2022
Polygenic risk score and peer victimisation independently predict depressive symptoms in adolescence: results from the Quebec Longitudinal Study of Children Development
Perret LC, Boivin M, Morneau‐Vaillancourt G, Andlauer TFM, Paquin S, Langevin S, Girard A, Turecki G, O'Donnell K, Tremblay RE, Côté SM, Gouin J, Ouellet‐Morin I, Geoffroy M. Polygenic risk score and peer victimisation independently predict depressive symptoms in adolescence: results from the Quebec Longitudinal Study of Children Development. Journal Of Child Psychology And Psychiatry 2022, 64: 388-396. PMID: 36124742, DOI: 10.1111/jcpp.13706.Peer-Reviewed Original ResearchConceptsDepressive symptomsGenetic predispositionQuebec Longitudinal StudyPolygenic risk scoresRisk scoreSelf-reported depressive symptomsLongitudinal studyIndividual genetic predispositionSuch gene-environment interactionsGene-environment interactionsSuch symptomsSymptomsDepressionChild developmentPredispositionAdolescencePeer victimisationFuture studiesEarly adolescenceScoresRiskAdolescentsAssociation
2014
Early life adversity and the epigenetic programming of hypothalamic-pituitary-adrenal function
Anacker C, O'Donnell KJ, Meaney MJ. Early life adversity and the epigenetic programming of hypothalamic-pituitary-adrenal function. Dialogues In Clinical Neuroscience 2014, 16: 321-333. PMID: 25364283, PMCID: PMC4214175, DOI: 10.31887/dcns.2014.16.3/canacker.Peer-Reviewed Original ResearchConceptsExpression of genesParent-offspring interactionsEpigenetic stateEpigenetic mechanismsEpigenetic programmingEpigenetic studiesStress responseGenesNonhuman speciesAdrenal functionExpressionSpeciesEarly life adversityEarly childhood adversityLater riskFuture studiesChildhood adversityLife adversityFunctionSocial adversityAlters