Social Anxiety Reduces Visual Attention to the Eyes of Emotional Faces in Autistic Youth
Franke C, Griffin J, Naples A, Wolf J, McPartland J. Social Anxiety Reduces Visual Attention to the Eyes of Emotional Faces in Autistic Youth. Journal Of Autism And Developmental Disorders 2024, 1-13. PMID: 39556296, DOI: 10.1007/s10803-024-06636-4.Peer-Reviewed Original ResearchNon-autistic participantsSocial attentionSocial anxietyEye contactAutistic youthEyes of emotional facesSA characteristicsEye trackingReduced eye contactSelf-reported SAReduced visual attentionNon-autistic childrenEmotional facesAutistic participantsPsychiatric characteristicsNon-autistic youthAutistic individualsEmotional expressionVisual attentionEye regionBehavioral featuresSocial interactionAutismParticipantsCo-occurrence11C-UCB-J PET imaging is consistent with lower synaptic density in autistic adults
Matuskey D, Yang Y, Naganawa M, Koohsari S, Toyonaga T, Gravel P, Pittman B, Torres K, Pisani L, Finn C, Cramer-Benjamin S, Herman N, Rosenthal L, Franke C, Walicki B, Esterlis I, Skosnik P, Radhakrishnan R, Wolf J, Nabulsi N, Ropchan J, Huang Y, Carson R, Naples A, McPartland J. 11C-UCB-J PET imaging is consistent with lower synaptic density in autistic adults. Molecular Psychiatry 2024, 1-7. PMID: 39367053, DOI: 10.1038/s41380-024-02776-2.Peer-Reviewed Original ResearchPositron emission tomographySynaptic densityAutistic adultsBrain regionsAutistic featuresClinical phenotype of autismNon-autistic participantsPhenotype of autismNon-autistic individualsRelationship to clinical characteristicsSynaptic vesicle glycoprotein 2AAssociated with clinical measuresPost-mortem studiesPositron emission tomography scanPrefrontal cortexClinician ratingsAutism groupNeural basisBrain areasNeural processesBetween-group differencesVolumetric differencesBinding potentialDensity of synapsesAutism