2013
Maternal prenatal symptoms of depression and down regulation of placental monoamine oxidase A expression
Blakeley PM, Capron LE, Jensen AB, O'Donnell KJ, Glover V. Maternal prenatal symptoms of depression and down regulation of placental monoamine oxidase A expression. Journal Of Psychosomatic Research 2013, 75: 341-345. PMID: 24119940, DOI: 10.1016/j.jpsychores.2013.07.002.Peer-Reviewed Original ResearchConceptsPlacental functionPrenatal symptomsA ExpressionSymptoms of depressionMaternal trait anxietyPlacental monoamine oxidaseElective caesareanNeurodevelopmental outcomesFetal exposureMAO AMaternal symptomsPregnant womenMaternal moodMonoamine oxidase APlacental expressionMaternal depressionFetal bloodSymptomsTrophoblast tissueMonoamine oxidaseSpecific polyclonal antibodiesDepressionOxidase APsychometric testsPlacenta
2011
Maternal prenatal anxiety and downregulation of placental 11β-HSD2
O’Donnell K, Jensen A, Freeman L, Khalife N, O’Connor T, Glover V. Maternal prenatal anxiety and downregulation of placental 11β-HSD2. Psychoneuroendocrinology 2011, 37: 818-826. PMID: 22001010, DOI: 10.1016/j.psyneuen.2011.09.014.Peer-Reviewed Original ResearchConceptsPlacental 11β-HSD2Maternal prenatal anxietyMaternal anxietyPlacental 11β-hydroxysteroid dehydrogenase type 2Prenatal stressPrenatal anxietyDepression self-rating scalePrenatal maternal moodAdverse neurodevelopmental outcomesDehydrogenase type 2Subset of casesElective caesareanNeurodevelopmental outcomesFetal exposureMaternal moodMaternal cortisolFetal programmingState anxietyAnimal studiesSelf-rating scaleFemale fetusesType 2MRNA expressionDownregulationCortisol