2023
Investigating the Face Inversion Effect in Autism Across Behavioral and Neural Measures of Face Processing
Griffin J, Azu M, Cramer-Benjamin S, Franke C, Herman N, Iqbal R, Keifer C, Rosenthal L, McPartland J. Investigating the Face Inversion Effect in Autism Across Behavioral and Neural Measures of Face Processing. JAMA Psychiatry 2023, 80: 1026-1036. PMID: 37405787, PMCID: PMC10323765, DOI: 10.1001/jamapsychiatry.2023.2105.Peer-Reviewed Original ResearchFace processing systemFace inversion effectAutism spectrum disorderInversion effectFace processingNeurotypical sampleAutistic individualsEffect sizeHuman social cognitionPerformance differencesFace recognition taskPerformance-based measuresSocial cognitionNeural measuresNeurotypical individualsPsychological constructsNeural responsesSpectrum disorderElectrophysiological measuresRecognition taskBrain functioningBehavioral paradigmsRecognition demandsIdentity recognitionNeural systems
2022
Neural correlates of eye contact and social function in autism spectrum disorder
Hirsch J, Zhang X, Noah J, Dravida S, Naples A, Tiede M, Wolf J, McPartland J. Neural correlates of eye contact and social function in autism spectrum disorder. PLOS ONE 2022, 17: e0265798. PMID: 36350848, PMCID: PMC9645655, DOI: 10.1371/journal.pone.0265798.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderDorsal parietal regionsNeural correlatesEye contactLive eyesNeural responsesSpectrum disorderAutism Diagnostic Observation ScheduleUnderlying neural correlatesSocial Responsiveness ScaleGold standard measureCentral diagnostic criterionDiagnostic criteriaDiagnostic biomarkersSRS-2ADOS-2Responsiveness ScaleObservation ScheduleParietal regionsPupillometry dataNeural systemsEyesNatural interactionDisordersCorrelates
2018
Neurophysiological correlates of holistic face processing in adolescents with and without autism spectrum disorder
Naumann S, Senftleben U, Santhosh M, McPartland J, Webb SJ. Neurophysiological correlates of holistic face processing in adolescents with and without autism spectrum disorder. Journal Of Neurodevelopmental Disorders 2018, 10: 27. PMID: 30165814, PMCID: PMC6118009, DOI: 10.1186/s11689-018-9244-y.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderMooney stimuliHolistic processingHolistic faceSpectrum disorderIQ-matched neurotypical controlsFace processing strategiesGamma-band activitySlow response timeMooney imagesFace processingASD engageASD groupERP componentsElectroencephalography (EEG) correlatesNeurophysiological correlatesNeurotypical controlsTemporal processingEarly processingP1 amplitudeNeural systemsProcessing strategiesGamma activityStimuliP1 latency
2014
The Social Neuroscience of Autism Spectrum Disorder
McPartland J, Tillman R, Yang D, Bernier R, Pelphrey K. The Social Neuroscience of Autism Spectrum Disorder. 2014 DOI: 10.1002/9781118911389.hautc20.Peer-Reviewed Original ResearchSocial neuroscienceInformation processingMental state reasoningSocial information processingAtypical brain functionAutism spectrum disorderComplex information processingAction understandingBrain systemsSocial perceptionCommunicative impairmentsSpectrum disorderNeural systemsAlternative accountNeural connectivityASDBrain functionNeuroscienceProcessingConceptual backgroundPathogenesis of autismAutismMore effective strategiesTranslational objectivesPerceptionBuilding a Social Neuroscience of Autism Spectrum Disorder
Pelphrey KA, Yang D, McPartland JC. Building a Social Neuroscience of Autism Spectrum Disorder. 2014, 16: 215-233. PMID: 24481546, DOI: 10.1007/7854_2013_253.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderSpectrum disorderReciprocal social interactionComplex information processingSocial neuroscienceSocial informationSocial dysfunctionEarly-onset neurodevelopmental disorderNeural systemsInformation processingSocial interactionNeurodevelopmental disordersAlternative interpretationDisordersConceptual backgroundProcessingNeuroscienceEtiologic diversityImpairmentGreat phenotypic heterogeneityConsequent difficultyDifficulties
2012
Neural Mechanisms of Improvements in Social Motivation After Pivotal Response Treatment: Two Case Studies
Voos AC, Pelphrey KA, Tirrell J, Bolling DZ, Wyk B, Kaiser MD, McPartland JC, Volkmar FR, Ventola P. Neural Mechanisms of Improvements in Social Motivation After Pivotal Response Treatment: Two Case Studies. Journal Of Autism And Developmental Disorders 2012, 43: 1-10. PMID: 23104615, PMCID: PMC4999079, DOI: 10.1007/s10803-012-1683-9.Peer-Reviewed Original ResearchConceptsPivotal Response TreatmentAutism spectrum disorderSocial stimuliResponse treatmentFunctional magnetic resonance imagingYoung childrenNeural correlatesSocial motivationSocial skillsSocial perceptionNeural mechanismsNeural responsesBehavioral measuresSpectrum disorderSocial communicationBehavioral treatmentEye trackingNeural systemsAdaptive behaviorBrain regionsBaseline measuresStriking gainsStimuliChildrenPositive effect
2010
Dissociable brain mechanisms for processing social exclusion and rule violation
Bolling DZ, Pitskel NB, Deen B, Crowley MJ, McPartland JC, Mayes LC, Pelphrey KA. Dissociable brain mechanisms for processing social exclusion and rule violation. NeuroImage 2010, 54: 2462-2471. PMID: 20974272, PMCID: PMC3006641, DOI: 10.1016/j.neuroimage.2010.10.049.Peer-Reviewed Original ResearchMeSH KeywordsBrainCerebral CortexComputer GraphicsData Interpretation, StatisticalFemaleGames, ExperimentalHumansImage Processing, Computer-AssistedInterpersonal RelationsMagnetic Resonance ImagingMaleNerve NetNeural PathwaysPsychophysicsRejection, PsychologySocial EnvironmentSocial PerceptionYoung AdultConceptsVentral anterior cingulate cortexBrain regionsMagnetic resonance imaging studyDifferential functional connectivityResonance imaging studyFunctional magnetic resonance imaging studyAnterior cingulate cortexCingulate cortex activityMiddle temporal gyrusLateral parietal cortexVentrolateral prefrontal cortexCingulate cortexParietal cortexImaging studiesCortex activityFunctional connectivityTemporal gyrusPrefrontal cortexPosterior cingulate cortex activityActivation patternsCortexBrain mechanismsFunctional dissociationVirtual ball-tossing gameNeural systems