2018
Adaptive treatment strategies for children and adolescents with Obsessive-Compulsive Disorder: A sequential multiple assignment randomized trial
Fatori D, de Bragança Pereira CA, Asbahr FR, Requena G, Alvarenga PG, de Mathis MA, Rohde LA, Leckman JF, March JS, Polanczyk GV, Miguel EC, Shavitt RG. Adaptive treatment strategies for children and adolescents with Obsessive-Compulsive Disorder: A sequential multiple assignment randomized trial. Journal Of Anxiety Disorders 2018, 58: 42-50. PMID: 30025255, DOI: 10.1016/j.janxdis.2018.07.002.Peer-Reviewed Original ResearchConceptsGroup cognitive behavioral therapySequential multiple assignmentTreatment failureInitial treatmentBaseline Yale-Brown ObsessiveChildhood OCDEffective initial treatmentProvision of treatmentCompulsive Scale scoresCognitive behavioral therapyAdaptive treatment strategiesYale-Brown ObsessiveSame regimenObsessive-compulsive disorderTreatment strategiesSymptom reductionPrimary analysisScale scoreFluoxetineTime pointsWeeksTreatmentChildrenEffect sizeTrials
1995
Risperidone addition in fluvoxamine-refractory obsessive-compulsive disorder: three cases.
McDougle CJ, Fleischmann RL, Epperson CN, Wasylink S, Leckman JF, Price LH. Risperidone addition in fluvoxamine-refractory obsessive-compulsive disorder: three cases. The Journal Of Clinical Psychiatry 1995, 56: 526-8. PMID: 7592506.Peer-Reviewed Original ResearchConceptsSerotonin uptake inhibitorObsessive-compulsive disorderYale-Brown Obsessive Compulsive ScaleY-BOCS scoresRisperidone additionOCD patientsComorbid chronic tic disorderPatients' Y-BOCS scoresRefractory obsessive-compulsive disorderOpen-label mannerLow-dose haloperidolSide effect profileWeeks of treatmentChronic tic disorderEffective treatment strategiesObsessive Compulsive ScaleSUI treatmentEffect profileNeuroleptic treatmentTardive dyskinesiaTypical neurolepticsModerate sedationReceptor antagonistTic disordersTreatment strategies
1993
Limited therapeutic effect of addition of buspirone in fluvoxamine- refractory obsessive-compulsive disorder
McDougle CJ, Goodman WK, Leckman JF, Holzer JC, Barr LC, McCance-Katz E, Heninger GR, Price LH. Limited therapeutic effect of addition of buspirone in fluvoxamine- refractory obsessive-compulsive disorder. American Journal Of Psychiatry 1993, 150: 647-649. PMID: 8465885, DOI: 10.1176/ajp.150.4.647.Peer-Reviewed Original Research