1987
Parotid Gland Salivary Secretion in Tourette's Syndrome and Attention Deficit Disorder: A Model System for the Study of Neurochemical Regulation
COHEN D, ORT S, CARUSO K, ANDERSON G, HUNT R, SHAYWITZ B, KREMENITZER M, LECKMAN J. Parotid Gland Salivary Secretion in Tourette's Syndrome and Attention Deficit Disorder: A Model System for the Study of Neurochemical Regulation. Journal Of The American Academy Of Child & Adolescent Psychiatry 1987, 26: 65-68. PMID: 3034852, DOI: 10.1097/00004583-198701000-00013.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAttention Deficit Disorder with HyperactivityChildClonidineFemaleHumansMaleParotid GlandReceptors, AdrenergicTourette SyndromeConceptsAttention deficit disorderTourette syndromeSalivary amylase concentrationTS patientsAmylase concentrationSalivary secretionNeurochemical regulationReceptor functioningTreatment of TSDeficit disorderSalivary amylase secretionParotid gland secretionSingle dosesSalivary volumeClonidinePatientsAmylase secretionSyndromeADD patientsSalivary measuresSecretionTotal amylaseSalivary amylaseDisordersChildren
1984
Whole blood serotonin and tryptophan levels in Tourette's disorder: Effects of acute and chronic clonidine treatment
Leckman J, Anderson G, Cohen D, Ort S, Harcherik D, Hoder E, Shaywitz B. Whole blood serotonin and tryptophan levels in Tourette's disorder: Effects of acute and chronic clonidine treatment. Life Sciences 1984, 35: 2497-2503. PMID: 6595491, DOI: 10.1016/0024-3205(84)90435-1.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultChildClonidineHumansMiddle AgedReceptors, AdrenergicSerotoninTourette SyndromeTryptophanConceptsChronic clonidine treatmentClonidine treatmentTourette's disorder patientsWhole blood serotoninDisorder patientsTourette's disorderBlood serotoninTryptophan levelsMean differenceChronic treatmentAcute doseNormal controlsMean increaseClonidinePatientsDisordersMode of actionTreatmentSignificant differencesSerotoninBaseline conditionsLevelsDifferencesDoseParotid Salivary Response to Clonidine in Tourette's Syndrome: Indicator of Adrenergic Responsivity
SELINGER D, COHEN D, ORT S, ANDERSON G, CARUSO K, LECKMAN J. Parotid Salivary Response to Clonidine in Tourette's Syndrome: Indicator of Adrenergic Responsivity. Journal Of The American Academy Of Child & Adolescent Psychiatry 1984, 23: 392-398. PMID: 6205037, DOI: 10.1016/s0002-7138(09)60316-2.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAmylasesChildClonidineHumansParotid GlandReceptors, AdrenergicSalivationTourette SyndromeConceptsDrug-free patientsSalivary volumeTS patientsTourette syndromeSingle doseAdrenergic receptorsLong-term clonidine treatmentAmylase secretionGood therapeutic responseYoung male patientParotid salivary responseAdrenergic responsivityClonidine treatmentSalivary amylase concentrationMale patientsTherapeutic responseNoradrenergic functioningAmylase concentrationPatientsClonidineParotid glandSyndromeSalivary responseT patientsTotal secretion