Interplay between uncertainty intolerance, emotion regulation, cognitive flexibility, and psychopathology during the COVID-19 pandemic: a multi-wave study
Godara M, Everaert J, Sanchez-Lopez A, Joormann J, De Raedt R. Interplay between uncertainty intolerance, emotion regulation, cognitive flexibility, and psychopathology during the COVID-19 pandemic: a multi-wave study. Scientific Reports 2023, 13: 9854. PMID: 37330557, PMCID: PMC10276821, DOI: 10.1038/s41598-023-36211-3.Peer-Reviewed Original ResearchConceptsIntolerance of uncertaintyEmotion regulation difficultiesCognitive controlMulti-wave studyRegulation difficultiesCognitive flexibilityEmotion regulationMental healthMaladaptive emotion regulationProtective factorsUncertainty intoleranceIndividual differencesMediation analysisMental health burdenCOVID-19 pandemicStress resilienceRisk factorsPsychopathologySignificant mental health burdenOnline assessmentLongitudinal changesNegative effectsDifficultiesHealth burdenAnxietyInternal capsule microstructure mediates the relationship between childhood maltreatment and PTSD following adulthood trauma exposure
Wong S, Lebois L, Ely T, van Rooij S, Bruce S, Murty V, Jovanovic T, House S, Beaudoin F, An X, Zeng D, Neylan T, Clifford G, Linnstaedt S, Germine L, Bollen K, Rauch S, Haran J, Storrow A, Lewandowski C, Musey P, Hendry P, Sheikh S, Jones C, Punches B, Kurz M, Swor R, Hudak L, Pascual J, Seamon M, Pearson C, Peak D, Merchant R, Domeier R, Rathlev N, O’Neil B, Sergot P, Sanchez L, Miller M, Pietrzak R, Joormann J, Barch D, Pizzagalli D, Harte S, Elliott J, Kessler R, Koenen K, McLean S, Ressler K, Stevens J, Harnett N. Internal capsule microstructure mediates the relationship between childhood maltreatment and PTSD following adulthood trauma exposure. Molecular Psychiatry 2023, 28: 5140-5149. PMID: 36932158, PMCID: PMC10505244, DOI: 10.1038/s41380-023-02012-3.Peer-Reviewed Original ResearchInternal capsuleDiffusion tensor imagingPosttraumatic dysfunctionWhite matter microstructureFractional anisotropyPTSD symptomsChildhood traumaRecent traumaChildhood maltreatmentTrauma exposureBilateral internal capsuleFuture PTSD symptomsAdulthood trauma exposureChildhood trauma exposureStress-related disordersWhite matter tractsPCL-5 scoresAssessment of PTSDSensory fibersEmergency departmentRisk factorsCorpus callosumNeural pathwaysCingulum bundleNeural circuitsUse of serial smartphone-based assessments to characterize diverse neuropsychiatric symptom trajectories in a large trauma survivor cohort
Beaudoin F, An X, Basu A, Ji Y, Liu M, Kessler R, Doughtery R, Zeng D, Bollen K, House S, Stevens J, Neylan T, Clifford G, Jovanovic T, Linnstaedt S, Germine L, Rauch S, Haran J, Storrow A, Lewandowski C, Musey P, Hendry P, Sheikh S, Jones C, Punches B, Kurz M, Swor R, Murty V, McGrath M, Hudak L, Pascual J, Datner E, Chang A, Pearson C, Peak D, Merchant R, Domeier R, Rathlev N, Neil B, Sergot P, Sanchez L, Bruce S, Baker J, Joormann J, Miller M, Pietrzak R, Barch D, Pizzagalli D, Sheridan J, Smoller J, Harte S, Elliott J, Koenen K, Ressler K, McLean S. Use of serial smartphone-based assessments to characterize diverse neuropsychiatric symptom trajectories in a large trauma survivor cohort. Translational Psychiatry 2023, 13: 4. PMID: 36609484, PMCID: PMC9823011, DOI: 10.1038/s41398-022-02289-y.Peer-Reviewed Original Research