2023
Predictors of Functional Impairment in Bipolar Disorder: Results From 13 Cohorts From Seven Countries by the Global Bipolar Cohort Collaborative
Burdick K, Millett C, Yocum A, Altimus C, Andreassen O, Aubin V, Belzeaux R, Berk M, Biernacka J, Blumberg H, Cleare A, Diaz-Byrd C, Dubertret C, Etain B, Eyler L, Forester B, Fullerton J, Frye M, Gard S, Godin O, Haffen E, Klaus F, Lagerberg T, Leboyer M, Martinez-Aran A, McElroy S, Mitchell P, Olie E, Olorunfemi P, Passerieux C, Peters A, Pham D, Polosan M, Potter J, Sajatovic M, Samalin L, Schwan R, Shanahan M, Solé B, Strawbridge R, Stuart A, Torres I, Ueland T, Vieta E, Williams L, Wrobel A, Yatham L, Young A, Nierenberg A, McInnis M. Predictors of Functional Impairment in Bipolar Disorder: Results From 13 Cohorts From Seven Countries by the Global Bipolar Cohort Collaborative. FOCUS The Journal Of Lifelong Learning In Psychiatry 2023, 21: 444-452. PMID: 38694997, PMCID: PMC11058953, DOI: 10.1176/appi.focus.23021021.Peer-Reviewed Original ResearchBipolar disorderFunctional impairmentComplete recoveryComorbid substance use disorderPersistent functional impairmentPatient's complete recoveryLogistic regression analysisPrior mood episodesProspective longitudinal studySubstance use disordersPsychotropic medicationsHeterogeneous presentationMood episodesClinical research communityDepressive symptomsOptimizing outcomesUse disordersCohortLower functioningLongitudinal studyRegression analysisGreater total numberHigh rateMultiple cohortsImpairment
2022
Bipolar I and bipolar II subtypes in older age: Results from the Global Aging and Geriatric Experiments in Bipolar Disorder (GAGE‐BD) project
Beunders A, Klaus F, Kok A, Schouws S, Kupka R, Blumberg H, Briggs F, Eyler L, Forester B, Forlenza O, Gildengers A, Jimenez E, Mulsant B, Patrick R, Rej S, Sajatovic M, Sarna K, Sutherland A, Yala J, Vieta E, Villa L, Korten N, Dols A. Bipolar I and bipolar II subtypes in older age: Results from the Global Aging and Geriatric Experiments in Bipolar Disorder (GAGE‐BD) project. Bipolar Disorders 2022, 25: 43-55. PMID: 36377516, PMCID: PMC10265276, DOI: 10.1111/bdi.13271.Peer-Reviewed Original ResearchConceptsBD II patientsStudy cohortBD subtypesSomatic burdenMultivariable analysisGeneral functioningBD-IIGlobal AGEingBD-I patientsCross-sectional analysisClinical factorsClinical differencesSevere depressionPsychiatric hospitalizationBipolar ICognitive impairmentLate onsetPatientsOlder ageDiagnostic definitionSubtypesGeneralized linear mixed modelCohortLinear mixed modelsRandom interceptPredictors of functional impairment in bipolar disorder: Results from 13 cohorts from seven countries by the global bipolar cohort collaborative
Burdick KE, Millett CE, Yocum AK, Altimus CM, Andreassen OA, Aubin V, Belzeaux R, Berk M, Biernacka JM, Blumberg H, Cleare AJ, Diaz‐Byrd C, Dubertret C, Etain B, Eyler LT, Forester BP, Fullerton JM, Frye MA, Gard S, Godin O, Haffen E, Klaus F, Lagerberg TV, Leboyer M, Martinez‐Aran A, McElroy S, Mitchell PB, Olie E, Olorunfemi P, Passerieux C, Peters AT, Pham DL, Polosan M, Potter JR, Sajatovic M, Samalin L, Schwan R, Shanahan M, Solé B, Strawbridge R, Stuart AL, Torres I, Ueland T, Vieta E, Williams LJ, Wrobel AL, Yatham LN, Young AH, Nierenberg AA, McInnis MG. Predictors of functional impairment in bipolar disorder: Results from 13 cohorts from seven countries by the global bipolar cohort collaborative. Bipolar Disorders 2022, 24: 709-719. PMID: 35322518, PMCID: PMC9500115, DOI: 10.1111/bdi.13208.Peer-Reviewed Original ResearchConceptsBipolar disorderFunctional impairmentComplete recoveryComorbid substance use disorderPersistent functional impairmentPatient's complete recoveryPrior mood episodesLogistic regression analysisProspective longitudinal studySubstance use disordersPsychotropic medicationsHeterogeneous presentationBipolar cohortMood episodesClinical research communityDepressive symptomsOptimizing outcomesUse disordersCohortLower functioningImpairmentLongitudinal studyDisordersRegression analysisGreater total number