Toward a Digital Future in Bipolar Disorder Assessment: A Systematic Review of Disruptions in the Rest-Activity Cycle as Measured by Actigraphy
Panchal P, de Queiroz Campos G, Goldman DA, Auerbach RP, Merikangas KR, Swartz HA, Sankar A, Blumberg HP. Toward a Digital Future in Bipolar Disorder Assessment: A Systematic Review of Disruptions in the Rest-Activity Cycle as Measured by Actigraphy. Frontiers In Psychiatry 2022, 13: 780726. PMID: 35677875, PMCID: PMC9167949, DOI: 10.3389/fpsyt.2022.780726.Peer-Reviewed Original ResearchRest-activity patternsBipolar disorderSystematic reviewDepressive episodeActigraphy measuresMore adverse outcomesLonger sleep onset latencyComprehensive systematic reviewDaily activitiesCurrent systematic reviewSleep onset latencyUse of actigraphyRest-activity cycleActivity patternsSpecific phenotypic markersTherapeutic optionsAdverse outcomesEmbase databasesManic symptomsPRISMA guidelinesPrevention optionsOnset latencyPredictive valueCognitive impairmentOverall daily activityNeuroimaging Studies of Brain Structure in Older Adults with Bipolar Disorder: A Review
Rajashekar N, Blumberg HP, Villa LM. Neuroimaging Studies of Brain Structure in Older Adults with Bipolar Disorder: A Review. Journal Of Psychiatry And Brain Science 2022, 7: e220006. PMID: 36092855, PMCID: PMC9453888, DOI: 10.20900/jpbs.20220006.Peer-Reviewed Original ResearchBipolar disorderWhite matterBrain regionsBrain differencesDiffusion-weighted magnetic resonance imaging studiesOlder adultsMagnetic resonance imaging studyMood-stabilizing medicationsWhite matter findingsGray matter reductionsLater lifeCommon mood disorderYounger age groupsResonance imaging studyStructural brain differencesSubcortical brain regionsAdverse outcomesCognitive dysfunctionBrain changesClinical dataMood disordersProtective effectElevated riskHigh riskCognitive symptoms