears of ageGenetic risk factorsMonths of ageMental health supportMaternal prenatal anxietyRisk factorsLongitudinal cohortPrenatal adversityPregnant individualsLarge effect sizesLongitudinal assessmentHealth supportEffective mental health supportCohortPrenatal environmentLate childhood
2014
Maternal prenatal anxiety and child brain-derived neurotrophic factor (BDNF) genotype: Effects on internalizing symptoms from 4 to 15 years of age
O'Donnell KJ, Glover V, Holbrook JD, O'Connor TG. Maternal prenatal anxiety and child brain-derived neurotrophic factor (BDNF) genotype: Effects on internalizing symptoms from 4 to 15 years of age. Development And Psychopathology 2014, 26: 1255-1266. PMID: 25422959, DOI: 10.1017/s095457941400100x.Peer-Reviewed Original ResearchConceptsBrain-derived neurotrophic factor (BDNF) genePrenatal maternal anxietyYears of agePrenatal anxietyBDNF polymorphismMaternal anxietyBrain-derived neurotrophic factor (BDNF) genotypeNeurotrophic factor genotypeInternalizing symptomsNeurotrophic factor geneAge 15 yearsAvon Longitudinal StudyMaternal prenatal anxietyMaternal symptomsChild internalizing symptomsGene-environment interactionsClinical InterviewPopulation cohortHealth outcomesSymptomsDiagnostic assessmentPsychosocial risksDifficulties QuestionnaireAge 13Longitudinal study
2013
Stressful events and psychological difficulties: testing alternative candidates for sensitivity
Laceulle OM, O’Donnell K, Glover V, O’Connor T, Ormel J, van Aken MA, Nederhof E. Stressful events and psychological difficulties: testing alternative candidates for sensitivity. European Child & Adolescent Psychiatry 2013, 23: 103-113. PMID: 23756816, DOI: 10.1007/s00787-013-0436-4.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAffective SymptomsAnxiety DisordersChildChild DevelopmentChild of Impaired ParentsChild, PreschoolDisease SusceptibilityFemaleHumansLife Change EventsMaleMothersPregnancyPrenatal Exposure Delayed EffectsProspective StudiesRisk FactorsSex FactorsSocial EnvironmentSocioeconomic FactorsStress, PsychologicalSurveys and QuestionnairesTime FactorsConceptsPsychological difficultiesStressful eventsDifficult temperamentPrenatal anxietyLife eventsSources of sensitivityStressful life eventsPrenatal maternal anxietyChild developmentReciprocal associationsAge 7Maternal anxietyAge 4Child's ageTemperamentLongitudinal studyStress exposureAnxietyEarly childhoodCurrent studyConsistent evidenceChildrenPrior workDifficultiesAdditional research