2006
Effects of Short- and Long-Term Risperidone Treatment on Prolactin Levels in Children with Autism
Anderson GM, Scahill L, McCracken JT, McDougle CJ, Aman MG, Tierney E, Arnold LE, Martin A, Katsovich L, Posey DJ, Shah B, Vitiello B. Effects of Short- and Long-Term Risperidone Treatment on Prolactin Levels in Children with Autism. Biological Psychiatry 2006, 61: 545-550. PMID: 16730335, DOI: 10.1016/j.biopsych.2006.02.032.Peer-Reviewed Original ResearchConceptsRisperidone-induced increasesLong-term risperidone treatmentProlactin levelsRisperidone treatmentSerum prolactinOpen-label followWeeks of risperidoneBaseline prolactin levelsEffects of ShortPlacebo groupProlactin elevationReceptor polymorphismsWeek 8Baseline levelsMean increaseProlactinRisperidoneSerum samplesAdverse effectsPlaceboChildrenTreatmentMonthsDRD2 allelesAdolescents
2000
Cerebrospinal Fluid Corticotropin-Releasing Hormone in Healthy Humans: Effects of Yohimbine and Naloxone1
Vythilingam M, Anderson G, Owens M, Halaszynski T, Bremner J, Carpenter L, Heninger G, Nemeroff C, Charney D. Cerebrospinal Fluid Corticotropin-Releasing Hormone in Healthy Humans: Effects of Yohimbine and Naloxone1. The Journal Of Clinical Endocrinology & Metabolism 2000, 85: 4138-4145. PMID: 11095445, DOI: 10.1210/jcem.85.11.6968.Peer-Reviewed Original ResearchConceptsCRH neuronsParaventricular nucleusCSF CRHCerebrospinal fluidPlasma cortisolHypothalamic pituitary adrenal axis activityCSF CRH concentrationsCSF CRH levelsCorticotropin-Releasing HormoneCSF NE levelsEffects of yohimbineAdult normal volunteersPlasma cortisol concentrationsCRH concentrationsCentral norepinephrineOpioid regulationPlacebo administrationPVN neuronsCRH levelsNE levelsCSF norepinephrineHPA axisAxis activityHealthy humansMedian eminence
1991
Reproducibility and temporal stability of ADP‐induced platelet aggregation: Comparison of the anticoagulants sodium citrate and D‐phenylalanyl‐L‐prolyl‐L‐arginyl chloromethyl ketone
Horne W, Cohen D, Anderson G. Reproducibility and temporal stability of ADP‐induced platelet aggregation: Comparison of the anticoagulants sodium citrate and D‐phenylalanyl‐L‐prolyl‐L‐arginyl chloromethyl ketone. American Journal Of Hematology 1991, 38: 48-53. PMID: 1897514, DOI: 10.1002/ajh.2830380108.Peer-Reviewed Original Research
1989
Whole blood serotonin and tryptophan in autism: Temporal stability and the effects of medication
Minderaa R, Anderson G, Volkmar F, Harcherick D, Akkerhuis G, Cohen D. Whole blood serotonin and tryptophan in autism: Temporal stability and the effects of medication. Journal Of Autism And Developmental Disorders 1989, 19: 129-136. PMID: 2708296, DOI: 10.1007/bf02212724.Peer-Reviewed Original ResearchConceptsWhole blood serotoninPlatelet countMedicated groupBlood serotoninSex-matched normal controlsSignificant intraclass correlation coefficientsEffects of medicationWhole blood concentrationsAutistic groupIntraclass correlation coefficientMean percentage differenceBlood concentrationsNormal controlsNormal subjectsWhole bloodTRP valuesSerotoninTryptophan valuesYear periodGroupCountPercentage differenceMedicationsBlood
1987
Plasma-free homovanillic acid: Within- and across-day stability in children and adults with tourette's syndrome
Riddle M, Leckman J, Anderson G, Ort S, Hardin M, Stevenson J, Cohen D. Plasma-free homovanillic acid: Within- and across-day stability in children and adults with tourette's syndrome. Life Sciences 1987, 40: 2145-2151. PMID: 3473273, DOI: 10.1016/0024-3205(87)90004-x.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultChildCircadian RhythmFemaleHomovanillic AcidHumansMaleMiddle AgedTime FactorsTourette Syndrome
1985
Effect of a Meal on Human Whole Blood Serotonin
Anderson G, Feibel F, Wetlaufer L, Schlicht K, Ort S, Cohen D. Effect of a Meal on Human Whole Blood Serotonin. Gastroenterology 1985, 88: 86-89. PMID: 2578039, DOI: 10.1016/s0016-5085(85)80137-2.Peer-Reviewed Original ResearchConceptsWhole blood serotoninMicrograms/hBlood serotoninGastrointestinal hormonesUrinary excretionSerotonin levelsBlood samplesUrine specimensBaseline levelsSerotoninSecond hourWhole bloodHuman subjectsSpecific high-performance liquid chromatographic methodMealMinSubjectsUrinaryLevelsExcretionBloodHormone
1982
Psychopharmacology of attention deficit disorder: pharmacokinetic, neuroendocrine, and behavioral measures following acute and chronic treatment with methylphenidate.
Shaywitz S, Hunt R, Jatlow P, Cohen D, Young J, Pierce R, Anderson G, Shaywitz B. Psychopharmacology of attention deficit disorder: pharmacokinetic, neuroendocrine, and behavioral measures following acute and chronic treatment with methylphenidate. Pediatrics 1982, 69: 688-94. PMID: 7079034, DOI: 10.1542/peds.69.6.688.Peer-Reviewed Original ResearchConceptsAcute studyMPH concentrationsGrowth hormoneObserved maximal concentrationCentral dopaminergic mechanismsPeak plasma concentrationAdministration of medicationsPharmacokinetics of methylphenidatePlasma growth hormoneConcentrations of methylphenidatePlasma MPH concentrationsAttention deficit disorderClinical responseChronic treatmentDopaminergic mechanismsGroup of childrenDisorders of attentionAbbreviated Conners' Rating ScaleSchool-aged childrenOral administrationPlasma concentrationsClinical pharmacologyMPH administrationProlactin concentrationsPercentage of improvement
1979
Rapid liquid chromatographic determination of tryptophan, tyrosine, 5-hydroxyindoleacetic acid and homovanillic acid in cerebrospinal fluid
Anderson G, Young J, Cohen D. Rapid liquid chromatographic determination of tryptophan, tyrosine, 5-hydroxyindoleacetic acid and homovanillic acid in cerebrospinal fluid. Journal Of Chromatography 1979, 164: 501-505. PMID: 541426, DOI: 10.1016/s0378-4347(00)81553-4.Peer-Reviewed Original Research