1993
Platelet serotonin studies in hyperserotonemic relatives of children with autistic disorder
Cook E, Arora R, Anderson G, Berry-Kravis E, Yan S, Yeoh HC, Sklena P, Charak D, Leventhal B. Platelet serotonin studies in hyperserotonemic relatives of children with autistic disorder. Life Sciences 1993, 52: 2005-2015. PMID: 7684805, DOI: 10.1016/0024-3205(93)90685-v.Peer-Reviewed Original ResearchConceptsLysergic acid diethylamideParoxetine bindingWhole bloodSubgroup of subjectsHyperserotonemia of autismProstaglandin E1Arginine vasopressinDensity of plateletsCAMP productionAcid diethylamideLSD bindingAutistic disorderSignificant differencesSignificant correlationBloodSubjectsBasalSubgroupsPlateletsChildrenAutistic probandsUptake VmaxAutistic children
1989
Whole blood serotonin and tryptophan in autism: Temporal stability and the effects of medication
Minderaa R, Anderson G, Volkmar F, Harcherick D, Akkerhuis G, Cohen D. Whole blood serotonin and tryptophan in autism: Temporal stability and the effects of medication. Journal Of Autism And Developmental Disorders 1989, 19: 129-136. PMID: 2708296, DOI: 10.1007/bf02212724.Peer-Reviewed Original ResearchConceptsWhole blood serotoninPlatelet countMedicated groupBlood serotoninSex-matched normal controlsSignificant intraclass correlation coefficientsEffects of medicationWhole blood concentrationsAutistic groupIntraclass correlation coefficientMean percentage differenceBlood concentrationsNormal controlsNormal subjectsWhole bloodTRP valuesSerotoninTryptophan valuesYear periodGroupCountPercentage differenceMedicationsBlood
1987
WHOLE BLOOD SEROTONIN IN AUTISTIC AND NORMAL SUBJECTS
Anderson G, Freedman D, Cohen D, Volkmar F, Hoder E, McPhedran P, Minderaa R, Hansen C, Young J. WHOLE BLOOD SEROTONIN IN AUTISTIC AND NORMAL SUBJECTS. Journal Of Child Psychology And Psychiatry 1987, 28: 885-900. PMID: 3436995, DOI: 10.1111/j.1469-7610.1987.tb00677.x.Peer-Reviewed Original ResearchConceptsWhole blood serotoninSerotonin levelsBlood serotoninNormal subjectsWhole blood serotonin concentrationAutistic subjectsBlood serotonin concentrationsBlood tryptophan levelsLow serotonin levelsHyperserotonemia of autismPlatelet countSerotonin concentrationsNormal groupTryptophan levelsSerotoninAutistic groupSubjectsPossible causesAnticonvulsantsNeurolepticsGroupLevelsHyperserotonemia